The Goddess Shines on America

When everyone finally returned to school, it was already a quarter past nine in the middle of the night.

"There is no business that is more profitable than pharmaceuticals!"

Ashley jumped up and down at the front of the group of four, because what she encountered today made her unable to calm down: "Think about the income of the profession, surgeons, dentists, they are all firmly in the The top two in the entire American career rankings!"

"But this industry is not so easy to set foot in, Ashley, you must be calm."

Although she was persuading, Alice was still satisfied to see that the three friends were all in high spirits. Good friends have to share blessings, Alice owns a lot of properties, and basically give them some shares. In other words, if she really sets foot in the pharmaceutical industry and earns a lot of money, Ashley and others will also be the direct beneficiaries.

Therefore, they naturally have a lot of suggestions, just as Maiya said immediately: "It is not easy, the pharmaceutical industry is considered a traditional industry all over the world. Then Alice, you are very interested in this industry." How much do you know? Have you done any research?"

Alice immediately gave an affirmative answer: "Don't worry, I checked it when I asked Delof to start researching the I virus..."

Sissy muttered, "I, Virus, what a stupid name."

"...Ahem, but before that, let me give you a brief introduction to the market situation in the pharmaceutical industry around the world."

This is very important information. For a while, Sissy stopped complaining, and everyone stared at Alice.

"Five of the top ten pharmaceutical companies in the world belong to the United States. The No. 1 is Pfizer, a multinational pharmaceutical company based on research and development with a history of more than 120 years. Its headquarters is located in New York, There are three main business areas, namely pharmaceutical health care, animal health care, and consumer health care products. Speaking of the most famous products... Ashley, do you think it sounds familiar?"

"Viagra! Brother Wei! Huh~ha! Alice, why don't we buy this company directly!"

"Bitch, that's for men, what do you mean?"

"Oh~ Sissy~ I'm your man~"

"Don't come over here! Don't make that weird accent! Hey!? What are you doing!? Alice stop her~!"

Even if you close your eyes, you can conceive the picture in your brain, not to mention that Alice watched their farce with her own eyes. She laughed and hugged Sissy's shoulders. : "Hehehe~ I said Maiya, don't you stop it?"

Now that she was called, Maiya stepped forward with one easy step, grabbed Ashley by the collar with one hand, and dragged her away like a chicken.

"You bastards are pretty good at interrupting me."

Looking up at the sky for a moment, Alice shook her head: "Continuing the previous topic, Johnson \u0026 Johnson, the second largest company in the world, has a history of just one hundred years since its establishment, and it is also a comprehensive super large enterprise. Of course, among these leaders The gap is always changing, although it has been ranked second in the past two years, it is possible to rush to the first place in a few years, and it is not a fixed thing.”

"The Sanofi-Aventis Group, a joint venture between Germany and France, is the third largest pharmaceutical company in the world and ranks first in Europe. It holds a leading position in seven major therapeutic areas, namely cardiovascular disease, thrombosis, oncology, and diabetes. , central nervous system, internal medicine and vaccines. At present, its business has expanded to nearly a hundred countries, of course, this is not unrelated to the geographical location, "

"Furthermore, the Swiss company Jiaji is also large in scale and has a very long history. As early as 1758, Mr. Jiaji was operating chemicals, dyes and medicines in Basel, Switzerland. Later, the family business grew and became this Swiss company. First, the world's leading pharmaceutical behemoth."

"Well... There is another company in the UK called GlaxoSmithKline. It represents the highest level in the world today in the four major medical fields of anti-infection, central nervous system, respiratory and gastrointestinal metabolism, and ranks first in the industry in the field of vaccines. .In addition, the company also holds a leading position in the world's consumer healthcare market, with products including over-the-counter medicines, oral care products and nutritional health beverages."

"If there is one company in the United States that stands out to me the most, it is Wyeth. It is one of the world's largest research-based pharmaceutical and health care products companies, headquartered in New Jersey, USA. It has a strong presence in prescription drugs and It plays a pivotal role in the research, development, manufacture and operation of over-the-counter drugs, as well as in vaccines, bioengineering, agricultural products and animal health products.”

After a long speech, seeing the stunned looks of the three friends, Alice shrugged and said: "So you see, they are all super giants with a century-old level and a global scale. If I rashly take I For the finished medicine of the virus, just open a pharmaceutical factory and prepare to sell it, and every second is the rhythm of being acquired."

