Rebirth of the God-level Xueba

A chat at a dinner party did not prompt Yang Rui to make a decision.

The cloning of Dolly the sheep is an achievement of genetic engineering. Although genetic engineering belongs to biology and is a large category in biology, for biological researchers, the span of these two areas is already very large.

Of course, the ion channel and genome project that Yang Rui is working on now has a lot to do with genetic engineering in theory, but this is just a big profit. If you want to make a sheep with cloned embryos, you need to practice it. Really working.

Yang Rui accompanied his exhausted grandpa back to the hotel, but he couldn't sleep.

The next day, he sent his grandfather to the home of his comrade-in-arms. Yang Rui returned to the laboratory and immediately arranged for the scientific research dogs to search for information.

Whether you do it or not, the first step in understanding a field is always to search for information.

Several scientific research dogs put down their work without any choice, and began to search in the huge reference room and library.

The library of Peking University is still in the form of cards, on which are recorded the book titles, ISBNs and brief introductions. The scientific research dogs first searched for the cards according to various initials, and then rummaged aimlessly in the natural science library.

At the same time, some people took out the past journals and looked at them one by one.

This is the case with scientific research. Most of the work is repetitive manual labor, which can be done by any college student. However, the best and fastest are always smart people, so that this kind of work is done honestly and conscientiously. And clumsy children are still unwelcome.

Because the library is endless, you always have to think of a way to simplify your work. Sometimes, increasing the probability of luck is better than following the steps step by step.

After all, scientific research is not an isolated job, and competitors are everywhere.

That night, Yang Rui saw his competitor.

Dr. Wilmut's name appeared on the data sheet without any accident.

In later generations, the name of the father of the cloned sheep has already filled the ears of biology students.

But in 1985, Wilmut was still a little-known little researcher. The reason why he appeared in the data sheet was that he was the first to use frozen embryos to breed a calf. The time coordinate was 1973.

Yes,

As early as 12 years ago, Wilmut had already made the embryo transfer technology that China Animal Husbandry Corporation wanted, and he went a step further with frozen embryo transfer.

The difference between frozen embryo transfer and embryo transfer is like the difference between frozen egg IVF and IVF. As early as the 1990s, a large number of test-tube babies have been used in China. However, after freezing eggs, the technology of test-tube babies was still only available in a few hospitals until the 10s. From this we can see that both The technical generation is poor.

Of course, the frozen embryo transfer performed by Wilmüller is the first case, and it is also a laboratory product, which is still some distance away from commercialization.

However, as far as his achievements are concerned, he is actually not weak.

In 1973, Wilmüller graduated from Cambridge University with a Ph.D. Such an achievement was made shortly after graduation. No wonder he had the opportunity to run a laboratory in the 1980s.

This speed is also very fast in Europe and America.

In Yang Rui's impression, Wilmüller only had the idea of ​​cloning since the late 1980s.

The reason for this impression is that the prerequisite for mammalian cloning, the fusion of enucleated egg cells with the nucleus of early embryonic cells by means of electric pulses, was created in 1986, and it must have taken shape now, but it has not yet announced.

With this method, Wilmüller has the basis for cloning.

However, for scientific research, a year is already very fast.

Next year, Vermüller probably also has the idea of ​​cloning mammals.

In other words, if Yang Rui wants to do cloning, he will compete with Wermuller in scientific research.

This is not an easy task.

It’s not that Vermüller is so powerful. Yang Rui’s ability to obtain resources is extremely strong now—the nomination for the Nobel Prize is no joke. Coupled with the profitability of PCR and deferiprone, he can even get it directly from banks or pharmaceutical consortiums. Sponsorship, and with sponsorship, there will naturally be capital for competition.

Mammals, however, have deterministic periods of pregnancy.

You have completed the transplantation of the cell nucleus - this is a key step in cloning, but whether the mother can give birth to lambs or other animals, you have to wait for several months.

Yang Rui doesn't know how many times Wilmüller has tried, but he knows very well that even in the 2010s, cloning is still a very delicate, complicated and luck-intensive work, requiring a long-term collaboration of a capable team.

Can Ion Channel Lab or Sinovel Lab do it?

Yang Rui really didn't know.

Yang Rui's hesitation did not last for a few days.

When he led his grandfather up the Great Wall, visited the Ming Tombs, went to Tiananmen Square again, and paid homage to Chairman Mao's portrait for the second time, Yang Rui's BP machine rang.

Now, there are obviously more signal stations in the capital, and Yang Rui's BP machine finally has a place to play.

However, there were not many people who had seen the BP machine, and the people queuing up cast their eyes on Yang Rui.

Yang Rui looked at the number on the BP machine, but he didn't recognize it. After thinking about it, he put it down.

Comrade Yang Shan had sharp eyes and ears, waved his hand, and said, "I'll just line up by myself, and you can do your work."

