I can extract side effects

After the successful development of the thalassemia gene drug, the long-suppressed mood of patients around the world broke out completely.

Some wealthy and powerful patients contacted Sanqing through various channels and asked how to obtain the medicine.

Faced with more and more applications, Weikang urgently held a meeting of the R\u0026D department to discuss how to deal with it.

The gene medicines for single-gene genetic diseases developed by Sanqing before are all rare diseases, and the number of patients is very small. There may only be hundreds or thousands of cases in the world. Generally speaking, the demand is not large.

Moreover, the genetic points that are mutated or missing in these diseases are very similar. As long as a drug is developed, most people can be treated.

But thalassemia is different. First, there are many patients. There are 20,000 severe cases in China alone, and even more moderate and mild cases. If you add a large number of overseas patients, the number is quite huge.

This is no ordinary chemical, everyone just needs to take the same generic pill.

More importantly, thalassemia has hundreds of mutated gene segments, and the mutated gene segments may be different for each person. It is undoubtedly an impossible task to make genetic medicines for everyone.

For such a complicated situation, Wei Kang didn't have a particularly good way to deal with it for a while, so he could only choose patients.

In the office, Wei Kang crossed his hands on the table and looked at the three generals in front of him.

"Do you have any good ideas?"

Chen Yiqing, Wen Renlong, and Tang Que looked at each other and shook their heads slowly.

After a moment of silence, Tang Que said: "Thalassemia is different from other monogenic diseases. With the current gene editing technology, we need to design the inserted gene segment for each patient. This is a heavy workload and takes a long time. , doomed not to be popularized quickly.”

Chen Yiqing sighed and said: "This drug is very special, and it may only benefit the rich. Ordinary patients may only use traditional treatment methods. We really have more than enough energy."

Wen Renlong nodded: "This is the real world. The best way is to prevent it. If many genetic diseases can be detected during pregnancy, it can avoid dragging the whole family into the quagmire."

Wei Kang frowned and said: "Money is not a problem. Now I have received many applications from patients. They asked to participate in clinical trials, saying that they would not hesitate to pay any price. The point is, they are all very rich, or in high positions, and they can fully afford it." Customized treatment fees."

Wen Renlong shrugged, and said indifferently: "Then promise them, anyway, they have money, can't these medical expenses just cover R\u0026D and clinical expenses?"

"However, we still have some applications submitted by domestic patients. This part of the demand cannot be ignored, and our clinical trials can't all accept rich people from abroad. That's really unreasonable."

Tang Que hesitated to speak: "Boss, there is a certain number of places for clinical trials, and the number of people can't be too many."

Wei Kang thought for a moment and said: "Aaron is right. Anyway, the rich have money. We can ask them to pay huge fees, and then use the money to benefit domestic patients."

"But you can't do it too directly, otherwise they are all patients participating in clinical trials. Why do some have to pay so much money and some don't? This seems unfair."

Wen Renlong curled his lips and said: "Didn't the prince of the desert country pay the sponsorship fee last time? This excuse is very good. These days, rich people like to sponsor scientific research activities, which is normal. If I have a tens of billions If you are rich, you will definitely fund the research and development of the elixir of life."

Chen Yiqing interjected, "Paying sponsorship fees can only be done during the research and development stage. What will happen when it goes public?"

"The price must be transparent once it's listed. How can we still collect sponsorship fees? If the price is too high, the poor still look down on it. If it's too low, it's not worth the loss. Shouldn't the people in Lao Tang's laboratory be exhausted?"

Wen Renlong strongly agreed: "There is indeed a need for a screening mechanism, especially for foreigners. To put it politically incorrect, what does their life and death have to do with us? Why do we have to exhaust Old Tang to treat them?"

"They have a way to treat thalassemia, but they can't be cured. In this regard, they are already far better than the poor. The real poor can't afford blood transfusions and iron removal every year. .These are the real users of our drugs.”

"If it wasn't for the sake of money, I would not agree to exhaust Old Tang to death."

Tang Que's face was darker than the bottom of the pot, and he said coldly: "There is no end, who said I'm going to die of exhaustion?"

Wen Renlong chuckled and said: "I know, I know, you have a group of younger brothers, this matter will definitely not tire you."

This topic was about to go off track, Wei Kang quickly pulled it back.

"Well, let's set up a charitable foundation for this kind of niche or complex genetic medicine. The funds raised are mainly used to pay for research and development and clinical expenses, so as to ensure that we can not lose money from drug development to marketing. After listing, we can also help the poor. Patients give medicines for charity.”

"The wealthy who want to treat diseases have to donate money to apply for clinical trials. After the listing, complex conditions like thalassemia can be sold at a very reasonable price, so there is no need to worry that the poor will not be able to afford it."

