Rebirth of the God-level Xueba

For the Chinese government, which is undergoing drastic reforms, it is too easy to establish or abolish a department. Many ministries and commissions have been abolished, established, reorganized, and restructured. A mere food and drug administration is really nothing.

However, without Yang Rui's interference, the state's upper-level institutions may not necessarily notice such trivial matters.

China in the 1980s, it is no exaggeration to say that a thousand wastes are waiting to be rebuilt. There are too many major events that affect future generations. It is really not a big deal to establish a food and drug administration ten years earlier or ten years later.

However, as a former ordinary person and a foodie, Yang Rui's resentment towards food and drug supervision has long been deep.

Whether it is gutter oil or Sudan red, whether it is poisonous capsules or high-priced drugs, it can be described as hard to come back.

The establishment of the Food and Drug Administration 10 years later and 10 years earlier may have completely different outcomes.

Moreover, this is a very cheap thing.

It is not that China does not have food and drug management agencies. The Department of Pharmaceutical Affairs under the Ministry of Health is the standard drug management agency. Such institutions perform part of the drug management functions, coupled with the management of imported drugs by the National Medicine Foreign Trade, China's food and drug management institutions are not too few, but too many.

Merging and reorganizing these departments is more of an administrative job, as long as you are willing to do it, you can do it.

Of course, it is impossible to achieve truly pure food and medicines, but from Yang Rui's point of view, the drug management system of later generations was actually very good at one time. Ordinary people's sense of well-being can be greatly improved with a slight improvement.

At the very least, when Yang Rui can influence the upper-level politics, he is more willing to make such an influence.

After the "People's Daily" published the article, within a few days, there were more public opinions discussing food and medicine.

That's what the so-called hair dryer is.

Yang Rui's life also became a little bit more busy. Apart from working in the laboratory, he had to go to Fuyou Street every other day to act as a consultant.

Minister Chen would also come here from time to time, and more often, Director Wang would act as the mouthpiece and contact person.

Although at the local level, cadres at the bureau level are already great officials,

But in the central government, Director Wang has to be a man with his tail between his legs. Even if he wants a small hall for conversation, he has to politely ask the staff at the departmental level: "Can I borrow a place for an hour?"

The staff was also very polite, but they looked at the notebook in a business-like manner, and said, "I don't have an hour to spare, can 40 minutes be enough? You have to come out when the time comes."

Director Wang nodded and said "Okay", thanked him again, wrote his name on the registration form, and then turned around with a wry smile and said, "No way, everyone is short of time, so we can only hold a small meeting here."

As he spoke, he quickly led a few people to the small room that was temporarily borrowed, spread out the documents, and said, "The things were sent to everyone yesterday, you should have read them all."

Several people nodded.

"Okay, then let's go directly to the discussion to save time. In addition, Secretary Hong from the hospital office will come to listen to our discussion later, so don't be nervous, just proceed as usual." Director Wang explained the situation as usual, and then Opening the file, he said: "Let's discuss the issue of food and drug supervision and management now. Regarding system reform, comrades from the Economic Reform Commission are working on it. Our group discussion today will only discuss scientific issues, that is, how to carry out substantive issues." management, how inspections and supervision are carried out.”

While listening to him, Yang Rui took the opportunity to look to both sides. The scholars who came basically knew each other.

There are two academicians, one is Academician Wu Hongbo who is very familiar with him. Like Professor Cai, Academician Wu Hongbo is one of the scholars who support him the most, and the relationship between the two is relatively close in private.

Another old academician from the Chinese Academy of Sciences is also an acquaintance, Xue Jianjian, who used to be the GMP preparatory committee.

In addition, Professor An Linhai of Peking University is an associate academician who was nominated twice, and he is now the chairman of the project application committee of the Ministry of Health. Seeing that the next academician is firmly in his arms, he also came to this office.

As far as the status of domestic academic circles is concerned, academicians and associate academicians still surpass Yang Rui by a little bit. However, both academicians are veteran academicians and do not know much about medical research. Researcher Wu Hongbo works in the Institute of Genetics, and he is not very Good at this.

In comparison, Professor An Linhai has a higher degree of professional fit.

Of course, there is a limit to being tall, and in terms of purely academic ability, few people present dare not compete with Yang Rui.

Articles are the footsteps of scholars. Yang Rui has now posted all of them on CNS, and his academic works are used as textbooks in European and American universities. Whether it is looking at the content or the results, Yang Rui's academic achievements are obvious to all.

Therefore, everyone, including several other young and middle-aged professors, first set their sights on Yang Rui.

