Back To The Age Of The 80s

"I'm old, I'm really old, but after two or three days, this head doesn't seem to belong to my own." Su Changzhi stretched out and put the last tube of antibiotic extract into the incubator.

In the past few days, the professors of Xiangjiang University School of Medicine, headed by Su Changzhi, completely put down their work and soaked in the laboratory with Li Zheng. When hungry, they ate some bread, and when they were sleepy, they leaned on the table and squinted for a while. With concerted efforts, two hundred carbapenem antibiotics were sent to Queen Mary Hospital.

"Professor Xu just called. He has completely escaped the dangerous period and the wound has recovered well. If there is no accident, he will be discharged from the hospital in a week." Li Zheng smiled and announced the good news to everyone.

The professors were really happy.

"Good Xu Mingsheng, when he is discharged from the hospital, we have to get a good meal from his house, my old arms and legs." An old professor said while pressing his shoulder, causing a burst of laughter in the laboratory. sound.

There was laughter and laughter in Qingyuan, but it was another scene in the hospital.

As of last night, the Queen Mary Hospital confirmed the number of infected 87 people, of whom 78 were successfully passed the dangerous period after being injected with carbapenem antibiotics and have been sent back to the general ward.

But the remaining nine people are either older or suffering from other severe illnesses and extremely weak resistance. Experts from Queen Mary Hospital have assessed that the probability that these people can survive antibiotic nephrotoxicity is less than 20%.

"The patients with 18 beds and 24 beds have signs of organ failure. The condition of the remaining seven people is not very good. The drug-resistant bacteria infection has caused a variety of complications. Whether to inject antibiotics or not, I think we need a collective vote." In the conference room, Chen Xuhua said in a deep voice.

"Without medicine, the death of a patient is a drug-resistant bacteria infection. Normal medical risks are not responsible for the hospital. If the patient dies of drug toxicity after taking the medicine, it is a medical accident. We are doctors, but we are not saints." The middle-aged doctor said.

There was a rustling discussion in the conference room, Chen Sufen pouted and did not speak, Chen Xuhua smiled bitterly.

"Then let's vote." Chen Xuhua patted the table, "Those who are in favor of injection raise their hands."

The meeting room was quiet. Everyone looked at me and I looked at you. No hand was raised.

"Then I will change my question, and raise my hand in favor of no injection!"

There was silence again, and a few minutes later, one hand was raised up alone, and then it seemed as if the movie had pressed the play button, and one hand after another was raised.

In the end, except for Chen Xuhua and Chen Sufen, almost all doctors opposed the injection of carbapenem antibiotics to the remaining nine patients.

Chen Xuhua couldn't express the complexity in his heart. He felt ashamed but at the same time he was relieved.

"In that case, everyone should do a good job of explaining and comforting."

"According to the news from this station, last Wednesday, Queen Mary Hospital announced a large-scale outbreak of Pseudomonas aeruginosa infection in the hospital. A total of 92 people were infected this time. Among them, 78 people have successfully escaped the dangerous period. In the rescue effort. This drug-resistant bacterial infection is coming so fiercely and widely, and it is very rare in the world. According to the hospital's explanation, this is mainly caused by the abuse of antibiotics. At the same time, the reporter learned from relevant medical practitioners. Knowing that in large-scale Pseudomonas aeruginosa infections, the global average survival rate is less than 12%, and Queen Mary Hospital achieved 84.8%, which is a miracle!"

"BBC antibiotic abuse topic, the British textbook will put the Mary Hospital incident in the British medical school textbook!"

"The suspension of the medical school of Hong Kong University is actually related to the fake Mary patina incident!"

"Another Einstein, the original drug inventor once again discovered a new antibiotic!"

After the internal staff of Queen Mary Hospital accidentally leaked their mouths, the reputation of Li Zheng and Li Zheng's laboratory suddenly reached its peak.

"Li Zheng, if this continues, you will have to pay the security guards. I thought that the Xiangjiang paparazzi were all-pervasive. I didn't expect that the reporters of the daily and evening newspapers would also go over the wall." Zheng Lingling said while finishing the experiment table. .

Li Zheng also had a helpless look on his face. He thought he had done much more in his previous life than he did now. At that time, he didn't see reporters blocking the door of his laboratory.

"By the way, didn't you register the patent first this time? Save it like the last time."

Li Zheng shook his head.

"This is still a semi-finished product."

Of course, this is only Li Zheng's excuse. Although carbapenem antibiotics failed the biological test, the drug is still very toxic, but the 84.8% survival rate of the Queen Mary Hospital fully illustrates the practicality of the drug. The molecular structure of the drug is stable enough to apply for a core patent.

