Since 1981 Health School

As a doctor, I tried my best, but the ending is still not happy, and this is beyond the control of the doctor.

Chen Qi doesn't have time to feel sorry for other people's wives anymore, because he received a call that something happened to his own wife.

Lan Lijuan is also an awesome character.

When the drug omeprazole sponsored by Asrila was brought to China by Professor Segel from Karolinska University Hospital in Sweden, Lan Lijuan couldn't help it.

The People's Hospital has specially set up a "six internal departments" for this stomach disease research group, and Lan Lijuan is also the deputy director of the department.

However, there is a lot of preliminary work to be done on the composition of department personnel, laboratory construction, and research group structure.

There is another doctor who changes to another doctor and treats the patient as a guinea pig first. Good and bad, illness and pain are all borne by the patient.

There are not a few such doctors, and many clinical drugs are actually experimental drugs needed by the research group, even in 2022, this situation will still exist, especially in rare disease or cancer patients.

Doctors want to experiment with drugs not only for curative effect and results, but also to monitor serious side effects such as adverse reactions.

Therefore, whether the patient is cured or cured, it has practical clinical significance, but the patient has to bear all the consequences.

But Lan Lijuan is not such a quack doctor, she has a strong desire to experiment on her own body first.

The problem now is that Lan Lijuan has checked several times and found that there is no unknown bacillus (Chen Qi calls it Helicobacter pylori) on her gastric mucosa, so she can't "feed the tiger with her body".

in the lab.

Professor Segel, Professor Zhang Chunyi, and Lan Lijuan, who had just arrived in China, sat together and discussed how to carry out clinical work.

Segel thinks Huaguo is really a paradise, why?

Because if he wants to conduct a clinical project in Sweden, he must first find the father of the funder, then report to the competent health department, and ask the upper management of the hospital for approval.

It is not enough to go through layers of approval. Patients must have the right to informed consent before the experiment.

The research group, which has worked so hard to prepare, will face the end of a patient refusing to participate.

It doesn't cost money to treat people, and it's not short of money, so why take a certain risk to participate in clinical trials? What if it dies or becomes useless?

Well, even if you successfully carry out the clinical trial, you must be extremely careful, and all the documents must be prepared, and the documents signed by the family members and the patients themselves are complete.

Moreover, the whole process must be strictly followed the reporting process, and there must be no mistakes, otherwise the consequence will be the intervention of the Medical Ethics Committee.

The most frightening thing is the patient's lawsuit. If it works, it's okay to say, but if it doesn't work or has side effects, the patient will definitely sue and sue you.

Once this kind of prosecution is lost, the fine will definitely make your doctor bankrupt.

It is useless for you to sign the informed consent form. The rogue lawyers will exploit countless legal loopholes to find your procedural errors, and then accuse you of obtaining the patient’s consent by deception, and the agreement should be voided.

This is why developed countries in Europe and the United States like to do clinical drug trials in poor countries in Asia, Africa and Latin America, including genetically modified products.

As a result, Professor Segel was dumbfounded when he arrived in Huaguo. Why did he come more than 2 months late, and the Vietnam-China department has even established a department?

The foreigner had to give a thumbs up and shouted "Yakesi", oh wait, it should be shouted "Nas".

The three partners in the research group originally discussed that Professor Zhang Chunyi would be in charge of outpatient admissions, and Lan Lijuan would be in charge of the ward.

Professor Segel and his team are conducting laboratory follow-up research.

But there is also a question here, what kind of patients are you going to treat? We can't take in all the patients with stomach pain, can we?

You must know that the quadruple therapy that Chen Qi secretly revealed is not effective for all stomach diseases. Of course, it is necessary to carry out clinical drug trials in a targeted manner.

But all of this has no experience.

Before Lan Lijuan and Zhang Chunyi searched for Helicobacter pylori in gastric mucosal specimens of patients with gastric diseases in internal medicine, the positive rate was still very high.

But there is a prerequisite for this. There are about 50 patients in a department, and not everyone has the financial ability to do gastroscopy.

Gastroscopy was a rare commodity in the Yuezhong area in 1986, even in the provincial capital. The high examination fee alone stopped many patients.

Generally, only patients with severe stomach problems or those with strong financial strength will undergo gastroscopy and microscopic biopsy.

So how to select patients, how to determine which patients are suitable for the research group?

