I can extract side effects

Hangzhou, a street in Jianggan District.

Chen Jianfeng rode an electric bike through the cold wind, and soon returned to the rented community.

He wrapped himself up tightly and wore gloves on his hands. He locked the electric car and charged it, and dragged his tired body back home.

It was already 11 o'clock in the evening, and the food was simmering in the rice cooker. He took off his hat and gloves silently, and started to eat the food with big mouthfuls.

The wife came out of the bedroom, poured a cup of hot tea, put it in front of him, and turned the cup carefully so that the gap on the top did not face him, and then smiled: "How is today? Are you tired? Tomorrow What kind of food do you want to eat?"

Chen Jianfeng swallowed a mouthful of rice, took a sip of tea from his cup, and breathed out with difficulty: "That's it, just eat whatever you want."

He was only in his early thirties, and his temples had begun to turn gray. He looked as old as he was in his forties. After a day of hard work, he looked even more tired and vicissitudes.

"How are Nini and Xiaojian today?" He asked while eating.

The wife's face was suddenly clouded with sadness: "It's still the same, I'm so weak, I can't move in bed, I can only breathe with a ventilator, I'll take care of it at home, don't worry."

Chen Jianfeng nodded, stopped talking, and started to eat.

The wife hesitated to speak, and finally said after a while: "Have you thought about it? I'm going to see a doctor tomorrow. Which child will be given medicine?"

Chen Jianfeng didn't speak, and silently ate all the food in the bowl. He finished every grain of rice very carefully, not wasting any grains.

The wife's voice was already a little choked up: "You talk, you have to make a decision, and we look down on the two children, so we can only choose one."

Chen Jianfeng was immediately upset, but he couldn't get angry, so he could only ask in a muffled voice, "Then what do you say?"

"How can I be partial as a mother, my son and daughter are all meat that fell from me, I can't make a decision."

Chen Jianfeng said irritably: "Aren't you talking nonsense? Is it easy for me to make this decision? Can we talk about it tomorrow?"

The wife suddenly raised her head, her face full of expectation: "Why don't you borrow some more money so that both children can use the medicine?"

Chen Jianfeng was silent for a while, and then said with difficulty: "It may be a bit difficult. We already owe 400,000 yuan in debt. Although the folks in the village have not pursued the debt for the time being because of the child, I am embarrassed to borrow it again."

"You also know that I am the only one working in the family now, and the money I have saved is not much except for living expenses. I don't know that the debt can only be paid off in the year of the monkey, so I have to save 60,000 yuan for the treatment of the child, so for the time being I can choose one."

The wife squeezed out a bitter smile: "I know, it's not easy for you. I wish I had known not to want Xiaojian."

"It's okay, as long as one child is better, he can grow up, and you can relax too. At that time..." Chen Jianfeng said it several times, but he didn't say the rest.

Maybe he is not sure in his heart what will happen to his bleak family in the future.

The wife sighed: "What are you thinking so much about? Otherwise, let's treat Nini first, and then send it back to the old man to take care of her, and go to school by the way, so that I can spend a little more time and see if I can find something to do. If you earn tens of thousands, you can save Xiaojian again."

Chen Jianfeng hesitated for a while, and said with a wry smile: "Okay, I'm going to become an old man, and I probably won't be able to hold my head up in the village in the future."

His wife glared at him: "So what, human life is at stake, let them come to ask for debts, see if I don't scold them all back."

Chen Jianfeng shook his head dumbfounded, got up and walked towards the bedroom: "I'm going to see the child."

There are two beds side by side in the bedroom, squeezing the space to the brim. One bed is where the husband and wife sleep, and the other bed is where two children, a man and a woman, are lying.

Both children are on ventilators, and the boy is less than two years old and has already fallen asleep.

The girl was about four years old. When she saw him, her eyes lit up immediately, and she blinked slowly at him.

Chen Jianfeng knew that it was his daughter who was greeting him. He walked over and held her hand. Looking at her clear eyes, he felt a sense of powerlessness in his heart.

This emotion has never been so strong as at this moment, and he feels that he is really useless.

Logically speaking, it is a happy event for any family when a person reaches middle age and has both children.

But Chen Jianfeng's family is different. Both he and his wife are carriers of the SMA gene.

SMA is a recessive inheritance, and people who carry the disease-causing gene may not necessarily show symptoms of SMA.

Studies have shown that 98% of SMA children, their parents are carriers, and the remaining 2% of children are caused by new mutations.

So neither of them knew that they still had this gene, so it was an instant tragedy.

Four years ago, my daughter Nini was just born. She was fine at first, but when she was more than 1 year old, his wife found that she still refused to walk on the ground, so she took her to the hospital. After repeated diagnosis, she was diagnosed with the rare disease SMA.

"Your daughter can live up to four years old. Go home and take good care of her. This disease is terminal and there is no cure." The doctor's words at that time still echoed in his ears from time to time.

Chen Jianfeng was stunned at the time. After recovering, he took his daughter to various hospitals in the south of the Yangtze River, and even traveled across the country to seek medical treatment, but was told the same result time and time again.

In the end, he spent all his savings and even incurred a debt of more than 400,000 yuan.

But not only did my daughter not improve at all, she even gradually lost the ability to exercise her lower limbs, and her upper limbs also became weaker. The deformity of her spine has become more and more serious now, and she even needs to rely on a home ventilator to assist her ventilation.

During his long treatment career, he knew that it was impossible for his daughter to get better. After consulting local doctors, he learned that if he had another child, the chance of suffering from the disease was only 25%.

