1855 United States Tycoon
Chapter 58 Drug Experiments
In the laboratory, Scotch Herb used dozens of rabbits to verify the efficacy of the sulfonamide he made, and found that it was indeed very effective in killing bacteria, and the rabbits were still alive after the medication. There is nothing but Death, only two are alive and kicking, and they always like to rub their bodies on the wall of the cage.
"Boss, do you think there is something wrong with these two rabbits?" The experimenter Hanks was more concerned about the safety of the drug than Scrooge, so he quickly reminded that he was about to fill in the side effects column on the research report. "No obvious side effects" Shi Gaozhi.
"Oh, don't you think they are alive and kicking?" Scrooge said dismissively.
Scrooge certainly knows what that is all about, that is the typical reaction of sulfa allergy. Like other antibiotics, sulfa can cause allergic reactions. Moreover, sulfa allergies are more difficult to detect in advance than things like penicillin. Fortunately, the severity of allergic reactions to sulfa drugs is much gentler than penicillin and the like. It is nothing more than skin reactions and pulmonary reactions. Well, there are some drug rashes, and then a little bit of asthma. Although it can also cause shock in severe cases, the probability of this is very low. Generally speaking, sulfa allergy can't kill people.
But Hanks is unwilling to let the problem go. Hanks is a new immigrant. According to his own statement, he studied in the Department of Chemistry at the University of Hamburg. However, he did not have a diploma, because he violated the laboratory's operating procedures and was discovered to conduct experiments privately, and was expelled.
Scrooge didn't know whether Hanks was saying true or not, but he asked Hanks a few questions and asked him to perform some experiments, and found that Hanks was indeed trained in this area. , So I kept this guy. Of course Scrooge would not give him a college student's salary.
Hanks took the two rabbits out of the cage and observed them carefully.
"Boss, there are some herpes on the skins of these two rabbits, especially on the lips, anus and other parts."
This is the typical symptom of sulfa drug allergy. Scrooge nodded and said, "Stop the medication for these two rabbits, give them plenty of water, and then check the situation. Well, Hanks, this is up to you."
A week later, Hanks ran to report: "Boss, the two rabbits are all right."
"Oh, I see. Where are the other rabbits?" Scrooge asked without looking up.
"It's all very good," Hanks replied.
"Well, then drag those rabbits back to the market and sell them to recover the cost. In addition, we are ready to go to the hospital tomorrow for clinical trials."
"So fast! The biological experiment has just been completed..." In fact, Hanks felt that the sloppy biological experiment was not completely completed.
"Because a few patients with sepsis are about to die, they will have to see God if they don't go," Scrooge said. Question, for them, where else can they go?"
Hospitals in the nineteenth century were still a loathsome place, not only because in the era when antibiotics had not yet been discovered, doctors actually did not have any particularly effective solutions for many diseases. It was also because at that time, people didn't even know the relationship between bacteria and disease. Of course, there was no way to talk about disinfection and sterilization. A scalpel, after dissecting the corpse of a patient who died of tetanus, may only be wiped with a towel, and then used to perform an operation on another temporarily alive patient. The bed sheets under the cholera patient may not even be cleaned, so they were spread on the bed of another patient. As a result, when patients arrive at the hospital, not only will they not receive effective treatment, they will also infect each other. As a result, they enter the hospital vertically and carry them out horizontally. Take obstetrics and gynecology as an example. In most of the nineteenth century, the death rate of pregnant women who went to the hospital to give birth was more than ten to one hundred times higher than the death rate of their own birth at home. Death caused by bacterial infection after production even competes with cholera smallpox. The patients and their families actually know this. Therefore, the patients who are sent to the hospital are either dying or because the disease is contagious. In fact, before many people were sent to the hospital, the family had funerals for her in advance. As far as the advantages of hospitals in the nineteenth century are concerned, the only advantage is that there is no medical trouble. Because going to the hospital means death is already a social consensus.
A few days ago, Scrooge's people came to this charity hospital called "Salvation" affiliated to the Baptist Church and explained to the dean that they have a new drug that has a miraculous effect on sepsis, which has been obtained in animal experiments. Very good results, I hope to find a few patients with sepsis in this hospital to test the efficacy of the drug.
