Rebirth of the God-level Xueba

"Sister-in-law, what happened?"

"Sister-in-law, are you okay!"

"Sister-in-law, what's the matter?"

In the room, all kinds of inquiries and noises turned the academic discussion place into a beer stand in an instant.

Yang Rui suddenly seemed to hear the sound of rolling up his sleeves.

There were also impulsive young middle-aged people rushing into the kitchen and staring at him.

Yang Rui thought: What do you guys think I would do in a house with dozens of people?

"It's okay, something got into the eye." Dr. Li's voice was a little soft, with a forced smile on his face.

Professor Cai is most familiar with his wife, turned his head to look, and shouted: "Yang Rui, what's going on?"

Yang Rui walked out of the kitchen helplessly: "I really don't know."

"It's none of Yang Rui's business." Doctor Li was a little embarrassed, rubbing his hands on the apron again and again, and said, "I heard Yang Rui talk about thalassemia patients, and I was a little emotional."

Everyone is clear about the history of deferiprone. When he said this, the atmosphere that was still a little heated at first became depressed in an instant.

After a long time, Professor Cai said: "Yang Rui has done a good thing, everyone should be happier."

"You have been doing such a good thing for so many years." Dr. Li was embarrassed to say that if it was someone else, but facing his husband, Dr. Li couldn't help his emotions fluctuating, and said: "There are many patients in the hospital, all of whom the doctor wants Help, can’t help. Let’s talk about thalassemia, the doctors in our hospital have donated money several times, and there is nothing they can do.”

"Isn't science developing? Two years ago, everyone didn't know that deferiprone can be used as an iron chelator. Tell me, do you think so?" Professor Cai comforted his wife in embarrassment.

Dr. Li was a few years younger than Professor Cai, curled his lips and said, "I think you, a member of the academic department, have not made as much contribution as Yang Rui."

"You're right, so everyone is optimistic about Yang Rui." Professor Cai naturally nodded vigorously.

The frail Shen Xingde added with a smile: "Yang Rui is the sun at seven or eight o'clock and has a bright future. The future of our Chinese biological world depends on young people like Yang Rui."

Dr. Li's mood fluctuated at this time, and he said to Shen Xingde who was familiar with him, "It's true that Yang Rui is the sun at seven or eight o'clock, but if you ask me, an old doctor, Yang Rui, the sun at seven or eight o'clock, is better than you guys." The sun is bright at noon."

"Sister-in-law, we are the sun at seven or eight o'clock in the evening. It can't be too bright. If it's too bright, the leader can't sleep." Wu Hongbo was silent, bringing the atmosphere back a bit.

Yang Rui also hurriedly said: "Don't dare to say that, I'm still in the process of learning, but I was lucky enough to make the active substance of deferiprone. At that time in the laboratory, I also felt a little helpless. Let's do it again. I can’t say if I can do it again.”

"Yang Rui is too modest. I read your desferiprone experimental briefing. If you are lucky, our Chinese Academy of Sciences can be abolished."

"Old Wu, don't talk nonsense, you are bragging on behalf of the Chinese Academy of Sciences today, and someone will come to Peking University to kick the hall tomorrow." Professor Cai helped Yang Rui hold an umbrella in advance.

Yang Rui also hurriedly said: "It's really lucky, and it's also because I happen to know some relevant knowledge."

What Yang Rui said is also true. In the synthesis of a compound in the laboratory, 30% depends on equipment, and 30% depends on techniques.

Forty percent depends on luck. Looking at the graduate thesis of the Chinese Academy of Sciences every year, it is also a doctoral student of the Chinese Academy of Sciences. Some students can synthesize super-complex compounds in about one year, and some students cannot graduate after four or five years, and some even delay their graduation until six or seven years. . If you say that the level of graduates who graduated later must be lower than those who graduated earlier, that is not always the case. Sometimes it is luck, which can also be judged by the achievements after graduation.

