I Have a Research Support System

The school bus driver swished away in the bus, leaving only three figures under the street lights.

"Oh, my God, look what I found?" Chen Wanqing's gaze swept Xu Qiu and Han Jiaying back and forth.

Xu Qiu scratched his head and tried to explain, "I said I was passing by, senior sister, do you believe me?"

Chen Wan gave him an innocent look, made an expression of "do you seem to think I'm stupid", and said, "I've already seen that you two have problems, and I asked you yesterday, but you still lied to me, hehe. "

Seeing that the explanation was fruitless, Xu Qiu graciously pulled Han Jiaying to her side, the junior girl blushed and did not resist.

This act is a bit like an oath of sovereignty, but the other party is a senior, so I always feel that there is something weird about it.

According to his thinking, the relationship between the two will be announced sooner or later anyway, since it was discovered, there is nothing to tweak.

It's just that they were together on the first day, were suspected on the second day, and then the relationship was exposed on the third day, everything was so bald.

Chen Wanqing didn't delve into what Xu Qiu lied to her yesterday, her gossip soul was burning, "Tell me, when will it be good."

"This Monday." Xu Qiu answered truthfully.

"Just the day before yesterday, uh..." Chen Wanqing thought for a while, then suddenly said:

"I understand. The three of us acted together before. Yesterday was the first time you two acted alone, but Tian Qing broke through you. If I had known this, I should have walked back to Handan earlier."

Xu Qiu didn't answer, and Han Jiaying interjected weakly, "Well, senior sister, can you keep it a secret for us, I don't want to spread the word."

"No problem," Chen Wanqing vowed, "I will keep it a secret for you."

"Yeah, let's go back then."

"Ok, bye."

Waving goodbye to Xu Qiu and Han Jiaying, Chen Wanqing looked at the backs of the two leaving hand in hand, standing there, as if thinking of something, her cheeks flushed slightly.

After a long time, she whispered to herself, "I'm about to graduate in a year or so. I won't stay in school no matter whether it's after my PhD or looking for a job. After all, she and he are more suitable."

Xu Qiu and Han Jiaying started to communicate after walking a long distance.

"Today I was so busy debugging the TRPL instrument that I forgot that you came back together." Xu Qiu said angrily.

"It's okay," Han Jiaying said softly, then tilted her head, "Well... You said that senior sister wouldn't betray us, right?"

"Looking at her appearance, she probably won't." Xu Qiu was also a little uncertain.

Chatting all the way back to the southern campus, the two walked to a dark corner with no one around, and then stopped at the same time.

The smell of hormones is in the air...

...

Back in the dormitory, Xu Qiu thought about it, and decided to go to Zhangjiang to do synthesis tomorrow. The system at hand was developed by himself, or he had to be responsible for completing it.

Based on the further optimization of the two structures of PDI3-B-5/6, the optimization path has been reported to Mr. Wei once before. There are several methods such as fused rings, bay-position modification, N-position side chain engineering, and introduction of heteroatoms.

Although the structures of the two molecules are slightly different, they can be regarded as the same system on the whole, so he intends to use each of them to make an improvement.

The best result is that both improvements are positive, that is, both can improve the photoelectric performance of the material, then the next step is to integrate the two improvements into the same molecular structure, and there is a high probability that a higher level of performance improvement can be obtained.

However, there is a more embarrassing problem, that is, there are some shortages of raw materials. The yield of the two 3D-PDI molecules obtained before is less than 100 mg, and 15 mg is left in the Handan campus.

The remaining dozens of milligrams of materials are directly put into the reaction, and the estimated product yield is only 40 mg, at most 50 mg, which cannot support further optimization, and can only be re-synthesized from scratch.

Early the next morning.

Xu Qiu and Han Jiaying made an appointment for morning exercise, and after they had breakfast, they left for Zhangjiang by one bus ahead of time, mainly to avoid Chen Wanqing and allow them to spend more time together.

On the school bus, the two chatted for a while. Xu Qiu remembered that they hadn't exchanged anything related to the experiment in the past few days, so he asked, "How is the synthesis doing recently?"

"Well... it's okay. The synthesis of PDI-8 and the bromine substitution reaction of several PDI molecules are going well. I'm mainly busy with this these days, but..." Han Jiaying changed the subject:

"The second step reaction of the 3D-PDI molecule I did, that is, the reaction of connecting boronate on the thiophene ring, had products, but the yield was extremely low, less than 20%. I'm not sure if it was me The product I need, I plan to try again next week."

Afterwards, she smiled sweetly, "Anyway, your system has achieved preliminary results, so you can give priority to your system this week."

"Okay," Xu Qiu nodded, and then fell into thought, "The reaction yield is low, let me think about whether there is any solution." During this time, he was also writing a literature review, reading a lot of literature, and doing a lot of experiments. The details are still in my mind.

After a while, Xu Qiu sorted out his thoughts, and said slowly: "In the general direction, methods such as prolonging the reaction time, increasing the reaction temperature, or changing the reaction solvent and catalyst, and making the amount of a certain component excessively large, etc., can be used. These, there is another path..."

