I Can See Health
Chapter 591 Meeting with AstraZeneca
Remember [new] in one second! Kyoto University First Affiliated Hospital.
Emergency medicine.
In the ward, the sound of monitor alarms and the shouts of doctors and nurses were mixed together.
"Dr. Fan, the patient is sick again!"
The patient on the hospital bed rolled his eyes upwards, began to twitch violently, and foamed from the corners of his mouth.
Fan Jian had already rushed to the bedside and shouted: "One dose of diazepam, intravenous injection!"
The emergency department nurses were highly qualified in rescuing and immediately prepared diazepam injection.
Just when the nurse is about to give the patient medication.
Lu Chen discovered something very strange, "Wait a minute!"
He pointed to the ECG monitor at the patient's bedside.
On the ECG monitor, the ECG is a straight line!
This is so scary.
A straight line on the ECG means that the patient may have stopped electrical activity!
In other words, the patient's heart may have stopped. .
To put it more bluntly, the patient may have died.
Fan Jian looked in the direction Lu Chen pointed.
Sure enough, the ECG is a straight line!
Lu Chen felt a little uneasy and was about to pounce on him before he started CPR.
Fan Jian quickly felt the patient's carotid artery pulse, but he really couldn't find it.
But within a few seconds, a pulse could be felt.
At this time, the nurse shouted again, the heartbeat came back!
Fan Jian broke into a cold sweat on his back, but fortunately it was a false alarm.
Immediately afterwards, the patient's convulsions stopped in less than 10 seconds.
Fan Jian shook his head helplessly: "It's good for an epileptic patient whose cause has not yet been understood. His heartbeat stopped immediately. It's really frustrating!"
But at this moment, Lu Chen was suddenly stunned. He seemed to already know why the patient had epileptic seizures.
Lu Chen stepped forward, quickly checked the patient's pupils on both sides, re-measured the blood pressure, and confirmed that the patient's vital signs were stable.
By this time, the patient had woken up.
"Lu Chen, what's wrong?" Fan Jian stared at Lu Chen in surprise. Did he discover something else?
"Can you retrieve the patient's ECG monitor records?" Lu Chen asked.
"Of course." Fan Jian nodded and turned around to tell the nurse on the side to retrieve the ECG monitor records.
The nurse quickly pulled up the records.
Lu Chen looked through the patient's ECG monitoring record and matched the time. Before the attack, the patient's heart rate was fine, more than 80 times per minute. However, as soon as the convulsion started, the heart stopped beating and there was a long RR interval. Lasted 7 seconds.
"That's the problem!" Lu Chen said in a deep voice.
Fan Jian looked at Lu Chen doubtfully, not quite understanding what Lu Chen meant, "What's wrong?"
"The patient probably had cardiac arrest first and then convulsions." Lu Chen said slowly. "It seems that the convulsions were caused by cardiology disease, not epilepsy as we always thought."
Fan Jian was stunned, "Lu Chen, do you mean this is Asthenia syndrome?"
Lu Chen nodded slightly, "Yes, it's Asthenia syndrome!"
The so-called Aspen syndrome refers to a disease in which the heart suddenly fails to pump blood or does not pump blood at all due to some reason, causing ischemia and hypoxia in the brain, resulting in syncope and convulsions.
If the heart beats too slowly, or does not beat at all, or beats too fast, it may cause insufficient blood pumping and cause syncope and convulsions.
The final diagnosis was only separated from reality by a thin layer of window paper.
Lu Chen pierced the layer of paper, and all the doctors present suddenly realized.
Initially, Fan Jian and the others considered the possibility of cardiac disease, so they also arranged for dynamic electrocardiograms, cardiac color Doppler ultrasound, etc., but no abnormal findings were found.
"Why are there no problems with the cardiac ultrasound and electrocardiogram?" Fan Jiandao said.
Lu Chen smiled, "Because during the examination, the patient did not have convulsions, so naturally there was no cardiac arrest. The electrocardiogram taken at this time will definitely not be able to capture evidence."
Fan Jian nodded, "That makes sense, but why didn't the patient have a cardiac arrest in the first place?"