Clap clap!

Wen Renlong immediately applauded: "Great, I have long since disliked those rich people. They are so rich, so why sell them so cheaply?"

"In my opinion, in the future, Sanqing will check the assets of patients when selling medicines, and then collect money according to the proportion of assets. In this way, the richer people will have to pay more for their health, and the poor will not have to go bankrupt when they see a doctor. It is fair to everyone. That's the real health tax."

Wei Kang couldn't laugh or cry: "Stop messing around."

However, his heart was moved. This suggestion seemed to sound reasonable.

When people get old, various diseases will emerge. In order to maintain health, people need to spend money on maintenance or treatment. Even if they are not sick, they must experience it frequently and prevent it early.

Isn't this a kind of health tax in a sense?

With the development of science and technology in the future, whether it is treating diseases, organ transplants, or even maintaining youth, it will cost a lot of money. As long as everyone can live a healthy life to the end of life, someone will definitely be willing to spend this money.

But in order to truly popularize technology and benefit all mankind, it is certainly impossible to make it expensive and unaffordable.

Otherwise, it will inevitably lead to a situation like that of end-producers in science fiction, and this is not a good thing for pharmaceutical companies, because it is impossible for pharmaceutical companies to develop drugs that can only be used by a small number of people.

It is not what pharmaceutical companies want to let everyone die of illness. It is the dream of pharmaceutical companies to make money from every patient.

In this case, a reasonable distribution plan must be designed.

The rich have plans for the rich, and the poor also have solutions for the poor. Everyone is happy. This is the situation that pharmaceutical companies like.

Just like the property tax in Eagle Country, isn't it collected according to the market price of the house?

So why can't such a valuable health tax be collected according to assets?

Maybe, in the distant future, no matter the poor or the rich, as long as they spend a certain amount of money every year according to their own income, everyone will be able to maintain youth when they get old, replace any organ that is broken, and take medicine to cure it when they are sick, and be healthy and healthy live to 120 years old.

That may not be such a bad thing.

However, things could also go in the other direction.

Maybe I have to work until I am 100 years old before retiring, and the mortgage can be backed for 70 years.

Thinking of this, Wei Kang couldn't help but tremble in his heart, this is really too scary.

He quickly dispelled these messy thoughts in his mind, and said seriously: "Very well, that's it. In the future, if you want to apply for Sanqing drug clinical trials, rich people have to donate at least 1 million US dollars to the Sanqing Charity Fund to get in the queue." Qualifications."

"Of course, we have always given preferential treatment to our compatriots. The rich in China only need 1 million RMB."

"A local tycoon like Prince Salman who donated 10 million US dollars at a time is our chief guest. It is fine to develop new drugs for him. After all, his money is enough for him alone. After the drug is released, it will save many people."

"With a few more rich people who are as generous as him, we will have more funds to develop more new drugs. This is a great thing. Maybe patients all over the world can rely on these rich people to overcome all diseases."

Chen Yiqing thought of many of his classmates who stayed in Yingguo, and couldn't help asking: "Is this overseas Chinese considered domestic or foreign?"

Wei Kang was taken aback: "If you still have Chinese nationality, of course you are considered a domestic rich person. If you are already a foreign nationality, unfortunately you can only be regarded as a foreign rich person. But we also have preferential treatment for them. For Western rich people, 1 million The US dollar is only the threshold, they have to queue up according to the donation amount, if they are Chinese, they don’t need to queue for 1 million US dollars.”

Wen Renlong applauded again, grinning from ear to ear: "Boss, this is very capitalist, well done!"

Chen Yiqing also had no objection, and agreed: "Very good, it is very popular for rich people in the West to donate to charity, and they must be willing to open their wallets generously."

Tang Que snorted coldly: "That's true. With so much money, I have to work hard to get motivated."

After speaking, a rare smile appeared on his face.

The next day, the Sanqing Charity Foundation announced its establishment.

This is an independently operated charity organization that accepts donations from all over the world. The details of operations and donations will be published on the website on a monthly basis to be open and transparent.

After the establishment of the foundation, the first donation announced was Prince Salman’s 10 million US dollars, and the destination is also very clear. It will be used to pay for the research and development of thalassemia gene drugs, as well as the first and second phases of clinical trials.

Of course, 10 million US dollars is still not enough for the cost of clinical trials, so those domestic and foreign rich people who applied to participate in clinical trials received a very polite reply email.

"Dear Mr. xx, it's a pity that the clinical trial is currently going on with difficulty, but there is still a big funding gap. If you are willing to contribute to the drug's release as soon as possible, it will greatly promote the smooth progress of the clinical trial." , as a thank you, you will have the priority to obtain the quota for clinical use of this drug."

