Start as an Emergency Physician

Generally white struggled.

Zhou Yuan pressed its head, and then carefully disassembled the gauze.

The claws under the gauze scratch restlessly, and the sutures are visible to the naked eye, but they already have the first signs of survival.

Zhou Yuan carefully checked it again.

The distal veins are unobstructed, the capillary circulation is normal, and the nerve reflexes are somewhat obtuse, but there is no problem at all.

Zhou Yuan moved away to look at Dabai and Xiaobai again.

Although the efficacy is inconsistent, the final result is the same, the paw after transplantation... Perfectly alive!

In other words, the surgery is completely doable!

Zhou Yuan stood up with some excitement.

Right now...... Only one patient is needed to prove this theory!

If successful, then this operation is likely to go down in the history of the medical community in the field of amputated limb replantation...

For the sake of accuracy, Zhou Yuan changed the position of the other two front and rear paws of the three mice overnight, and then gave the mice seven or eight potato chips.

Pig: I'm so hard.

After three times in one night, Zhou Yuan was also a little tired, looking at the three mice lying on the table, Zhou Yuan showed a satisfied smile.

The three surgeries went smoothly, and if nothing else, the limb transplanted by the mice should also be able to survive.

Of course, we will have to wait until the evening to see the initial results.

Zhou Yuan quickly washed up and glanced at the date.

Yes, it's Monday, and today I did go to work by myself.

After walking for about ten minutes, Zhou Yuan arrived at the emergency department.

Liu Kai and Haiyang also happened to go to work, and when they saw Zhou Yuan, they greeted them warmly.

"Senior Brother Zhou Yuan, I looked at the duty schedule yesterday, wasn't Director Liu on duty in the morning, why were you sitting in the clinic when I went to change shifts?" Liu Kai was a little puzzled.

I just said that I felt that something was wrong, and I thought I had misremembered the schedule.

Zhou Yuan's mouth twitched: "I'll help Director Liu take a shift." "

Liu Kai frowned, "Director Liu has just been sent to the operating room, it seems that he wants to take bone marrow, and I don't know who it is for." "

"Don't say it, the master is here!" Haiyang glanced behind him in a panic and was about to run back to his office.

Zhou Yuan also looked over, He Jianyi was rushing out of the office and hurriedly rushed to the operating room.

"What are you running in the ocean, I'm not catching you for being lazy. He Jianyi glanced at it helplessly.

Zhou Yuan instinctively became vigilant and followed He Jianyi to the operating room.

"Teacher, what happened?" asked Zhou Yuan.

He Jianyi's face was serious, "I can't pull out the bone marrow!"

"Director Liu?"

"Yes, now her daughter Haoyue is already lying in the transplant warehouse waiting for the marrow, if she can't extract the bone marrow from Liu Huimin's body, Haoyue has life"

Zhou Yuan's face also became serious.

Before hematopoietic stem cell transplantation, patients generally undergo long-term chemotherapy, which will cause irreversible damage to the body.

The previously destroyed hematopoietic stem cells were transfused back into the body and barely survived.

Because, in addition to Liu Huimin's bone marrow matching with her, it is too difficult to find a second suitable bone marrow match...

To undergo a bone marrow transplant, the donor and patient must have a pro-HLA match. There is a 1 in 4 chance that the HLA will be fully compatible in siblings, while in the Celestial Empire, the chance of HLA matching in unrelated blood donors is only a few in 10,000 to 100,000.

And, one more point worth mentioning.

HLA is located on chromosome 6 in humans. Like other chromosomes, chromosome 6 is a pair, one from the father and one from the mother.

So, half of our HLA genes are the same as those of our parents. In other words, our parents and we are both 50% identical in terms of HLA.

This is a bone marrow that is not fully matched, and it is generally not used because it will lead to an increased incidence of postoperative complications, rejection, etc.

Since Haoyue has come to the step of seeking Liu Huimin's help, it means that her condition can no longer wait, and choosing to transplant Liu Huimin's bone marrow is already a last resort.

It can also be understood that if the bone marrow transplant fails this time, Haoyue's life will be declared over.

"What are you doing here, can you do a bone marrow transplant?" He Jian tilted his head and asked.

Zhou Yuandao: "I have learned a little. "

He Jianyi: "..."

"Keep up!"

Zhou Yuan asked, "Which method of hematopoietic stem cell extraction does Director Liu use?"

"Peripheral blood stem cell transplant!"

"Isn't it a classic bone marrow transplant?" Zhou Yuan frowned.

In fact, there are three methods for the treatment of leukemia to extract hematopoietic stem cells, the first is simple and crude bone marrow transplantation, the second is the peripheral blood stem cell transplantation that Liu Huimin is currently doing, and the third is umbilical cord blood stem cell transplantation.

Peripheral blood stem cell transplantation uses a mobilizer to release hematopoietic stem cells from the bone marrow to the peripheral blood, and then collects hematopoietic stem cells from the circulating blood through a blood cell separator.

Compared with bone marrow transplantation, this type of transplantation has the advantages of convenient collection, no need for anesthesia for the donor, and faster recovery of hematopoiesis after transplantation.

In addition, the incidence and severity of postoperative graft-versus-host reactions are reduced.

However, peripheral blood stem cell transplantation is a recent technology that has not yet fully matured, so there may be many drawbacks and undiscovered dangers.

Today, Liu Huimin encountered one of them.

The two of them quickly made preoperative preparations, washed their hands and disinfected their hands in seven steps, and then entered the operating room and put on surgical gowns.

Originally, peripheral blood stem cell transplantation did not need to go to the operating room, just like blood drawing, it could be completed on the hospital bed, but because Liu Huimin's hematopoietic stem cells were not extracted, they were sent to the operating room.

"Haven't you drawn it yet?"

He Jianyi took Zhou Yuan to the side of the operating bed.

"Not yet! only a handful of hematopoietic stem cells! We've almost had a round of peripheral blood draws!" said the hematology doctor anxiously.

He holds a special blood cell separator in his hand, with blood drawing on one side and a reflux device on the other.

Because only hematopoietic stem cells are needed, this device will leave the absorbed hematopoietic stem cells, and the blood cells will be sent back to the donor through the reflux device to minimize the harm to the donor.

"Didn't the mobilizer get enough, why didn't the hematopoietic stem cells enter the peripheral blood?" He Jianyi asked seriously.

"Enough is enough, we were giving mobilizers every day for a week before the bone marrow transplant, but who expected that the stem cells in the bone marrow were not discharged!"

Liu Huimin, who was lying on the hospital bed, was pale at the moment.

Although the large amount of blood drawn and refluxed did not reduce the total amount of blood in her, the damage to her body still existed.

"Don't smoke it, let's have a bone marrow transplant... I want to save my daughter. Liu Huimin's voice rang out.

"A bone marrow transplant... I can't do it," said the oncologist in despair.

"Why?" Liu Huimin's face turned even paler.

She is a doctor in the emergency department, and she only has a general understanding of this knowledge, but she also knows that peripheral blood stem cell transplantation is not possible and can be replaced with bone marrow transplantation!

Why can't it be now..._

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