Lu Chen explained patiently: "The patient only had twitching of one limb at first, but his consciousness was still clear. It is considered that the cerebral ischemia may not have been serious at that time."
"Later, the arrhythmia worsened and the arrest time may be prolonged, leading to confusion and full-blown epileptic seizure. The patient never felt the discomfort of chest tightness, chest pain, palpitations, etc. before the epileptic attack."
The patient just had a sudden convulsion, which occurred directly under the eyes of the bedside doctor and ECG monitor.
So, the real culprit was finally caught!
Just when Lu Chen finished speaking, he noticed a prompt popping up in the system.
"Congratulations, I received a +1 thank you from Fan Jian!"
"Congratulations, the system upgrade completion rate has increased!"
…
"Lu Chen, thank you so much."
Fan Jian patted Lu Chen on the shoulder. Unexpectedly, Lu Chen helped him solve the problem for the second time.
Lu Chen smiled. He also accidentally discovered that the patient's electrocardiogram showed a straight line.
"Do you have a bed? Send this patient to your department?" Fan Jian asked again.
Now that epilepsy has been ruled out, he will not go to the neurology department, but will need to be hospitalized in the cardiology department.
"There happens to be a bed. You can go." Lu Chen nodded, "But Brother Fan, you need to talk to the patient first. He may need to complete the electrophysiological examination and may need a pacemaker. If you don't go for surgery, If so, there may be no need to go.”
"Okay, as long as there is a bed, I will communicate with the patient." Fan Jian grinned. It would be better to transfer such a high-risk patient out as soon as possible.
…
Return to the doctor's office in Heart 1.
Lu Chen told the nurse that he was going to receive a patient from the emergency department.
Although this patient did not have medical insurance, his employer reimbursed him in full!
"Brother, I have a question about the patient just now." Su Rui whispered.
"Ask." Lu Chen smiled. He liked this little junior sister, not because she was beautiful, but because... she could earn thank you points!
Su Rui blinked and asked, "How come this kind of patient doesn't have any symptoms before getting sick? Such as chest tightness, chest pain, palpitations..."
Lu Chen explained with a smile, "Not every patient with arrhythmia will feel uncomfortable. Some people don't have any heart discomfort and fall to the ground directly. Later, it was found that they had sick sinus syndrome. Heart disease The beating is irregular, the brain is ischemic, and it will turn black in a few seconds and then fall down.”
"Wouldn't that be dangerous?"
"Yes." Lu Chen nodded, "So after the specific cause is found out, this patient may need a pacemaker."
Su Rui nodded as she listened. In her eyes, senior brother Lu Chen was so powerful. He knew everything he asked. He was like a treasure chest!
…
Kyoto University First Affiliated Hospital.
General Surgery Ward 1, doctor's office.
Since arriving at Kyoto University, Wang Zihao has felt tremendous pressure!
He never thought that one day he would be able to stand in the top medical school in China.
All around are academic masters and academic gods...
Although he was usually careless and didn't care much about other people's opinions, he was still hit hard in this fiercely competitive environment.
In the entire department, his clinical knowledge and skills may be the worst.
However, a recently published sci paper allowed him to turn the situation around!
As a professional master, it is not easy to be able to complete a sci paper alone.
Even at Kyoto University, where top academics gather, only a small number of people can accomplish this achievement.
After publishing this sci paper, Wang Zihao instantly felt confident!
Usually in the department, he walks straight.
After returning to the dormitory after get off work, Wang Zihao was about to go find Lu Chen, but he didn't expect his sister Wang Ruoxi to call.
"Zihao, are you with Lu Chen now?"
I thought Wang Ruoxi cared about his younger brother, but she opened her mouth to ask about Lu Chen.
"Yes, sister, what's the matter?"
Wang Zihao knew that his sister had paid "special attention" to Lu Chen for some time.
However, after Lu Chen didn't respond, Wang Ruoxi suspended the offensive.
Is the old love rekindled this time?
Could it be that Lu Chen was going to be his brother-in-law again?
Wang Zihao was very confused. Lu Chen was good, but it was so strange to change from brother to brother-in-law!