The most critical point is whether clinical medication has any effect? How long does it take to take effect? How does the process work? How to explain to patients and family members?

Chinese people are easy to bully, but as a Sino-foreign cooperation project, and Lan Lijuan and Zhang Chunyi are doctors with a bottom line, of course they want to get first-hand information.

How to grasp this first-hand information was placed in front of the three of them.

Lan Lijuan gritted her teeth and said:

"I have a suggestion. Currently, we have a lot of cultured samples of Helicobacter pylori in our experiments, so I think I can swallow these bacilli so that we can fully observe how Helicobacter pylori causes disease and how it destroys the stomach. mucous membranes.

After we get the first-hand information, we will carry out targeted treatment. Not only can we test the effects of omeprazole and antibacterial drugs, but we can also track the changes in the gastric mucosa throughout the process. From the onset to the cure, we can grasp the first-hand information . "

When Lan Lijuan said this, not only Professor Zhang Chunyi and Professor Segel were stunned, but even the little doctors from China and Switzerland in the conference room were all dumbfounded.

Drinking bacteria grown in a lab?

Just thinking about it gives me goosebumps.

And it's not only disgusting, but also very dangerous. Where are bacteria and viruses so easy to touch? Don't forget the Unit 731 back then.

Professor Zhang Chunyi looked at his student and was the first to object:

"No, I don't agree with you to do this. What if you have an accident? Any unknown bacteria or viruses are uncontrollable."

Professor Segel also objected: "Lan, I know that I look like a great doctor, but this is too risky. We can definitely pay patients to drink bacteria. I believe there will always be someone willing to help."

Foreigners speak so directly, just use money.

Lan Lijuan is a very thoughtful person, even Chen Qi can't change the things she decides.

I saw her smile, and said easily:

"Mr. Zhang, Professor Segel, in fact, before the meeting, I have taken a specimen of Helicobacter pylori orally."

"what?"

"what"

Professor Zhang was terrified, grabbed Lan Lijuan's hand and blamed eagerly:

"You son of a bitch, why are you so courageous? If something happens to you, how can I explain it to Comrade Chen Qi?"

Lan Lijuan smiled, with a relaxed expression:

"With you and Professor Segel here, there is no stomach problem that I am afraid of. I believe you can help me cure it. Now is not the time to be surprised. Let's hurry up and start the project.

I have saved the gastric mucosa specimens before oral administration of Bacillus, and now I need to study the changes of the gastric mucosa on the first day after Helicobacter pylori infection, come on, everyone act. "

The established fact has been created, everyone is a high-level intellectual, reason overcomes emotion, and immediately starts to work.

Lan Lijuan has changed from a doctor and a researcher to a patient, and she has to endure the pain of gastroscopy every day.

Gastroscopes in the 1980s were relatively primitive, with a thick and long tube inserted into the stomach, and there was no TV screen to track the whole process.

Doctors who do gastroscopy must look at it with their eyes, just like looking at the lens of a SLR camera.

After reading it, there are no computer screenshots, and everything has to be recorded by hand.

This time, Professor Segel brought the most advanced gastroscope in Sweden, with a camera attached to the other end, which can take partial images in the field of view, which is very helpful for scientific research.

After Lan Lijuan took Helicobacter pylori orally, she didn't feel much on the first day.

The next day, apart from a little nausea and nausea, there was no pain.

This made the members of the tracking research team a little confused, and at the same time they began to worry.

If Lan Lijuan never gets sick, does it mean that Helicobacter pylori is not pathogenic? No damage to the gastric mucosa?

Then the research team will be in great trouble. Aslila has reason to suspect that this is an act of defrauding scientific research funds. At the same time, Dr. Hua Guo, together with Professor Segel, will become a joke in the international medical circle.

Others are not as anxious as Lan Lijuan.

She is the initiator of the research group and the discoverer of pylori bacteria. If it turns out that the direction of the research group is wrong, then she will really have no face to face Jiang Dong's elders.

As for the other members of the research group, they are all young and middle-aged backbone technical teachers or doctors from Haidong Medical University. They came to Yuezhong People's Hospital because of the high subsidies of the research group.

If your research group is disbanded, then they will suffer a great loss. I don't know when the plan to change the color TV will be realized.

Just when everyone was anxious and looking forward to it, it finally lived up to expectations.

