Supreme Pharmacist System

Office of the Cryptococcal Disease Research Institute.

"Hello Zhou Suo, I have been friends with you for a long time, and today I finally saw a real person."

"Haha, it's the same! I've admired you, Director Zhang, for a long time, and I've always wanted to visit you, but unfortunately it never happened."

Zhang Wen held Zhou Wen's hand and said with a smile, "If I knew you would go to Zhong Hai last time, I would never go on a business trip."

Zhou Wen laughed loudly, "That won't do, it will be a sin if it delays your work."

Although the age difference between the two is more than 20 years, they both hit it off, cherish each other, and chatted quite speculatively!

In addition to the titles that the public is familiar with, Zhang Wen is the director of the Department of Infectious Diseases of Huashan Hospital, the director of the Department of Internal Medicine of Futu University School of Medicine, and a doctoral supervisor. He also has another identity—a biomedical researcher at Futu University.

Don't underestimate the identity of this biomedical researcher. Zhang Wen's main research direction is microbiology.

All his achievements can be said to come from microbiology.

"Come on, Zhou Wen, don't patronize Zhang Wen, let me introduce you, this is Pan Renfeng, director of the Department of Infectious Diseases at Harmony Hospital."

"Hello, Mr. Pan..."

In the laboratory in the morning, when these big shots came over, Zhou Wen didn't have time to get to know them one by one.

Unlike those academic elites in China who are busy with political life, the ones here today are all academic bigwigs who are really working on the front line.

Everyone is very outgoing and approachable.

After a brief greeting, everyone's topic naturally quickly focused on the neutralization effect test.

Everyone discussed enthusiastically.

...

...

News of the successful isolation of antigenic B cells by the Cryptococcal Disease Research Institute of Jiangzhou Hospital spread like wildfire.

As soon as the news came out, it immediately attracted the attention of the domestic medical community.

Before the domestic medical community reacted,

The latest news also revealed that it is not just as simple as the successful separation, but has been successfully amplified and expressed antibodies.

Now it's not just as simple as paying attention, but one after another began to inquire about the truth of the matter.

But at this moment, Jiangzhou Hospital announced that the antibacterial cells had passed the neutralization test.

One stone stirs up a thousand waves!

Now everyone can't sit still.

After passing the neutralization effect test, in other words, the next step is to start clinical testing. As long as there is no rejection or major side effects, it can be officially launched on the market as a Cryptococcus neoformans vaccine.

This is great news.

According to the latest research in the Proceedings of the National Academy of Sciences of the United States, infections caused by cryptococcosis neoformans cause about 1 million deaths worldwide each year, of which about 600,000 are in sub-Saharan Africa.

Cryptococcus neoformans enters the human body mainly through the lungs and can be distributed throughout the body, including the brain.

The result of the infection is cryptococcosis, which causes chest pain, dry cough, bloating, headache, blurred vision, or confusion. This infection can be fatal, especially if it is not treated with antifungal infections.

Even with treatment, the mortality rate is as high as 30%.

Very scary!

Soon, health organizations in many countries called, and even the World Health Organization called for consultation.

In addition, some large pharmaceutical groups and research institutes have also called to inquire about the technology of isolating antigenic B cells...

The successful replication of antibacterial cells is of great significance.

...

While the global medical community is paying attention to this matter, Jiangzhou University School of Medicine and Tanzhou University School of Medicine are also discussing with Zhou Wen about the patent ownership of some technologies.

At the beginning of Jiangzhou Medical College, they didn't expect Zhou Wen to successfully replicate antibacterial cells. The main purpose was to use Zhou Wen's influence on prions to increase the influence of Jiangzhou University Medical College.

The same is true for Tanzhou Medical College. In fact, the purpose is similar. It is best to be successful, and to earn academic fame if not successful.

But never expected that Zhou Wen would succeed.

This really doesn't make sense.

Now that it has been successful, there is no need to say more about the halo and honor, but they are all superficial things.

But the issue of core interests is also very important.

That is the issue of patent ownership.

The anti-cryptococcal vaccine involves at least 5 to 10 patented technologies, each of which can bring long-term and huge benefits. This must be made clear as soon as possible to avoid unnecessary disputes in the future.

Although Zhou Wen didn't want to talk about such naked things as soon as the results came out, he had no choice but to come because the leaders of the two universities were anxious.

Jiangzhou University School of Medicine, conference room.

Chen Tongguang, director of the medical department, said: "Professor Zhou, you are the main person in charge of the project, tell me your opinion!"

Zhou Wen said straight to the point: "Okay, then I will talk about my opinion.

The Institute of Cryptococcosis was established with the support of the leaders, and the two parties had an agreement before, so I think it is enough to allocate according to the agreement.

After the follow-up vaccine clinical trials and market sales, 90% of the costs and benefits incurred will be shared equally between Jiangzhou University and Tanzhou University, and the remaining 10% of the benefits (excluding clinical trial costs) will be shared by all our experimenters. distribute. "

Lu Yongfeng, director of Tanzhou University School of Medicine, asked: "Of course we know this. What about other patents?"