Just listen to Wang Ruoxi continue: "Recently, Lu Chen published a paper on dapagliflozin, right?"
"Yeah." Wang Zihao responded. He knew that his sister happened to be AstraZeneca's Jinghua regional manager.
Wang Ruoxi said in a deep voice: "Zihao, there is something I need to tell you the truth about."
"Sister, what you said is right. I am your brother and I will definitely not lie to you!" Wang Zihao said in surprise.
Listening to the serious tone of the elder sister, isn't it about emotions?
Wang Ruoxi paused and said slowly: "Then tell me, did Lu Chen complete this paper by himself, or did his tutor help?"
When Wang Zihao heard this, he blurted out: "It must have been done by Lu Chen alone! Professor Li Yao gave some advice at most, and most of the content was completed by Lu Chen himself."
"Really?" Wang Ruoxi still didn't believe it.
This is not a two or three point sci paper!
But one of the top journals in the cardiovascular field!
The department directors of many provincial tertiary hospitals have not reached this level...
"Really! I promise!" Wang Zihao said immediately.
On the other end of the phone, Wang Ruoxi was a little silent. He knew that Lu Chen was unusual, but he still underestimated him.
This time, the superiors actually noticed him.
"Okay, I understand. I'll come to Kyoto to find you tomorrow."
After Wang Ruoxi finished speaking, she hung up the phone.
Listening to the busy signal from the other end of the phone, Wang Zihao curled his lips and said, "To put it nicely, you're looking for me? You're probably looking for Lu Chen..."
…
As for Lu Chen, his mentor Li Yao also contacted him.
"Lu Chen, people from AstraZeneca may be in contact with you recently." Li Yao vaccinated Lu Chen in advance. "They should be talking to you about the Dagli Pure Country Natural Project."
When Lu Chen saw the news, he was a little confused.
"Teacher, why did AstraZeneca come to me?"
"I don't know the details, but they are very interested in your paper." Li Yao replied, "You completed this paper independently, so I asked their people to find you directly."
Although Li Yao has a corresponding author, she is really in Lu Chen's favor.
"Okay, thank you teacher, I understand." Lu Chen was quite confused.
Why did AstraZeneca come to him? Isn't there a competitive relationship between them?
Is AstraZeneca here to "recruit"?
At the same time, Lu Chen also learned from Wang Zihao that Wang Ruoxi would come to Kyoto.
It seems that instructor Li Yao is right, people from AstraZeneca are coming!
…
The next day.
As soon as Lu Chen got off work, he was blocked by Wang Ruoxi downstairs in the dormitory.
"Lu Chen, long time no see."
Wang Ruoxi was wearing a black professional attire, but it still couldn't hide her good figure. She had short shoulder-length hair, and she looked very capable with a hint of charm.
"Sister Ruoxi, why did you come all the way to Kyoto?" Lu Chen greeted her with a smile.
Wang Ruoxi also provided a lot of support for his national natural project on dapagliflozin. For example, experimental drugs are all sold at discounted prices.
This saved Lu Chen a lot of project funds!
"Brother Lu Chen, of course I'm here to find you, and there's something big going on." Wang Ruoxi is not much older than Lu Chen, but has been around the workplace all year round, and her tone makes Lu Chen immature and sophisticated.
"Do you have time? Let's talk somewhere else."
"good."
Lu Chen was also willing to be accompanied by a beautiful woman.
Facing patients every day in the hospital is quite boring sometimes.
They found a cafe near the hospital, found a booth, and started chatting.
Lu Chen couldn't get used to the coffee here. A lot of sugar was added every time.
"Brother Lu Chen, taste it slowly. After all the hard work, the sweetness comes." Wang Ruoxi took a sip of the sugar-free coffee.
"Forget it, I'll just add sugar." In his opinion, life is already very difficult many times, so the external feelings should be as sweet as possible.
"Sister Ruoxi, I heard from my mentor that you are here this time about dapagliflozin?" Lu Chen said straight to the point.
"It's okay, why can't I come to you?" Wang Ruoxi put down her coffee cup and said softly.