If this kind of thing is placed in the 21st century, it is definitely a very troublesome thing. The hospital director would never agree that such an unqualified businessman would come to the hospital to test new drugs. But, fortunately, at this time in the 19th century, there was no strict qualification management system at all. As long as the patient or the patient’s family signed the drug test, there was absolutely no control. Not to mention this is a lovely charity hospital. The so-called charity hospitals are generally "free" hospitals run by churches or other organizations. Patients who come to such hospitals for treatment generally have two characteristics: first, they have no money; second, they are basically helpless. Convincing such patients to sign a voluntary trial of a new drug that may save their lives is simply a simple matter.
As a free charity hospital, the "Salvation" hospital is small in scale. Its entire campus is a disused warehouse. Outpatient clinics, wards, and operating rooms are all in that large warehouse. Because the hospital is rebuilt from a warehouse, the lighting conditions are very poor. So that when Scrooge and a few assistants, under the protection of a few security guards in Heishui (no way, the hospital is in a slum area, where the security has always been very chaotic) came in from the gate of the hospital, their eyes did not adapt for a long time. come over.
After a while, Scrooge could see the situation in the hospital clearly: several hospital beds were laid out in a dark corner, and there were old black blood stains on the yellow sheets. The ground was piled with all kinds of dirty things, and swarms of blow flies were buzzing there. The operating room was simply cut off by a curtain.
"Hello, Mr. Scrooge, I am the head of the hospital Heathfeld." A little old man stretched out his hand to Scrooge. Well, it seems that there is still blood on that hand cleaned or something. s things.
Scrooge glanced at the guy, and did not stretch out his own hand, but put his own hand into the pocket of hundreds of millions.
"What a joke, when I don't know what kind of virtues the hospitals of the 19th century are like? This is definitely a petri dish of all kinds of pathogenic bacteria! Look at your hand again, God knows what's on it? I'm stupid. I shook hands with you!" Scrooge thought.
Seeing Scrooge's actions, the dean was not too embarrassed, because he also realized that his own hands were a bit too dirty. So he wiped his hand on his apron at random, and said to Scrooge: "I'm sorry, I just delivered a girl to the baby, but I haven't had time..."
Because Scrooge had promised to donate a little to this hospital, the dean seemed extraordinarily attentive. He told Scrooge that there are now four patients in this hospital who have symptoms of sepsis due to various reasons. After learning that there is a drug that might save their lives, they all expressed their willingness to receive treatment.
"Well, then let them sign the power of attorney." Scrooge said, he didn't want to stay in this place for a minute. The air in this place is full of germs, which is too dangerous.The dean brought a few people to the bedside, and Scrooge's entourage took out the authorization agreement from the purse. If this agreement is placed in later generations, it will definitely be a typical illegal agreement. Because it deprives the patient of almost any rights, according to it, no matter what problems the patient has afterwards, Scrooge will not bear any responsibility. When the lawyer Scrooge asked for drafted this agreement for Scrooge, Scrooge was worried about whether it was legal. But the lawyer told him that all such agreements are like this. This thing is absolutely legal. So Scrooge heartily sighed: "This is really a golden age for the rich!"
Those patients who are about to be called by the Lord to leave will naturally not have any objections to this agreement. In fact, at this moment, you just stretched out your long claws, took out an agreement written on parchment with mysterious flames, and told them that as long as they sign, they will not die, um, no Fewer patients will also sign.
Seeing that the patient had signed, Scrooge motioned Hanks to take out the medicine to the dean, and told him the dosage and precautions of the medicine. Scrooge noticed the light flashing in the eyes of the patients when they saw the glass bottle with the medicine, which made him very uncomfortable. "When did I have boring sympathy for these NPCs?" Scrooge thought.
Walking out of the hospital, Scrooge got into the carriage without saying a word, and Hanks sat next to him.
"Hanks, just came out of the hospital, what do you think?" Scrooge said.
"It's terrible! People who are not sick will die there too. If one day I get sick, I would rather shoot myself in the head than sleep in such a dirty place."
"The rich people’s hospital is not like this, Hanks. In this world, heaven and The Underworld are real. If you have money, you will live in heaven. If you have no money, you will fall into The Underworld. Underworld. Make money!" Scrooge said.
"Boss, you are right. I must work hard to earn more money and live a good life." Hanks thought Scrooge was encouraging him, so he replied. He didn't know that Scrooge's words were more for himself.
Perhaps it is because the germs of this era are still very pure, and they have not been poisoned by various chemical and biological weapons called antibiotics, so there is no time to develop resistance and other things. Therefore, the effects of these drugs are amazing. According to the news from the "Salvation" hospital, after only one week of treatment, the four patients have gradually recovered. It seems that the scope of the test can already be expanded. And the time for the drug to finally be put on the market should not be far away.
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