If the child is healthy, they will be able to take care of Nini after a hundred years.

So, the couple decided to take a gamble for Nini.

Two years ago, his son Xiaojian was also born, however, unfortunately, the tragedy repeated itself.

When he was one year old, Xiaojian was diagnosed with SMA again.

The couple only learned after giving birth to their son that about one in 50 people is a carrier of the SMA disease-causing gene. As long as the second child is prenatally checked or screened for carriers of high-risk groups with family medical history, new infections can be effectively blocked. Cases.

But the couple are both farmers, and they didn't know that prenatal genetic testing could be done for this disease. Moreover, there were no corresponding testing institutions in the local area at that time, so they could only swallow this bitter fruit with tears.

Later, he brought his family to Hangzhou and earned money by delivering food. At first, he thought about paying off his debts.

The children's future is no longer what they expected. Anyway, the doctor said that both children will not live to be four years old.

Xiaojian's illness seems to be even more serious, and now not only can't move, he can't even get off the ventilator completely.

But the intelligence and sanity of the two children are normal, and they can still interact with the couple to a certain extent.

Such a scene undoubtedly made him sad and painful.

Three months ago, when they went to the hospital for an examination again, the doctor told them a good news.

A drug for the treatment of SMA, Biogen’s Nosinagen Sodium Injection has entered the medical insurance, and the price has dropped to 30,000 per injection. In addition to the medical insurance reimbursement, the first year’s self-payment is about 60,000 yuan, plus charity donations. After waiting for some relief, it is estimated that 20,000 yuan per year will be enough.

Upon learning of this, the couple were ecstatic and finally found an affordable SMA drug.

They also asked at that time whether there was any medicine that could completely cure the disease.

There is indeed a 'miracle drug', which can provide long-term relief or even cure patients with just one intravenous injection.

However, it was a sky-high price. The figure of 14 million made the couple dumbfounded and speechless for a long time.

This astronomical figure has exceeded the limit that two honest Bajiao rural people could imagine.

It may be strenuous for them to count the zeros behind them.

You know, the tens of thousands of yuan of medicine is a bit heavy for them.

And they also have two children, so the cost of treatment has to be doubled.

No matter how hard and tired a child is, he can provide for it, but for two children, the first year is 120,000 yuan, so how can he get this money.

After thinking about it, the two hesitated again and again, so they decided to save a child first, but they never decided which one to save.

In fact, Chen Jianfeng knew in his heart that his daughter was already four years old, and if she didn't take medicine, she probably wouldn't survive this year.

The first quota is definitely for the daughter. When the daughter is well, she will be sent back to her hometown to be taken by her parents to go to school and live normally.

Later, I asked my wife to find another part-time job to see if I could save another 60,000 yuan to treat my son as soon as possible.

In any case, at least life is more bleak than before, and there is finally a glimmer of hope.

Chen Jianfeng stayed with his daughter for a while, then went to bed and rested.

Not long after he lay down, his wife rushed in suddenly, shaking his body frantically, calling out in a low voice.

"Wake up! Wake up!"

Chen Jianfeng opened his eyes in a daze, a little irritated: "What's the matter, can't we talk about it tomorrow?"

The wife handed over her mobile phone, and the screen displayed the picture of the WeChat chat group.

This is the patient group of SMA patients, where the family members of the patients will often exchange some treatment information and help each other. Chen Jianfeng's residence and work were introduced by an enthusiastic patient, which made him have a place to stay when he came to Hangzhou .

Chen Jianfeng's eyes were still a little blurry, and he struggled to read the news on the screen.

One by one, there are many.

Most of them are messy speeches from group friends, and there are a few links.

He didn't even look carefully, just turned back up.

Suddenly, a piece of news came into view, which made him tremble, and he sat up straight.

"Shocking news! Sanqing has developed a gene therapy drug that can completely cure SMA, and is now soliciting patients for free clinical trials. Interested patients can apply for it."

He opened his mouth wide and looked at the news, unable to recover for a long time.

His wife pinched him severely to wake him up.

As if his ass was on fire, he immediately jumped up from the bed and rushed out of the bedroom.

The wife followed and asked in a low voice: "Look at the other news, should we ask the doctor tomorrow, or what? Hey, it's the middle of the night, and I don't know what to do. I'm so worried. "

Chen Jianfeng held the mobile phone in both hands, his fingers trembling slightly, he quickly read through all the news from the group of friends, and finally figured out the general situation.

It turned out that the domestic pharmaceutical giant Sanqing Pharmaceutical announced the news today, and the couple were too busy to see the news in the group for a while.

It wasn't until midnight when everyone was discussing in full swing that his wife saw it and quickly woke him up.

Sanqing has published its contact information and clinical partner hospitals on its official website.

And the patients in the group also asked the doctor and got confirmation.

Chen Jianfeng looked at it for a while, and then made a decision: "We will go to the First People's Hospital of Kunming tomorrow morning to apply for clinical trials for the children, and buy the fastest high-speed train. Don't worry, Hangzhou and Kunming are very close. Hour high-speed rail, in time."

The wife was so surprised and happy that she almost jumped up.

Chen Jianfeng walked over suddenly and hugged her tightly.

He whispered in his wife's ear: "The children are finally saved."

"Woooo..." His wife buried her head in his arms and sobbed silently.

She kept her voice low so as not to disturb the children.

Although it was crying, there was no sadness in it, only endless joy.

And a strong release after a long period of emotional repression.