Lu Chen secretly glanced at Wang Ruoxi's delicate face, then looked away and coughed lightly, "Of course."
"I won't tease you anymore." Wang Ruoxi withdrew her smile and said seriously: "I heard from Zihao that the 12-point SCI paper you recently published was basically completed by you independently?"
Lu Chen shook his head slightly.
"No?" Wang Ruoxi was stunned.
Lu Chen said slowly: "First of all, this sci paper is not 12 points, but 11.98 points; secondly, I can only say that I completed most of it independently, and I asked Kyoto University professors to help me with the statistical methods."
Lu Chen told the truth, and anyone with a discerning eye could see that most people really don't know how to use this statistical method!
"What did I think?" Wang Ruoxi smiled. She mainly wanted to ask if Lu Chen was acting in name.
Generally speaking, a master's degree program with one or two low-scoring SCI papers is considered excellent.
Once the sci impact factor exceeds 5 points, then you have to consider that this is not a "study valve"!
Nowadays, the second generation of scholars are worse than the second generation of officials and the second generation of rich people.
Even elementary school students start studying genes. Why do many people with master's degrees and PhDs feel embarrassed about this?
"Lu Chen, actually I am here to see you this time on behalf of AstraZeneca China Division." Wang Ruoxi said slowly.
Lu Chen smiled and said, "Sister Ruoxi, just finish it in one breath. What do you want to do with me?"
Wang Ruoxi paused, "I asked you to cooperate."
"Cooperation?" Lu Chen was puzzled, "Isn't AstraZeneca also doing this experiment?"
Thinking of this, he was suddenly startled. Could it be that AstraZeneca wanted to turn their experiment into a "sub-center" of AstraZeneca?
If this is the case, Lu Chen's independent National Natural Science Project will become a subsidiary of AstraZeneca and become a clinical research center in China.
Although there is no need to compete with AstraZeneca, it has also lost the significance of the original experiment, which is no different from choosing to "lay down".
"Lu Chen, don't get me wrong." Wang Ruoxi seemed to understand what Lu Chen was thinking, "The one currently conducting the same experiment as you is not the AstraZeneca headquarters, but a European branch."
"Branch?" Lu Chen frowned, "Is there any problem with this?"
"There are many problems." Wang Ruoxi said with a smile, "If it is a clinical study led by AstraZeneca headquarters, then we won't talk much. There must be a competitive relationship between us. The only one competing with you in scientific research now is a European branch. Department. Our Chinese branch and the European branch are actually in a competitive relationship.”
"Aren't they all the same company? Is it so complicated?" Lu Chen asked doubtfully.
Wang Ruoxi shook her head, "AstraZeneca is a multinational giant. The bigger the company, the more complicated the relationships. People in the branches all want to be promoted to the headquarters. Therefore, there are many conflicts between each branch. There is a certain degree of competition, which mainly depends on which district’s performance has improved more, or who produces more influential scientific research.”
Hearing this, Lu Chen somewhat understood.
"Oh, so you want to cooperate with me on the dapagliflozin project and compete with me in the European division?"
Wang Ruoxi smiled and nodded: "That's right! The headquarters supports this kind of scientific research competition, UU Reading www.uukanshu.net because no matter which side wins, it will be the AstraZeneca headquarters that ultimately profits!"
Lu Chen pouted, these Europeans and Americans have a good plan!
No matter which division wins, it will ultimately benefit AstraZeneca headquarters, so the headquarters acquiesces to this competition.
"Actually, we didn't originally want to compete with the European branch on this project. The progress in Europe is very fast and we can't keep up." Wang Ruoxi added, "But because of your sudden rise, our Chinese branch noticed you. Only then did I have the desire to compete with the European division again.”
Lu Chen frowned when he heard this.
At present, it seems that if nothing unexpected happens, the experimental progress of AstraZeneca's European branch will definitely be faster than theirs!
From this point of view, the Chinese branch's request for cooperation is an opportunity.
But AstraZeneca is a foreign company after all. Blood-sucking capitalists cannot see clear benefits, so they will definitely not take action easily.
"How do you want to cooperate?" Lu Chen raised his head and looked at Wang Ruoxi.
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