Of course, Yang Rui's laboratory level has indeed improved. If it was the era of graduate school, Yang Rui would not think about such a synthetic experiment at all, and would not even do it by copying it. It is too complicated, there are too many variables, the cost is too high, and the difficulty is too high. It can be said that it is full of Reason not to do it. The tutor will not assign such a task to the master's students in a brainstorming manner.

However, during his more than a year at Peking University, especially in the ion channel laboratory, Yang Rui's experimental level has increased several times.

Experience is such a thing. In the era of graduate school, the annual funding for Yang Rui from the tutor is tens of thousands of RMB, which is still tens of thousands of RMB after the era of inflation. Yang Rui diligently does a year of experiments, and then examines his work, and spend most of the time doing repetitive simple experiments to save money.

It will be different after having an ion channel laboratory. Yang Rui spent millions if not ten million this year. Although it cannot be said that flowers watered with money must be more beautiful, but more flowers watered It is also natural to improve the watering technique.

The beautiful gardens of rich people are not some unorthodox and unthinkable event.

Even by the standards of later generations, Yang Rui’s work in this year is more than the experience of ordinary postgraduates in the three years of postgraduates and three years of doctoral work. Experiment a lot, think about so many variables independently.

To put it further, an ordinary researcher starts to understand what scientific research is all about as a graduate student, gets started as a Ph. How much money do you have in your life to spend when you retire? Judging by the standards of the 21st century, one million is a must, ten million is rare, and thirty million is basically impossible.

However, Yang Rui's research on ion channels to PCR research, from the technical improvement of coenzyme Q10 to the synthesis of deferiprone, may not be able to spend the 30 million funds. questionable.

Read 300 Tang poems by heart, even if you don't know how to compose poems, you can also recite them.

Any great innovation starts with imitation.

It should be said that in terms of deferiprone research, Yang Rui is still not innovative, let alone great, but for him personally, this is a great leap forward.

If any kind of drug is placed in front of Yang Rui, Yang Rui dare not say that he can develop a brand new variety, but he dares to make a brand new generic drug.

This level, even if we go back to the 21st century, is enough for Yang Rui to find a job with an annual salary of hundreds of thousands in the industry. It is possible to get a first-class salary in the industry for an interview in a pharmaceutical company. Being the chief engineer of a generic drug factory of a state-owned enterprise is almost enough.

In 1984, Yang Rui's level naturally rose even higher.

Professor Cai and others also know this point. They don’t need to look at any illusory inspiration, and they don’t even need to add the meaning or value of deferiprone. They just independently synthesize dozens of compounds and conduct animal experiments on many compounds. This has already been done in China. It's top-notch.

Instead of removing iron excrement and removing iron urine, this kind of research can also show Yang Rui's ability.

And it is more powerful than dry data.

In the midst of everyone's admiration, Dean Liu said regretfully again: "It's a pity that deferiprone was made by Huarui Laboratory. If we made it at Peking University, it would also fill the gap in China."

"Sinovel's lab can be counted, the main work is done in China." Wu Hongbo said a serious word.

Yang Rui replied: "All the work is done in China."

"Are foreigners involved?"

"I borrowed a researcher from a pharmaceutical factory from Zeneca to understand the situation. He did not participate in the research. During the animal experiment, a professor from Cambridge, England participated, but she did not participate in the synthesis process at all." Yang Rui paused and said: " The main work of the animal experiments was done by Professor Grace and Chinese researcher Wang Xiaoyun. Wang Xiaoyun used to work in our @Beijing Institute of Biological Products, and the contribution of the two is about ****."

Yang Rui spoke very seriously, regardless of whether it was a private occasion, everything he said now was useful. In particular, the issue of scientific research contributions should not be talked about at home or abroad. Magazines such as "Nature" and "Science" even have special mechanisms that require scientific research participants and organizers to describe their contributions in detail. . In the selection of various awards, contribution is also a key factor for the selection party. The same research may involve three people, maybe thirty people, and may involve the long-term development of the past sixty years, but the Nobel Prize can Give it to three people, who will be counted at that time, that is, the contribution has the final say.

