Good luck! This village is full of billionaires

Chapter 180

End of May.

United States, New Jersey.

Johnson & Johnson Corporate Headquarters.

Frye took a document and knocked on the door of CE~O's office.

He handed the document to CEO Alexander and reported: "BOSS, our branch in Xia Guo has privately contacted hundreds of Alzheimer's recovery.

These Alzheimer's patients are recovering and have previously participated in Rainbow Manna - Capsule clinical trials.

By observing their physical condition.

We found that the new drug does have a significant effect on Alzheimer's disease. "

Alexander frowned as he flipped through the documents in detail.

Since 1998, the world's top pharmaceutical companies such as Johnson & Johnson, Roche, Pfizer, Eli Lilly, Merck, Bayer, and AstraZeneca have invested more than $600 billion in R&D in the field of Alzheimer's disease.

But the vast majority of the funds have been lost.

Most of the new drugs developed have failed in the first phase of clinical trials.

The difficulty of new drug research and development is comparable to that of climbing to the sky!

The reason why these pharmaceutical companies are so persistent.

There are two main reasons.

First, there are 50 million people living with Alzheimer's disease (AD) worldwide, and the field is a blue ocean from an economic point of view.

Second, the only disease that lacks effective treatment among the top 10 causes of death in the country is Alzheimer's disease.

Rainbow Pharmaceutical Co., Ltd. has now developed a new AD drug with remarkable efficacy.

This undoubtedly means:

In the future, the field of Alzheimer's disease will be respected by Rainbow Pharmaceutical Co., Ltd.!

The world's major pharmaceutical companies.

None of them can compete with it!

Come to think of it.

Alexander knocked on the table and said in a condensed voice: "The market in the field of Alzheimer's disease is more than a trillion dollars. It's really unwilling to be taken away by Rainbow Pharmaceutical Co., Ltd. like this!"

Frye reported, "Boss, there's bad news from the lab.

The phase I developed a BACE inhibitor that failed in phase I clinical trial.

The company lost $3.6 billion in the development of the drug.

If you include the bapineuzumab monoclonal antibody drug that failed in the 2012 clinical trial, the company has lost more than $6.5 billion in the field of AD in the past five years!"

Hear this.

Alexander sighed.

$6.5 billion in R&D expenses has been wasted.

Johnson & Johnson is, of course, the world's No. 1 pharmaceutical company.

But it can't afford to lose money in drug research and development for many years.

And so on.

As the CEO, I'm afraid he won't be able to sit still!

Johnson & Johnson is a leader in the pharmaceutical industry.

As the CEO of the company, he can be called the strongest "worker" in the medical industry, with an annual salary of 29.58 million US dollars.

If you lose this position.

In the future, I will never be able to find a job with a satisfactory salary.

Alexander asked, "How is the progress of drug research and development for companies such as Huirui, Roche, and Eli Lilly?"

Frye hurriedly replied: "Huirui has announced that due to the high cost of research and development and poor efficacy, it will no longer try to develop new AD drugs.

Roche's previously developed gantenerumab monoclonal antibody drug failed in phase 1 clinical trials.

Eli Lilly's previously developed A inhibitor failed in a phase 1 clinical trial.

Merck & Co., Ltd.'s previously developed BACE inhibitor verubecestat has been discontinued.

AstraZeneca's previously developed BACE inhibitor 1anabecestat failed in a phase 1 clinical trial.

Biogen/Eisai's previously developed drug aducanumab failed in a Phase 1 clinical trial. "

The voice fell.

Alexander's mood was a little better.

Make innovative drugs, nine deaths.

To be an innovative drug for AD, one hundred deaths and one death.

At present, the world's top pharmaceutical companies have not been able to develop AD drugs.

At the very least, he, the CEO, will not be dismissed.

As for the appearance of the rainbow manna capsule, it is a "non-war crime".

Who would have thought.

Rainbow manna capsules, instead of taking the two R&D routes of BACE and A, choose to start with the intestinal flora skirt.

Rebalance the intestinal flora.

It sounds like a lot of difficulty.

But Rainbow Pharmaceutical Co., Ltd. has really done it!

Moreover, the total cost of enterprise research and development seems to be three or four billion yuan.

Not even $50 million......

At this time, Fry proposed: "BOSS, since we have developed a new drug for AD, it is better to change the direction of research and development to a generic version of rainbow manna capsules." What do you think?"

"Generic ......"

Alexander laughed at himself: "As a leading enterprise in the pharmaceutical field, we actually go to make generic drugs of Rainbow Pharmaceutical Co., Ltd., which is too cheap." "

The so-called generic drugs, that is, copycat drugs.