"What path?" Han Jiaying asked curiously.

"Using the microwave reaction method," Xu Qiu explained: "We originally planned to use it when we were making polymers, but at that time there were not many synthesis times, and the priority was not high, so it was abandoned later, but it is different now. , Small molecule synthesis requires many steps, if there is a microwave reactor, it will definitely bring a lot of convenience."

"Oh, the microwave reactor," Han Jiaying thoughtfully, "I see that there are many research groups using it in the literature, which can greatly shorten the reaction time, but the price does not seem to be very cheap."

Xu Qiu hummed, "Imported ones are about a hundred thousand. I don't know if the domestic ones cost tens of thousands. However, we can also make one ourselves."

"Make one yourself?" Han Jiaying tilted her head and thought for a while, "You mean Microwave..."

"That's right, you can modify it with a microwave oven. After all, the principle of a microwave reactor is basically the same as that of a microwave oven, but the safety and effectiveness cannot be guaranteed. Forget it..." Xu Qiu shook his head and said:

"Let me find time to mention something to Teacher Wei. The group just bought a TRPL, and I don't know if the funds are enough. I feel that Teacher Wei has spent a lot of money on me since I joined the group."

"Anyway, the money is spent wherever it is spent, and if it is used to produce results for the senior brother, Teacher Wei must be happy before it's too late." Han Jiaying chuckled.

...

Zhangjiang Microelectronics Building.

Xu Qiu opened the door of the office with the key, but sure enough, the senior sister hadn't come yet.

As usual, start the preparatory work before the experiment, calculate the feeding ratio, and write it down on a sticky note.

It's just that the two are in the same room, no one disturbs them, and they are blessed with a DEBUFF that reduces work efficiency by 30-100%.

half an hour later.

Chen Wanqing walked to the door of A501, and subconsciously prepared to take out the key to open the door, but found that the lights inside were on and voices could still be heard.

She listened carefully, and suddenly looked strange.

Then he knocked on the door three times, and there was the sound of tables and stools rubbing against the floor, and it quieted down after a few seconds.

Then she turned the doorknob, pushed the door open and entered.

"Morning sister~"

"Morning, senior."

Looking at the couple holding hands at the desk, Chen Wanqing sighed softly, "Hey, it's early in the morning, you guys are going to kill me."

He casually threw his schoolbag on the sofa, took out his laptop, and said, "By the way, Xu Qiu, you came just in time. Let's discuss the optimization path after the C1 system."

"Okay." Xu Qiu naturally didn't refuse, this was what he promised his senior sister before, even if she didn't mention it, he would find an opportunity to propose it.

Chen Wanqing started the computer, opened the PPT file of "synthetic route" on the desktop with the touchpad, and said: "I designed three molecules, C2, C3, and C4 based on C1, corresponding to different molecular structure optimization directions. Among them:

C2 is the optimization of the side chain on the D unit, such as replacing the side chain of the benzene ring with a thiophene side chain, such as changing the number and position of the side chain, which can be further split into molecules such as C2-1 and C2-2;

C3 is the regulation of the conjugate scale of the main chain of the D unit, including increasing and reducing the number of conjugated fused rings, and can also be further split;

C4 is an improvement based on the A unit. The commonly used A unit in traditional A-D-A molecules is 'rhodanine' and its derivatives, which are five-membered heterocyclic rings containing nitrogen and sulfur atoms, and have carbon-oxygen double bonds and carbon-sulfur double bonds. For this type of electron-withdrawing group, my idea is to design a new A unit based on a six-membered ring, which is why I have so many steps in the synthesis reaction. "

After the introduction, Chen Wanqing tilted her head: "Student, what's your opinion?"

Xu Qiu found that the senior sister's synthetic route is now much more complete than when she first discussed it after taking leave. Obviously, as time goes by, she has been perfecting her own thinking, and she is not standing still.

After thinking about it for a while, many ideas came to Xu Qiu's mind. After deliberating for a while, he opened his mouth slowly:

"C2 and C3 paths are currently being researched by many people, and there are a large number of ready-made structures that can be used. Since the senior sister is rushing to make a big article, it is better to focus on the C4 path. There is no need to take care of everything.

Based on the C4 path, I don't think it is necessary to entangle the five-membered ring or the six-membered ring. OK.

For unit A, the focus is still on the electron-withdrawing group, and you can try to introduce strong electron-withdrawing groups such as cyano, nitro, and fluorine atoms.

However, relatively speaking, the priority of the nitro group is relatively low. This group seems to be incompatible with organic photovoltaic materials. At least I have not seen any donor or acceptor with a nitro group in its molecular structure.

As for the cyano group and the fluorine atom, from the perspective of the difficulty and danger of the experiment, the cyano group has a higher priority. "

"Cyano?" Chen Wanqing muttered thoughtfully, "It sounds so dangerous..."