Several people nodded to express their understanding, and said, "Animal experiments cannot be regarded as the focus of deferiprone research."

"Have you adjusted the compound after the animal experiments?" Wu Hongbo asked more carefully.

Yang Rui shook his head and said, "No, the animal experiments were done in one go, and the results were very good."

"Then I think it's okay. I suggest that we entrust the sun at seven or eight o'clock in the morning. If the awards are judged recently..."

"The awards are inappropriate, and small awards are meaningless. If it is a big award, Yang Rui is still young." Professor Cai is well versed in the unspoken rules of the domestic scientific research circle, and such things as ranking seniority are indispensable at all times. As a student of Yang Rui and in his early 20s, if he wins a grand prize and squeezes out countless seniors in their 50s, 60s, or even 60s and 70s, what will happen?

If it is a fringe scholar who is hungry, the cake is brought to his mouth, no matter whether it is poisonous or not, he will naturally take a bite, but Yang Rui has a paper from "CELL" on his chest, and a super-level quotation from "Nature" on his back. , I have already eaten a full stomach, so naturally it is not worth fighting for a piece of meat.

Professor Cai glanced at Yang Rui, and simply said: "Yang Rui, what do you think, why don't you bring it up?"

Everyone looked at Yang Rui.

Yang Rui instantly realized that Professor Cai had given him an excellent opportunity.

This is an extremely rare opportunity. Among the scholars present, there are only two academic committee members. An Linhai and Shen Xingde are also at the level of quasi-academic committee members. They have high reputations in the industry. Moreover, they come from different units. The chairman of the project application committee, Shen Xingde is the mainstay of Tsinghua's biology, Wu Hongbo and Qing Zhiyong are the big mountains of the Chinese Academy of Sciences in biology.

Although so many members are members of the circle invited by Professor Cai, the decisions they are making now are much greater than the energy that Professor Cai can erupt by advocating alone.

Yang Rui's little heart was beating fast again.

"I would like to invite the country, our country's scientific research community, to recognize my contribution in PCR technology." Yang Rui said the most important achievement to him so far.

Shen Xingde asked: "Didn't the PCR test result?"

"Yes, but I hope to explain the facts we have identified in an American court in a more authoritative way." Yang Rui said: "Sinovel is currently in a lawsuit against DuPont in the United States, and American courts value the facts in court. The fact is that all evidence must go through the courts, and it would be most useful if domestic authorities could send representatives to the United States to prove my contribution to PCR technology in court.”

If he hadn't done the result appraisal at the beginning, what Yang Rui is making now is an unreasonable request.

However, if the result appraisal has been done, it becomes easier just to explain this fact.

Professor Cai's eyes followed Yang Rui's and turned around on everyone's faces, focusing on Wu Hongbo. The latter is also a member of the academic department, which is equivalent to an academician in the United States, and his status is the most appropriate. Moreover, he has no teacher-student relationship with Yang Rui, so it is more convincing.

Wu Hongbo was a little hesitant. Whether he represented the Chinese Academy of Sciences or something, it was not a trivial matter, at least he had to issue documents.

Yang Rui said: "It won't take too much time. The court arranges the time, and we will go there. It can be completed in three days at least, or a week at most. The court can testify in half a day at most."

Wu Hongbo's eyes lit up: "Hey, testifying for half a day, don't you have seven days to travel?"

Yang Rui said with a smile: "It doesn't matter if you want to go out to play, but there is no subsidy for public travel."

"Is Hua Rui in charge of food?"

"That's for sure."

"Okay, then I'll go." Wu Hongbo slapped his thigh and said, "Who else is going? Yang Rui, how many people do you want?"

"The more the better." Yang Rui smiled. These are scientists who are also internationally recognized. For Yang Rui, they are now helping Yang Rui to testify, which will not only help PCR gain recognition in court, but also help Yang Rui and PCR gain recognition in China.

In the future, the Nobel Prize will be judged. These are very important historical recognitions!

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