Rebirth of the God-level Xueba

In 1985, Yang Rui was quite confident in his gender identification technology.

The gender identification of embryos was originally the highest threshold for embryo transfer.

Not to mention the time when PCR was invented not long ago.

PCR can be said to be the strongest general-purpose technology that has been born in the field of biotechnology in recent years, and its impact on biology is no less than that of the Watt steam engine on the industrial world.

Moreover, the impact of pcr is faster and stronger.

If it is an exaggeration to say that every mechanical factory during the industrial revolution had one or even multiple watt steam engines, it is not an exaggeration at all to say that every modern biological laboratory has one or more PCR instruments.

Of course, any technology has a development process, and the more general the technology, the more so.

In 1983, when pcr was just born, scholars were still at a loss, but by now in 1985, many applications have been developed.

Using pcr for embryo identification is a technology that has just been developed for a year.

Prior to this, embryo identification was still using cytogenetic analysis, which was very complicated and the accuracy rate was not high, at least it could not be compared with the pcr technology with a stable 95% accuracy rate.

As far as the domestic situation is concerned, the correct rate of many laboratories using cytogenetic analysis methods for gender identification is only 80%.

It sounds good. If 80 points are put on the test paper, it seems to be an excellent result.

However, an 80% correct rate is basically a disaster in practical applications, and it is almost difficult to use.

Suppose a farmer needs 100 heifers and ends up with 80 heifers and 20 heifers. That's a problem that goodness can't solve—it can be solved Only the legendary veal is left.

Restaurants, of course, love cheap veal, but farmers don't.

This is true for 100 cows, but what about 1 million cows?

Thinking about the needs of China Animal Husbandry, we can understand the seriousness of this problem.

For China Animal Husbandry, the only thing they need are cows, because their goal is to expand the population. As for young bulls, the domestic market prospects are not very good.

The most important thing is that they use US dollars for breeding, while sporadic meat sales can only get RMB.

In other words, an 80% correct rate is an additional 20% foreign exchange expense for China Animal Husbandry. This is of course an intolerable expense.

For large ranchers, among the 1 million bulls ready to sell meat, 200,000 cows suddenly appeared, eating a lot, not growing fat, and the meat was not good enough to be sold as calves. In the end, it might as well just grow naturally without sexing and control programs, and then sell the heifers.

Therefore, accuracy and accuracy are the key points of gender identification and gender control.

In the pre-PCR era, animal husbandry was not very successful in gender identification and gender control. Most farmers and agricultural institutions would not adopt this costly and ineffective solution.

In the post-PCR era, the extremely high accuracy and correct rate will bring about revolutionary changes.

However, Yang Rui's thesis does not intend to consider this revolutionary change.

His thesis focuses more on the application of pcr.

As the inventor of pcr, expanding the scope of pcr technology was originally a gimmick that journals like—academic journals also need gimmicks. Experiments done with cells are more interesting.

After all, academic journals are a kind of journals, and they also need attention and recognition from scholars.

Of course, this alone is not enough to be listed on "Nature".

After all, it is the world's leading and famous journal, and the gimmick is just the icing on the cake.

Yang Rui's real confidence lies in the primers he designed.

Primers are the prerequisite for PCR. If PCR is described as a computer, primers are the applications of this computer. To do different experiments, it is necessary to design different applications. Primers in the 21st century already have a common design template, and their work is relatively simple, which can be compared to a computer operating system. However, in 1985, the newly born PCR technology was more like a complex mainframe, with no operating system Systems are available, and there is no easy input and output method, requiring additional design and specialized applications for each study.

At this time, the primer designed by Yang Rui is actually an excellent template.

Yang Rui believes that there will be many scholars who are willing to take a look at the PCR primers he personally made.

Although it is far from being perfect, there is nothing perfect about academics.

On the other hand, Yang Rui sent his thesis to Darbecco and other scholars at the same time, not only for further communication with them, but also for the purpose of playing side drums.

The exchange of work through letters is something that Western scholars have been familiar with hundreds of years ago. Some of Gauss's research is still collected from his letters.

Before the popularization of e-mail, scholars from various countries basically maintained this communication method.

Anyway, for academic research, a delay of a few days or more than ten days is nothing.

Dalbecco and others are also happy to learn about Yang Rui's work. As far as the current development of biology is concerned, there are only a few top figures, and Yang Rui can barely be among them. Naturally, everyone wants to know him.

In general, it is not as easy for Yang Rui to publish a paper in "Nature" as in domestic journals, but it is not too difficult.

Even if Yang Rui doesn't know his own influence well, this paper can be regarded as an attempt.

Yang Rui waited quietly, and continued to direct the genetic engineering laboratory to carry out systematic experiments—the first batch of 10 Simmental cattle were brought into the backyard of the genetic engineering laboratory.

The temporary cow pens are a bit crude, but the Simmentals probably don't care.

Several experimenters looked at these cattle curiously. For those who are used to scalping cattle, the robust Simmental cattle are indeed much taller and stronger. In terms of size, it is a bit like the gap between the Chinese Pastoral Dog and Erha.

Sun Zhengchu and Wang Ziang quickly checked the 10 cows and recorded the data.

Both of them are traditional geneticists who have been solving physiological problems for animals all year round.

The ten new cows became the responsibility of Sun Zhengchu and Wang Ziang.

Yang Rui basically doesn't need to manage anymore. He doesn't know how to raise cattle, and he doesn't know how to take care of the happy life of cattle. In fact, he doesn't need to do these things.

Now, all the points have been breached, all that is needed is to do it again in the previous order.