Zhou Wen asked strangely, "What other patents are there?"

Lu Yongfeng smoked a cigarette and said, "Cell separation technology, amplification technology, measurement technology, and primer design data, etc., should these all be included?"

Zhou Wen glanced at Chen Tongguang and asked, "Director Chen, is this the result of your discussions?"

Chen Tongguang said helplessly, "This is not what the medical department wanted, it was proposed by the school."

Zhou Wen nodded and said, "Okay! Then I'll just say it straight. Except for the vaccine, all the other patented technologies are owned by me personally. I have already made it clear when I was the deputy director of the research institute. And it’s written in black and white in the contract.”

Lu Yongfeng smoked a cigarette and said slowly: "You can't say that! The contract belongs to the contract, but you can't ignore the facts.

The vaccine was indeed developed under the leadership of Professor Zhou, but in the process, other researchers also put in hard work and sweat. You can't take all the benefits by yourself, but others have nothing, right? ? "

Zhou Wen frowned, "What do you mean I took all the benefits by myself?

Without me, does Director Lu think that antigenic B cells can be isolated?

Without me, Director Lu thinks the sequence amplification can be successful?

Without me, does Director Lu think a vaccine can be developed?

When we speak, we must not only respect the facts, but also rely on our conscience, let alone ignore the facts! "

Seeing that the atmosphere in the conference room was a bit tense, Secretary Liu from Tanzhou University who came to preside over the negotiation, said with a smile: "Professor Zhou, don't be angry and listen to me.

It is a good thing that the vaccine has been developed. There is still a lot of work that needs to be presided over by Professor Zhou. Let's talk about it calmly. "

After a pause, he said: "See if this works. Let's take a step back. Professor Zhou can just take out the separation technology and amplification technology, and the rest will be yours."

Zhou Wen smiled and said, "Secretary Liu, do you think it's possible?"

After a pause, Zhou Wen followed up: "At the beginning, Director Cheng asked me for Cryptococcus mutans serum, and I gave it without saying anything. Later, your Xiangya Hospital successfully cured Cryptococcosis neoformans and won countless honors and applause.

But I was criticized for this and my bonus was deducted!

Later, your Xiangya Hospital wanted to establish a cryptococcal disease research institute, and you specially asked me to be the first person in charge of the project. I was unwilling, and it was your leadership who repeatedly invited me to agree.

It also agreed to give 90% of the proceeds to the medical schools of both parties.

Now let me take a step back.

I'm sorry Secretary Liu, I can't take this step back today. "

Saying that, Zhou Wen stood up, "Either follow the contract, or sue me!"

After speaking, Zhou Wen turned around and left, leaving a room full of people looking at each other in blank dismay.

...

Jiangzhou Hospital Testing Center, PCR group.

In the office, Zhang Shuguang, Yang Liqun, and Wang Huiyao were chatting.

Because Zhou Wen left, Zhang Shuguang couldn't find a successor, so he has been concurrently serving as the leader of the PCR team.

As for Wang Huiyao, he and Yang Liqun are good friends, and they came here specially to see him today.

"It's a pity that kid is gone." Zhang Shuguang said while smoking a cigarette.

Yang Liqun smiled and said, "I don't think it's a pity! If he was still in the PCR group, how could he grow to this point?"

Wang Huiyao was also smoking a cigarette and said with emotion: "Yes! His talent in biology is something I have only seen in so many years, and it can be called unprecedented."

Yang Liqun said: "I think it's normal! The vast majority of geniuses are teenagers who become famous.

For example, Newton was only 24 years old when he discovered the three laws, the law of universal gravitation, and calculus, Einstein was 28 years old when he discovered the theory of relativity, and Schrödinger was only 26 years old when he proposed glass dynamics. Who else is coming? "

Zhang Shuguang continued: "Heisenberg discovered the uncertainty relationship at the age of 26, Bohr proposed the hydrogen atom model at the age of 28, and Josephson predicted the Josephson knot at the age of 24."

Wang Huiyao nodded, and then added: "Anderson seems to have discovered the positron at the age of 22, and the youngest Nobel Prize winner is Bragg, who seems to be only 21 years old."

After Wang Huiyao finished speaking, Yang Liqun followed up, "And Maxwell was 24 years old when he discovered the laws of electromagnetism."

Zhang Shuguang said: "Tell me, why is this?"

As soon as he finished speaking, Zhou Wen's laughter came from the open office door, "Because when a person receives a large amount of cutting-edge knowledge in the shortest possible time, he is most likely to discover something.

At this time, the constraints are small, the thinking is quick, and the most critical and useful information can be found from a large amount of intricate information.

And if you use a step-by-step approach, you may gain a lot. All knowledge points are well-founded and logically rigorous, but at the same time, thinking inertia is generated, and it is difficult to make breakthrough discoveries!

As you get older and experience more, you think less and less.

Because in many cases, experience can replace thinking, in this way, there will be fewer and fewer problems, and experience is always the first to solve problems, and in the end, basically no new questions can be raised, and there will be no new discoveries..."

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