I Can See Health
Chapter 588 The magazine’s reply
Remember [new] in one second! The first area in my heart is the doctor’s office.
When everyone heard Lu Chen's words, they were slightly stunned at first, and then shook their heads.
"It's impossible, the patient has chest pain!"
"I have never seen a patient with this kind of electrocardiogram without any disease..."
"Lu Chen, you must at least rule out other diseases before considering physiological conditions, right?"
…
Everyone was talking a lot, and they were not very supportive of Lu Chen's "disease-free theory".
In medicine, there is a default rule that consideration of a patient's physiological abnormalities needs to be done after all possible diseases have been ruled out.
For example, for a patient with proteinuria, you may need to rule out kidney disease before considering physiological proteinuria. (Physiological proteinuria can be seen in changes in body position, strenuous exercise, high temperature, etc.)
It is impossible to consider that proteinuria is caused by physiological conditions from the beginning.
Su Rui on the side also looked at Senior Brother Lu Chen very curiously.
She had been following Lu Chen for a while, and knew that her senior brother's character was definitely not the kind of person who would make random decisions.
Lu Chen must have his own reasons for saying this.
She looked at Lu Chen quietly, looking forward to his next words.
Lu Chen waited for everyone to finish expressing their opinions, then cleared his throat and said, "Teachers, have you ever seen an electrocardiogram of a black person before?"
As soon as these words came out, everyone was a little confused and shook their heads.
Although Kyoto is an international metropolis, when foreigners come to Kyoto First Affiliated Hospital for medical treatment, they always go to the International Department and rarely come to them.
African medicine is lagging behind, and it is rare to see black doctors appearing at global conferences.
Xiao Shikang was also in the office. He asked aloud: "Lu Chen, do you mean that different races have different electrocardiogram performances?"
Lu Chen nodded, "Yes, actually this is easy to understand. For example, the recommended dosages in many clinical guidelines are different for different races, such as warfarin, rosuvastatin and other drugs..."
Warfarin is an anticoagulant drug. At the same dose, yellow people are more likely to have bleeding complications than white people.
Xiao Shikang frowned, "This is just a drug, it cannot represent the changes in the electrocardiogram. As long as the black man's heart is on the left side and the position in the chest remains unchanged, then the electrocardiogram should not change."
The principle of surface electrocardiography is the technology of using an electrocardiograph to record the electrical activity changes produced by the heart in each cardiac cycle from the body surface.
When everyone heard Xiao Shikang's words, they nodded in agreement.
Lu Chen shook his head. When it came to electrocardiogram and electrophysiology, that was his strength!
"Teacher Xiao, you may have overlooked one thing, and that is the adaptive change of the heart."
Xiao Shikang frowned deeply, "Adaptive change?"
Lu Chen nodded slightly and continued: "Race is one of the main factors causing cardiac changes in exercise adaptation. More than two-thirds of black athletes have repolarization changes in their electrocardiograms."
"Including j-point elevation in the precordial leads (v1~v4) and dorsal upward elevation of the st segment, as well as t wave inversion. In the absence of other clinical or electrocardiographic features of cardiomyopathy, the above electrocardiographic manifestations are normal variations. No further screening is required.”
The black man on Lu Chen's hospital bed was an athlete by profession.
In the office of the Department of Cardiology, everyone found it difficult to digest what Lu Chen said.
"Lu Chen, are you saying that this patient doesn't need any other tests?" Xiao Shikang asked tentatively.
Lu Chen nodded slightly, "No need, it should be a normal physiological change."
"Then how do you explain his chest pain?"
Lu Chen thought for a while and said, "I asked the patient carefully and found that he was exercising strenuously when the chest pain occurred, so I thought the chest pain was most likely caused by exercise."
"This..." Xiao Shikang was stunned and didn't say much.
Those present here are all leaders of the younger generation in the field of cardiology, and they will not easily listen to Lu Chen's words.
One of the residents who had just arrived at the department said, "Lu Chen, is there any literature support for what you said?"
Lu Chen nodded without hesitation: "Of course, it is mentioned in the latest issue of International Athletes' Electrocardiogram Analysis. If you are interested in knowing more, I can send the document to the group."
This document was also found by Lu Chen just now.