"Well, Yang Rui, you should talk first." Although Director Wang didn't like Yang Rui's overreaching in some aspects, he also liked Yang Rui's cheerfulness and efficiency in the meeting.

Relying on his young age, Yang Rui could easily be forgiven even if he was outspoken. When he mentioned the Food and Drug Administration that he was quite interested in, he said without hesitation: "Let me talk about medicines first. I think , the new agency should accomplish two goals."

Director Wang was very familiar with Yang Rui's goal theory, so he nodded naturally.

"First, medicines should be safe, and we must learn from the lessons of Ribodin."

"this is necessary."

"Second, the drug should be effective."

"Of course medicines are effective. If they don't work, they're nothing medicines." Director Wang smiled.

Yang Rui shook his head slightly, and said: "The effectiveness of drugs is a very arbitrary standard. As far as the US FDA is concerned, their method of proving effectiveness is a surrogate endpoint."

"Alternative end point, I seem to have heard the term before."

Yang Rui took advantage of the situation and explained: "The surrogate endpoint is a relatively objective evaluation standard, but there are also problems. For example, whether an anticancer drug is effective, the criterion for judging the surrogate endpoint is whether the malignant tumor has shrunk."

"However, just because the tumor has shrunk, it doesn't mean that the medicine will be effective." Director Wang still has a certain understanding of the cancer that everyone fears.

Yang Rui nodded and said: "You are right. The shrinking of the malignant tumor does not mean that the cancer has been relieved. Therefore, it is only an expedient measure to prove the effectiveness of the drug by replacing the end point."

"Do you have a better strategy?" Director Wang's eyes widened curiously.

Several other people also looked at Yang Rui.

Yang Rui shrugged and said bluntly, "No."

Several people were gasping for breath.

Didn't you say anything.

Yang Rui said: "I just want to explain that what we actually need to do is a systematic work, and many standards need to be formulated, and sometimes the standards are not satisfactory. In this regard, I think experts A committee, or something like an advisory board, is essential."

"Of course, we have already considered this aspect." Director Wang was not surprised by this, and said on the spot: "Everyone present is our priority."

At this time, Secretary Hong came in, nodded to the people around him, and sat down upright, as if listening in.

Director Wang greeted and said, "What about the food?"

"I think the focus of monitoring is on additives, because additives need to be produced by factories and are better controlled." Yang Rui said, and then said: "I am in favor of using additives in an appropriate amount, but I think manufacturers should be encouraged to use additives as little as possible. .”

"This will affect the sales of additives."

"But it will make the added value of food manufacturers higher, because they save a lot of money on additives and can improve their competitiveness in an all-round way. For example..." Yang Rui thought for a while and said: "Heinz in the United States is a very good company. For example, they were originally a company that produced ketchup. In the United States at that time, a large number of preservatives were added to ketchup, but Hunts of the Heinz Company discovered that if very fresh fruits were used in the production of ketchup, and disinfection measures were adopted, there would be no problem. With safe bottling technology, there is no need to use preservatives at all, just like our northerners make homemade tomato sauce in winter, it does not need additives, but tastes better.”

After a pause, Yang Rui said: "Better taste means more sales and higher prices. However, the use of fresh fruits, better disinfection measures and safe bottling technology also means a lot of upfront work. Investment, if the national policy does not support, such a factory cannot continue to operate, not in China, nor in the United States."

"However, if the factory persists and the products are recognized by the market, this means a steady stream of income. We should support and support, and it should be such a company." Yang Rui said very smoothly, and let several people Listen up.

However, only 40 minutes of discussion time cannot be given to Yang Rui.

Director Wang quickly took notes and named academician Wu Hongbo.

Academician Wu Hongbo is also eloquent.

Several people spoke in sequence, and the 40 minutes were quickly consumed.

Director Wang hurriedly packed his things to make room for the people who came after him.

At this time, Secretary Hong came to Yang Rui and said, "Committee Yang, can you spare some time recently?"

"Of course." Yang Rui looked at him questioningly.

"Mr. Qiao is very interested in the current biological and medical information. I would like to ask you to give it to him and some colleagues in the courtyard. Do you think it will work?" Secretary Hong smiled slightly.

"Lesson for the leader?" Yang Rui was very surprised.

Secretary Hong nodded lightly, and said, "It's mainly the leaders of the State Council. It's better to keep the content simple."

"That is to say, I want to teach several leaders of the State Council?" Yang Rui asked repeatedly with wide-eyed eyes.

Secretary Hong nodded, smiled slightly, and said, "The exact time is undecided, but you can start preparing lessons now."