"Then, we need to take one step at a time."

While walking slowly, Maiya thoughtfully analyzed for Alice: "Alice, do you understand the procedures and preparations required to open a pharmaceutical factory?"

"The problems of company registration and location selection are the same for all companies. The medical industry needs to pay attention to the FDA."

In a very methodical manner, Alice said to her partners: "As the saying goes, the U.S. Food and Drug Administration, no matter whether we plan to sell medical equipment or directly take drugs, we have to pass their supervision and management. At this time, If entrepreneurs can get to know government officials in relevant departments, it will often save a lot of time and energy. Obviously, our dear Vice President Bush, can help at this time, as long as I invest a few shares in his son's oil company Millions... ahem, you understand."

"FDA has a complete set of certification procedures for pharmaceutical products to ensure the safety and effectiveness of new drugs. The general sequence is that pharmaceutical companies submit investigational new drug applications to FDA, and then FDA sends people to test new drugs. At this time, the new drug Human trials haven’t started—unless you’ve done secret and illegal experiments—the FDA mainly reviews in vitro safety data and animal experiment data to determine whether the drug is safe enough to enter human trials.”

"Human experiments are divided into four stages. The first stage mainly tests the safety, main side effects and metabolic mechanism of the drug. The number of experimental samples is generally less than 200. The second stage mainly tests the effectiveness of the drug to determine whether the drug can be effective. It acts on the human body; at the same time, the safety and side effects of the drug are also objects of close observation; at this stage, the number of experimental samples is generally less than 300 and greater than 200."

"If the second phase of the experiment is encouraging, a larger sample will be tested, that is, the experiment will enter the third phase. The third phase will include different age groups, different populations, and different dosages to comprehensively study the safety of the drug. and effectiveness. The number of samples in the Phase III experiment ranges from a few hundred to a few thousand."

"The last four phases are mainly carried out after the new drug is approved, mainly testing the long-term safety of the drug and other information. When the pharmaceutical company completes the human experiment and verifies the safety and effectiveness of the new drug, it will officially submit NDA to the FDA, that is, the new drug Apply."

"At this time, the FDA will review all animal and human experiment data, as well as drug metabolism mechanism data and production GMP data. If the data is incomplete or unreasonable, it will review it. Under normal circumstances, the entire process will It lasts for about ten months, giving consent or rejecting opinions.”

"so……"

When Alice finished her long speech again and took a sip of the mineral water in her purse, Sissy, with a tangled and pained expression on her face, said in a long voice, "Just from that investigational new drug review request?" Counting from the beginning, the whole process will take at least...how long? Two years? Or three years? How long does it take!? "

"This is the medical industry, and you can't be too cautious."

Maiya said calmly: "That's why, only large companies with abundant capital can set foot in this industry, and these current pharmaceutical factories are all super giants with operations all over the world. It is a system that has just emerged, and these pharmaceutical factories often have a history of hundreds of years, but after so many years, if you say that they have not been deeply rooted in the political circle, you yourself will not believe it?"

"So complicated, so complicated, so complicated!"

Ashley also had a dizzy expression on her face, and her yelling at the top of her voice made a passing boy who also went to bed late at night keep looking sideways, but no one paid attention to whether he had hit a telephone pole.

"Alice, hurry up and work hard to save money! Anyway, Professor Delof won't achieve anything in a short period of time, so you should quickly make more money by investing in Japan. Since it takes several years to complete the approval of new drugs, if we If it can’t be mass-produced as soon as it comes up, wouldn’t it be a loss!?”

"The order of front and back seems to be a bit problematic, but the basic idea is not a problem..."

Alice giggled and stood where she was. At this moment, everyone has almost reached the door of the dormitory building, but the topic being discussed now is not something that can be chatted in the dormitory. At this time, standing in the middle school dormitory area under the night, Alice also suppressed her voice.

"My batch of investments in Japan will be hundreds of millions of dollars in cash as soon as I get it, but it will take at least one or two years to bring benefits. Professor Delof's research also takes time, new drugs and so on, we are only now It's just a sign. So during this blank period..."

She rubbed her chin, looked at the girls' apartment building in front of her, and said thoughtfully: "Well, none of our classmates have fuel-efficient lamps. People are floating in the rivers and lakes, how can they not have any connections?"