There is a "Literature Reading" skill card, and it is very simple to find this kind of literature.
"Lu Chen, post it to the group quickly!" the resident doctor said quickly.
"Okay." Lu Chen smiled and nodded.
Everyone is very interested in this new knowledge.
Especially this theory is completely opposite to everyone’s normal thinking mode!
Medicine is a profession that requires continuous learning and relying solely on experience to treat diseases. Sooner or later, you will be eliminated.
Everyone clicked on the documents Lu Chen posted in the group.
It didn't take long for Lu Chen to notice the prompt that popped up on the system panel.
"Congratulations, I received a +1 thank you from Xiao Shikang!"
"Congratulations, I received a +1 thank you from Su Rui!"
"..."
A series of thank you points, it seems that I have successfully pretended this time.
What makes Lu Chen most gratified is that the completion of the system upgrade has also improved, and he is one step closer to the next upgrade!
…
After finding the correct diagnosis, the next diagnosis and treatment plan is for the black people to decide.
"Dr. Lu, are you saying that my electrocardiogram performance is physiological?" The black man also showed a smile.
In fact, he felt that there was nothing wrong with him, but the doctors at the school hospital were too nervous.
"Well, we rarely treat foreigners." Lu Chen patiently explained, "But we have read the international clinical guidelines and found that about two-thirds of black athletes will have this kind of electrocardiogram performance, so it is a normal physiological phenomenon. , no need to deal with it at the moment.”
"However, if you are worried, we can provide you with further cardiac examinations, such as cardiac ultrasound, cardiac angiography, etc."
The black man quickly shook his head, "Dr. Lu, I trust your judgment. Let's do this. I also have doctor friends in Africa. Let me tell them about the situation here."
"Of course." Lu Chen nodded.
The international guide is just a piece of paper. It would be best if it could be verified in reality.
Subsequently, black people began to contact their doctor friends in Africa.
After a while, the black man came to the doctor's office and found Lu Chen.
"Doctor Lu, you are so amazing!" The black man showed his white teeth. "My friends in Africa said that my situation is indeed common!"
Everyone in the office heard the black man's words and became more convinced of Lu Chen's previous remarks.
I didn't give Lu Chen any thanks just now, but this time I finally gave Lu Chen some thanks.
Lu Chen smiled slightly. This black man has a high emotional intelligence. He knew he would come to the office and praise him.
"In this case, you can be discharged from the hospital."
After all, black people still had to pay for electrocardiograms and blood tests. Su Rui processed a 24-hour admission and admission record and discharged the black people.
…
After dealing with the black patient, the doctor's office in the heart of the first area had a brief moment of tranquility.
Lu Chen was checking the system panel, calculating how long it would take until the next system upgrade.
At this time, the beautiful junior sister Su Rui suddenly approached Lu Chen.
A vague fragrance was refreshing and made Lu Chen's heart skip a beat.
Having been single and solo for so many years, even Lu Chen, a veteran cadre, had a hard time withstanding this test.
"Brother, this black man just gave me an idea." Su Rui said softly.
"Say." Lu Chen concentrated his attention and didn't look sideways.
Su Rui thought for a while and said slowly: "Brother, in the National Natural Science Project you are currently working on, the experimental group is yellow people, and AstraZeneca's experimental group is white people. Actually, if you think about it carefully, there is not much conflict, right? "
Lu Chen looked at Su Rui in surprise, this little girl is pretty good!
It is actually possible to draw inferences from one instance to other cases. From the black patients, it reminds me of the National Natural Experiment Project.
He will definitely be a good candidate for scientific research in the future!
"What should I say about this..." Lu Chen touched his chin. Su Rui's words were correct, but she ignored a very important point. "In your opinion, where is the most developed medical field in the world?"
"Europe, the United States, and Japan." Su Rui said, "Most of the clinical treatment guidelines are written by experts from European and American countries. Our Chinese medical experts are translating them, making slight changes, and turning them into domestic guidelines."
"Yes, that's right." Lu Chen nodded, "Then, under the same conditions, if I study yellow people and AstraZeneca studies white people, who will have the greater influence in the end?"
Su Rui was stunned, "It should be AstraZeneca. However, this will not affect our research results, after all, the research subjects are different..."