Yang Rui shook his head: "It's not the phone number from the laboratory, nor the phone number from the school. It's the same if you call back later."

The queue in the memorial hall was very neat and solemn, but it was a crowded queue after all, so Yang Rui didn't care to leave his grandfather's side.

Yang Shan was not the kind of polite person. Seeing that Yang Rui was unwilling and did not force him, he continued to line up quietly.

"Leader, do you need to use the phone?" A staff member of the memorial hall quietly approached Yang Rui, startling him.

"You walk without sound?" Yang Rui's heart beat fast, where is this place, you walk without sound, how many people will you scare to death?

The staff of the memorial hall froze for a moment, then came to their senses, and hurriedly said, "I'm afraid I'll disturb you, I'm sorry."

"fine."

"Oh, leader, we have a phone in the office, you can use it anytime if you need it." The staff pointed to the BP machine on Yang Rui's waist and said.

Suddenly, Yang Rui said, "I'm not the leader, so you don't have to be polite."

"It doesn't matter, it can be used even if it is not a leader, the people's phone is for the people."

"You can really talk, but I'm really not a leader." Yang Rui defended again, and said: "I'm here with grandpa. I'll go out and make a call when the line is up."

"It's okay, you can go to our office with grandpa to rest for a while, and we will arrange for you to pay homage to the portrait later, and there will be no delay."

The other party's attitude was cordial and sincere, but it was hard for Yang Rui to refuse.

"Okay then, thank you." Yang Rui turned his head to ask for advice, "Then shall we go there?"

"Okay." Yang Shan strode out of the queue.

Yang Rui followed behind the slender staff and enjoyed a privileged treatment.

I have to say that the privileged treatment is really convenient. Not only did he answer the phone in his office, he didn't pay a dime for the phone bill, but he also joined the queue when he left the office. limited time.

People in line, even those who are about to arrive, don't seem to object to such a line-jumping behavior. As an old revolutionary, Comrade Yang Shan has always been strict with himself, but he seems to have no problem with jumping in line.

After looking up at the portrait, Yang Shan was a little tired, and the staff who had been following Yang Rui immediately said: "Mr. Yang, why don't you sit in our lounge for a while, and I'll make you a cup of tea. If the old man is sleepy, just squint." For a while, we have blankets, so we won't catch a cold."

Yang Rui immediately felt the meaning of hospitality that cannot be given up.

"Okay, thank you." Yang Rui helped his grandfather to the lounge of the memorial hall, and saw two more good-looking waiters appearing, offering tea, snacks, thin quilts and pillows at the price of water. The large lounge is simply decorated, but reclining chairs, TVs, radios and other things are all available.

"The quilt covers and pillow covers are all washed and steamed." The service staff smiled without showing their teeth, and retreated after laying out the lounge chairs.

Seeing the door being gently closed, Yang Shan couldn't help feeling: "You said that the service in Beijing is different, so caring. It's not like the waiters in Nanhu City, whose nose is not a nose, and eyes are not eyes."

Yang Rui moved the corner of his mouth, he had nothing to say in front of the hard facts.

Not long after, the BP machine rang again, Yang Rui called again, and simply invited him to the memorial hall.

Wen Zelin wasn't the only one who came, Ding Shiyi, Jiang Zhijun and Jiao Changchang all followed.

Seeing this scene, the staff of the memorial hall felt more and more that they had made the right decision, and they were extremely attentive in serving tea and water.

Jiang Zhijun looked around and sighed, "I've seen a lot. This is the first time I've seen people in the memorial hall."

Yang Rui was a little embarrassed: "I came here with grandpa, it just so happens, you guys drink some tea first, I'll find someone to pick up grandpa back, and we'll sit down and talk."

"Don't be so troublesome, I think so, let's go out and find a place to talk for a while, and let my orderly stay here to watch. When the old man sleeps well and sleeps comfortably, let's drive back together and continue talking at your place." Ding Shiyi deliberately lowered his voice and called his orderly over.

The orderly is a bright young man, wearing a military uniform and carrying Ding Shiyi's briefcase, which is reassuring to look at.

Yang Rui nodded his head in agreement, and told the people in the memorial hall. After he went out to take the car, he went to the front door and sat down.

"We talked with Lao Jiao, and we think this business can be done, and we want to partner." Ding Shixi said the purpose before the tea was brewed.

Jiang Zhijun couldn't help laughing: "Old Ding, you don't talk about things like this."

"Ding is Ding Mao or Mao, it's meaningless to talk about it. Yang Rui, please express your opinion." Ding Shiyi's style is rough, but the effect is good.

Yang Rui was stared at by several people, thought for a while, and asked first: "Are you all going to go to sea?"

"Depending on the situation, if someone needs to manage it, Xiaowen should go, otherwise, we will find someone to name it." Ding Shiyi said without any cover-up, making several people roll their eyes.

Various images of government-business collusion emerged in Yang Rui's mind.