Only Li Zheng knew that at this time, Merck, also known as Merck, had already registered the core patents of carbapenem antibiotics, because the patents were still confidential because they involved unlisted new drugs.

It is not difficult for Li Zheng to get a share of the pie. After all, Merck’s imipenem was only listed globally in 1985. With Li Zheng’s foresight, he bypassed the core patents and registered the generics of imipenem first. difficult.

But he did not intend to do so. The pride of being a top scholar in the world does not allow him to do so.

It's just that he thinks so, others don't.

The pursuit of life and health knows no borders. The news that the survival rate of Pseudomonas aeruginosa in Hong Kong Mary Hospital was as high as 84.8% soon spread to the United States across the ocean.

The United States considers itself to be the country with the most advanced medical level, but looking at this miraculous report, it is also the best expert in the United States is dumbfounded.

"The people of Xiangjiang must have developed a new antibiotic! God, the antibiotic of Pseudomonas aeruginosa! This is a milestone in the history of antibiotics."

Merck headquarters in the United States.

Mr. Smith, the president, severely smashed the New York Daily on his subordinates.

"800 million US dollars, 800 million US dollars, not including laboratory construction and equipment investment! Why are you not as good as a minor child!"

"Mr. Smith, Imipenem has reached the biological test stage, and its effect is very good. After reading the New York Daily, we called the patent offices of various countries as soon as possible. The biologist named Li Zheng did not Registered a carbapenem antibiotic patent." Mr. Brown kept wiping the fine sweat on his forehead.

Imipenem is a key project of Merck and completed the first phase of core patent registration seven years ago. However, in the past seven years, drug trials have progressed slowly and the drug has not been on the market for a long time. Seeing the dawn is ahead, but something like Li Zheng has happened. It was like a three-kilometer race, and ran to the finish line clearly, but found that the first place was already waiting for him at the finish line. This kind of sorrow is really uncomfortable.

What's more, Merck has invested nearly one billion US dollars for the imipenem project. In the past nine years, if Li Zheng's drug is to be marketed first, their losses will be immeasurable.

"Perhaps that scholar does not intend to register a patent..." Mr. Brown's voice was a little weak.

Smith's cup was smashed to the ground, "Aris Brown, when will you learn to place your hopes on others? Merck does not need such a weak person!"

"Please come over, Mr. Kent, I have something to discuss with him. Also, let the secretary's office contact Li Zheng's laboratory, I think I need to talk to that genius in person." Smith rubbed his temple and said.

Brown nodded repeatedly, and quickly walked out of Mr. Smith's office.

A week later, Smith and Kent boarded the plane to Xiangjiang, and the British BBC People of the Century program officially sent an invitation letter to the Li Zheng laboratory. At the same time, six of the nine people who had not been injected with antibiotics in Mary Hospital Announcing that the rescue was invalid and died, the three of them survived with a strong willpower, but left a lifelong sequelae.

"Teacher, congratulations on leaving the hospital!" Li Zheng holding a bunch of carnations, together with the professors of Xiangjiang University, came to pick up Xu Mingsheng from the hospital.

Xu Mingsheng's injury is recovering well. After the leg surgery, although he still can't move freely, he can walk on crutches for a while every day.

"Hahaha, this is the first time I have received flowers after living so long! Li Zheng, thanks to you this time. You are my savior!" Xu Mingsheng was helped by Chen Sufen and sat in a wheelchair.

"Teacher, you are serious. You have already made a good start on this subject. I just continue to follow your ideas."

Xu Mingsheng waved his hand, "Don't shame me, thinking... if organizing materials is also thinking, those who are under my research one and two will be able to stand alone."

Professor Wang laughed, "Old Xu, you should thank Li Zheng, or else, your funding might have been distributed by these old guys."

Xu Mingsheng raised his eyes when he heard this, "Go go! Let me cut my budget!"

There was a burst of laughter in the ward, and while everyone was talking and laughing, suddenly a burst of sorrow and joy came from outside the window. The sound of crying, crying and cursing rang together.

"What's wrong outside?" Xu Mingsheng asked, frowning.

Chen Sufen poked her head out and took a look, the expression on her face suddenly froze.

At the entrance of Queen Mary Hospital, rows of wreaths blocked the entire gate of the hospital. Several family members of the patients were standing in the middle of the gate holding the patient's remains.

They shouted loudly: "The Queen Mary Hospital kills people, no medication!"

The tidy slogans accompanied the cry of the woman and the girl, which attracted the attention of passing pedestrians.

"Old Xu, you have a chat with them, I'll go out first." Chen Sufen said with a strong smile.

Xu Mingsheng patted her hand, "Go, you don't need to worry about me."