"It does not affect our results. However, in this cutting-edge field of science, compared with AstraZeneca, if our research results are slower than theirs, the number of experiments is smaller than theirs, and our statistical methods are lower-end than theirs, then our Do the research results have any international influence?" Lu Chen said slowly.
Su Rui glanced at Lu Chen, "Will everyone say... that we plagiarized or plagiarized?"
"Yes." Lu Chen nodded slightly, "Not only does it have little influence, it is very likely that others will say that AstraZeneca is cheating!"
Although Lu Chen didn't want to think about it, this was the reality.
China's medicine is indeed lagging behind the international level. Although it is catching up non-stop and is already at the forefront of the world in some fields, overall, there is still a big gap between it and powerful countries such as Europe, the United States, and Japan.
Why is Lu Chen trying so hard to catch up with AstraZeneca?
Because if we slack off and allow AstraZeneca to complete the experiment ahead of schedule, the results of his experiment will not make any splash internationally and will only be used for domestic entertainment.
"Brother, when do you think we in China will surpass foreign countries?" Su Rui sighed slightly. Medical students attach great importance to English ability, because most of the top literature comes from Europe and the United States.
Lu Chen was slightly startled when he heard Su Rui's words. More than Europe, America, and Japan?
A seed slowly sprouted in Lu Chen's heart.
Lu Chen murmured in his heart: "Yes, there will be such a day!"
…
Across the ocean.
Harvard Medical School, USA.
As a review editor (peer review expert) of the "" journal, Fan Boyan will be assigned to review one or two papers every once in a while.
As a Chinese, he has been in the United States for many years. Through his own efforts, he successfully became an associate professor at Harvard Medical School.
As a Chinese, this is also extremely rare at Harvard Medical School.
Today, Fan Boyan received another email from the editorial department of "Professor Fan", "Please help Professor Fan review the manuscript."
Fan Boyan happened to be free, so he opened the email.
As a peer reviewer, he has great power to determine the final outcome of an article.
Each paper generally has three peer reviewers. As long as it can get the favor of two experts, it can basically be accepted by the editor-in-chief.
Peer expert review can be divided into single-blind and double-blind. The magazine chooses double-blind, that is, the contributors and reviewers do not know the identity of each other.
"Looking at this English writing habit, it's so authentic. It should be a paper from some European and American university or research institute."
As a Chinese, Fan Boyan is very aware of the English writing habits of contributors from various countries.
Generally speaking, people from other countries, no matter how professional their English proficiency is, their ideas for writing papers are still close to the thinking of their own country.
The paper in front of Fan Boyan, at first glance, was so authentic.
It absolutely cannot be written by someone from another country.
"Hey, this is still a study on dapagliflozin!" Fan Boyan murmured, "Is this another AstraZeneca paper?"
Recently, dapagliflozin has become a big hit in the field of international cardiovascular drugs!
Fan Boyan has also read several papers about AstraZeneca's research on dapagliflozin.
"I remember that there seems to be a laboratory in China that is studying dapagliflozin, and it has published several good papers."
Fan Boyan will be involved in such cutting-edge hot fields.
Especially, this time, the research team of “dapagliflozin” also comes from China!
For Fan Boyan, this was a big surprise.
As a Chinese, although he is in the United States, his heart is in China. He is always paying attention to the consultation in the field of cardiovascular drugs in China.
Fan Boyan threw away the distracting thoughts in his mind and continued reading.
"Hey, something's wrong!"
As a professor and doctoral supervisor in the field of cardiovascular disease, he immediately noticed the anomalies in this paper.
“There’s something wrong with the statistical methods used in this paper!”
It’s not that the statistical method is too bad, on the contrary, it’s great!
For this type of clinical research experiment, such high-end statistical methods are simply not needed.
It only takes a slightly lower level of statistical methods to reach the same conclusion.
Fan Boyan frowned slightly. He paused in reviewing the paper on "dapagliflozin" and instead found the documents previously published by AstraZeneca.
In this comparison, Fan Boyan discovered something unusual.
In previous papers published by AstraZeneca, such advanced statistical methods have not been attempted at all.
How could a "special case" suddenly appear?
"Isn't this paper in my hand published by AstraZeneca?"