"Please click the link below to view the donation process. After receiving your remittance, we will arrange someone to contact you for subsequent clinical application. Thank you for your letter! I wish you good health forever!"

*****

In Camel Country, a rich man in the Middle East wearing a headscarf opened his mailbox and saw the long-awaited email.

He happily clicked on the link, and found that the donation threshold is 1 million US dollars, and as long as you donate, you can enter a waiting list.

One of the characteristics of a rich man in the Middle East is that he is extremely wealthy and arrogant. He only thought for a second, then waved his hand and donated 10 million US dollars.

The website is very considerate, as long as you make a donation, you can see your ranking on the waiting list.

The hijab tycoon was very satisfied to see his ranking soar into the top three in an instant.

There are 100 quotas for the first and second phases of clinical trials.

He snorted softly, feeling refreshed all over.

This local tycoon is also familiar with Prince Salman. He has asked the prince carefully about the whole treatment process, and he is looking forward to this gene drug.

Although he only has a mild Mediterranean disease and only needs occasional blood transfusions, it is not as serious as Prince Salman.

But for this genetic disease, it is best to treat it early, because he learned from the prince that the treatment process is very complicated and needs to be tailored for the defective gene.

Because of this, Sanqing currently has no motivation to go public abroad, so if you want to treat it, applying for a clinical quota is the best result.

Anyway, he is not short of money, and it is quite a bargain to buy health insurance for 10 million US dollars.

If this drug is really not on the market overseas, then he will be in trouble.

After all, he was quite envious of Prince Salman posting pictures of himself surfing on Twitter every day after he regained his health.

*****

In the Eagle Kingdom, Solomon, a rich man of Isaac's descent, also received this reply email.

He snorted coldly, clicked on the link, and saw the request for a donation of 1 million US dollars, and his face twitched immediately.

"It's too much. It's a bunch of greedy guys to sell clinical trial quotas naked. It's a shame for pharmaceutical companies."

He was so angry that he directly closed the webpage: "I have a million dollars, and I can go for a direct bone marrow transplant."

However, after thinking about it carefully, Eagle Country may not be able to afford a million dollars for bone marrow transplantation, and it is difficult to find a bone marrow that matches him. There is also the possibility of rejection and infection. This one million dollar donation instantly becomes tempting People got up.

He pinched his nose to donate $1 million, and landed on a new page showing a waiting list.

100 places, he ranked last.

Solomon suddenly became furious: "Asshole, why is this happening? I have already donated 1 million, how could I be the last one?"

He immediately realized that it was obvious that the 1 million was only an entry level, and the 100 list must be ranked according to the amount of donations. If you want to rank high and get clinical places as soon as possible, you must donate more.

"Shit, I will never let you make such black-hearted money." Solomon clenched his fists, with veins popping out of his forehead, and turned off the computer directly.

However, after a few days, the incident was still on his mind, and he was angry and annoyed when he thought about it.

Suddenly, he remembered that an acquaintance, like himself, also applied for Sanqing's clinical trials, and it happened that the other party was also rich.

So he called and asked.

"Hehe, Solomon, your call happened just in time. I have already received a call from Sanqing. They have arranged a clinical experiment for me. I have already booked a first-class cabin for tomorrow night."

Solomon was shocked and angry: "How could you be so fast? How much did you donate? Why didn't I receive a call."

The other party's tone was very surprised, and then suddenly realized: "I am different from you. I am very old, and I really want to experience the feeling of health early, so I donated 8 million US dollars from the beginning. What, you cheapskate, Have you committed the old habit of being stingy again?"

"I sincerely advise you, in fact, the price is not expensive at all. Do you know how much it costs for allogeneic bone marrow transplantation in Eagle Country? My doctor at the Mayo Clinic told me that if you successfully find a matching bone marrow, it will cost three months." Millions of dollars, if it doesn't go well, we can only wait indefinitely."

"So, if you only pay one million, your chances will be very small. Only by increasing your chips can you get more opportunities. Obviously, we all know how to use money reasonably, but you haven't figured it out yet."

After hanging up the phone, Solomon was flustered for a while, and opened the page again.

Gritting his teeth, he transferred another 1 million US dollars, but the ranking remained unchanged, sitting firmly at the bottom.

He was suddenly a little out of breath, and continued to transfer money while cursing.

With $3 million, his ranking finally slowly began to rise.

With $5 million, he's ranked in the top 50.

Solomon wiped the cold sweat from his brow, only to feel his heart ache like a knife.

He looked at the ranking and couldn't do it anymore.

"The top fifty should be enough. Even if you don't call me tomorrow, at least you will have news next week."

However, he waited and waited and waited and waited for a full month without any call.

Angrily, he opened the webpage and took a look, his eyes went dark, and he almost fainted.

He actually fell to the last place again.