On the third day, Lan Lijuan had a stomachache, which suddenly started in the middle of the night. There was a burning sensation in the stomach, and the pain radiated to the back.

The symptoms are similar to those of a myocardial infarction. If Lan Lijuan was not a professional doctor and took Helicobacter pylori orally, she would definitely have to do an electrocardiogram overnight.

Lan Lijuan is a very strong woman, even if her stomach hurt woke her up, she didn't say a word.

Instead, I kept feeling the feeling, characteristics, regularity, and accompanying symptoms of this stomachache in my mind, and then quietly got up, turned on the desk lamp, and recorded it in the draft notebook while hunched over enduring the pain.

At this time, Chen Qi was fast asleep on the bed.

Lan Lijuan knew that Chen Qi was worried about the mother and child cancer patients during this time, so she didn't intend to wake him up.

Some people say that a doctor should not marry another doctor when marrying a daughter-in-law, but should choose another profession. In fact, in real hospitals, doctors prefer to find spouses who are also medical staff.

Why?

Because doctors are too busy, going to work, working overtime, night shifts, endless books, endless shifts, and endless surgeries.

Therefore, it is best for a doctor's spouse to be in the same industry, so as to understand each other and avoid many conflicts between husband and wife.

It's like Lan Lijuan's stomachache is so bad that she can't sleep now, and another woman is sick. Seeing her husband sleeping like a dead pig, she must be unhappy.

Sven's point was to pout his mouth to sulk.

The savage one kicked her husband off the bed and cursed: "You don't love me anymore, you don't care about me at all, why did my old lady marry you when she was blind?"

When medical personnel form a family, at least there will be no misjudgment. It will not happen that you are busy at work and stay out at night, but your wife thinks that there is someone outside? Are you not going home?

Of course, there are also disadvantages, that is, it is difficult to hide selfish money secretly, because when you pay your salary and how much you pay, your wife may know better than you, because your salary is stuck in her hands...

The next day, before dawn, Lan Lijuan packed up and was ready to go out.

Before leaving, she ran to the elder sister's room to see the twins.

Regardless of whether Chen Qi and Lan Lijuan were voluntary or forced, they had already become very busy people and were away from home all day long.

Chen Yixin and Chen Yiyi usually rely on the eldest sister and Mao Xiaolian to take care of them, and they are well-fed and fat, which is very worry-free.

When the silly elder sister saw her brother-in-law coming in, she thought something was wrong, so she hurriedly got up: "Lijuan, what's wrong, you have to go out so early?"

Lan Lijuan kissed the two babies, smiled and said:

"Sister, our department has a lot of things going on recently, so I have to go to work early, it's okay, you go to sleep first, and wake Chen Qi up later."

The silly elder sister looked at the gray sky outside, and complained a few words:

"You two, you are so busy that you don't even have a day off, but your heart and mind have protested to me several times, arguing for your parents."

While pulling the quilt for the two twins, Lan Lijuan sighed softly:

"When I finish this work, next week, Chen Qi and I will take them to the children's park to play."

The silly elder sister muttered: "Next week, next week again, I don't know how many next weeks, you husband and wife are taking care of the hospital."

On the second floor, Chen Qi turned over on the bed, felt that his wife was not there, tilted his head, and fell asleep again.

After Lan Lijuan came to the "Sixth Internal Medicine Department", she immediately copied her symptoms from last night into the experiment calendar, and then prepared a full set of gastroscopy equipment by herself.

When everyone went to work at 7:30 in the morning, a gastroscopy was performed immediately.

Professor Segel operated it himself. After all, he brought such an advanced gastroscope, which is not available in China, and only he can play it well.

While manipulating the handle, he looked with his eyes, and then suddenly shouted in surprise:

"Here everyone, now Dr. Lan's gastric mucosa has been extensively congested and edematous, and there is still a little erosion in this area, and tiny nodules can be seen in the gastric antrum. This is not there when we observe tomorrow. Will this be related to HP? Infection related?"

Professor Zhang Chunyi took a gastroscope and observed it carefully, and shouted excitedly:

"There have been changes, and the changes have been very large. Now I will take another mucosal biopsy. If it is confirmed that there is Helicobacter pylori on it, it can 100% restore and confirm the damage and pathogenicity of this bacillus to the gastric mucosa."

At this time, the members of the research team took turns to observe the past, but forgot to observe that Lan Lijuan's face was getting paler and paler.