Fan Boyan was shocked by this idea in his mind!
If it was not issued by AstraZeneca, then wouldn't it be issued by the laboratory in China?
"When did China dare to engage in this kind of scientific research competition with AstraZeneca?" Fan Boyan still couldn't believe it.
In his subconscious mind, aren't domestic scientific researchers following behind Europe, America and other countries to carry out translation work?
If it was really a domestic laboratory... Thinking of this, Fan Boyan felt a little more expectation in his heart.
…
…
…
Kyoto University First Affiliated Hospital.
A doctor's office in Heartland.
"Lu Chen, you have been in Kyoto for about two months, right?" Xiao Shikang said to Lu Chen.
"Yeah, almost." Lu Chen nodded slightly.
Time flies so fast, half a year of exchange life, one third has passed in the blink of an eye.
"The graduate department in the college requires all the students you come to exchange to submit a summary." Xiao Shikang said, "The main thing is to talk about what you have done in the past two months and what you have gained or achieved."
"Okay." Although Lu Chen is not interested in this kind of thing, he can only carry out what the hospital requires.
Return to the dormitory.
Lu Chen began to prepare the monthly summary.
He heard that the college would also give certain rewards to students with outstanding performance.
The specific criteria for judging are not yet known.
"It's been two months so soon!" Lu Chen murmured in his heart, there was not much time left for them to conduct clinical research experiments!
According to the previous deployment, if he cannot publish a high-scoring SCI paper within two months and prove that he has the ability to compete with AstraZeneca, then he will have no choice but to lie flat!
"Time is running out." At this time, Lu Chen could only look forward to the reply from "" magazine.
As for others in the research team, Ke Yue’s paper has been accepted, which is good news!
As for Gu Xinyue and Wang Zihao, due to lack of experience, the paper they completed together was returned for revision.
The other party did not directly reject the manuscript, but returned it for revision, which also means there is still a chance.
Lu Chen was relatively free for the time being, so he took advantage of this opportunity to help Gu Xinyue and Wang Zihao revise their papers.
…
In the blink of an eye, another week has passed.
The paper that Lu Chen helped Gu Xinyue and Wang Zihao revise was also accepted by the magazine!
For this reason, Wang Zihao was excited for several days, and even Lao Gu, who had always been aloof, had a long-lost smile on his face.
However, neither Ke Yue's paper nor Gu Xinyue and Wang Zihao's paper were the decisive factor.
One of them scored 2 points and the other scored 3 points. Compared with AstraZeneca's paper, they are really not on the table and can only be counted.
"Lu Chen, hasn't your magazine replied yet?"
Wang Zihao asked while the research team was having lunch together.
Lu Chen shook his head helplessly: "Not yet."
"If there is no reply this month, is our experiment..." Ke Yue whispered, her expression was a little bitter. She also devoted a lot of effort to Lu Chen's national nature project.
Hearing this, Lu Chen did not respond, and the atmosphere at the scene was a bit dull.
Everyone understands that if Lu Chen's paper is not accepted within this month, then this national natural project will be declared dead and there will be no way to compete with AstraZeneca.
"It's okay, everyone, please be happy." Seeing that everyone was in a bad mood, Lu Chen could only comfort him, "We are still so young, even if we don't succeed this time, there will be many opportunities in the future!"
Even so, everyone was still a little unwilling. UU read books www.uukanshu. net
Just when Lu Chen was about to continue comforting everyone, suddenly, his phone vibrated slightly.
He originally thought it was a notification sound from WeChat, but when he took out his phone and looked at it, a few big words were displayed on the notification bar: "You have new emails, please check them!"
Lu Chen was startled, new email?
Could it be...
At this time, Wang Zihao came over to take a look and said in surprise: "New email!"
When everyone heard this, they all raised their heads and stared at Lu Chen.
Lu Chen swallowed lightly. He had never been so nervous.
Unlock the phone and click on the message in the notification bar.
The interface jumps to the mail app, and then to the inbox.
Lu Chen's eyes focused on the sender's message, then he paused slightly and looked up at Ke Yue and others, "It's a reply from the magazine."
After hearing Lu Chen's words, everyone sat upright and stared at Lu Chen closely, not daring to express their anger.
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