However, it is very difficult for generic drugs to be marketed.

The FDA of the United States has determined that generic drugs must be exactly the same as other generic patented drugs in terms of active ingredients, dosage, safety surname, efficiency, effect, side effects, and disease.

Johnson & Johnson is the world's No. 1 pharmaceutical company.

There's no reason to be a generic version of rainbow nectar!

"Have you forgotten the protection period of the new drug?"

Alexander pouted and said: "Rainbow Manna Capsule has initiated new drug approval to the Xia National Drug Administration.

Once the new drug is on the market, Rainbow Manna Capsule can obtain the new drug certificate. (If you read a violent novel, go to Feilu Novel Network!)

What they have obtained is definitely a Class I new drug certificate, and the new drug protection period is 12 years.

In other words, in the past 12 years, no pharmaceutical company will be able to make generic drugs for rainbow manna capsules!"

Hearing this, Frye came back to his senses.

New drug protection refers to the protection given by the state after the research and development of new drugs.

In the past, a pharmaceutical company spent a huge amount of money to develop new drugs with remarkable efficacy. []

Other pharmaceutical companies have rushed to develop similar drugs.

Over time, similar products are competing to reduce prices, and profits are getting thinner and thinner.

To this end, countries around the world have formulated corresponding policies for the protection of new drugs.

Internationally, the protection period of new drugs is as long as 20 years.

Suddenly, Fry said, "Boss, if I'm not mistaken.

The protection period of Xia Guo's new drugs cannot be managed in our country.

As long as the rainbow manna capsule, there is no new drug certificate from the FDA.

We can develop similar generic drugs!"

"That's right!"

Alexander said bluntly: "Even if we start generic research and development now, we will need phase clinical trials, phase phase clinical trials, phase phase clinical trials.

At this time, Rainbow Pharmaceutical Co., Ltd. has obtained the FDA New Drug Certificate.

In terms of time, we simply don't have time to make generic drugs!"

"Knock knock!"

Linna, the secretary, hurriedly knocked on the door and came in.

She took a document and said to Alexander: "BOSS, it's not good! Rainbow Pharmaceuticals Co., Ltd. held another press conference to announce that hundreds of new drugs have passed phase clinical trials and are initiating new drug approvals. "

Alexander took the document and looked at it, and was stunned.

I saw that there was dense new drug approval information on it.

The world's first drug for the treatment of a variety of rare hyperammonemia, rainbow acid dispersible tablets, was approved by the Xia Drug Administration!

The world's first drug for the treatment of type 1 hereditary tyrosinemia, rainbow nitisinone, was approved by the Xia National Drug Administration!

The world's first drug for the treatment of relapsed or refractory multiple myeloma, Rainbow Igta-cel Injection, was approved by the Xia Drug Administration!

The world's first targeted drug for the treatment of diffuse large B-cell lymphoma, Rainbow Vepotuzumab for Injection, was approved by the Xia Drug Administration!

......

The world's first targeted drug for the second-line treatment of late-stage gastric cancer, rainbow ramucirumab, was approved by the Xia Drug Administration!

The world's first drug for the treatment of cholestasis in patients with Alagilli syndrome, Rainbow IBAT Inhibitor Oral Liquid, was approved by the Xia National Drug Administration!

The world's first oral targeted drug for the treatment of late or metastatic non-small cell lung cancer in the EGFR department, Rainbow Moboxetinib Succinate Capsule, was approved by the Xia Drug Administration!

......

The world's first drug for the treatment of HLH refractory inflammatory syndrome, Rainbow imalumab, was approved by the Xia Drug Administration!

The world's first biopharmaceutical covering the indications of lupus erythematosus and lupus nephritis, rainbow belimumab, was approved by the Xia Drug Administration!

The world's first factor Xa anticoagulant inhibitor for venous thrombosis in children and adolescents under the age of 18 - rainbow varoxaban tablets was approved by the Xia National Drug Administration!

......

Alexander, briefly skimmed through.

He was surprised to find that there were 500 new drugs on the document.

The most exaggerated.

These new drugs are all unique and innovative drugs.

Frye, the assistant on the side, leaned over to take a look.

He asked inappropriately, "Boss, what are we going to do next?"

"Let me think about it. "

Alexander, waved his hand weakly: "So many new drugs come out, it is undoubtedly a nightmare for all pharmaceutical companies in the world! "

"Yes, Boss!"

Assistant Frye and Secretary Lina nodded and turned to leave.

......