The Godfather of Surgery
Chapter 1036 System Vacation
Huang Jiacai reported a lot, but Yang Ping didn't really listen. His mind was not on these things, but on his own research.
Anyway, Yang Ping was assured of Huang Jiacai's work. After he finished his report, Yang Ping just nodded symbolically.
After Huang Jiacai left, Yang Ping began to think about his own research topic again. Brian has made great achievements in immunology. In the field of immunology, some of Brian's laboratory methods are absolutely the most advanced in the world. Yang Ping has communicated with him intentionally or unintentionally during this period, and has learned a lot of knowledge in immunology. This knowledge is very meaningful to his scientific research. Some of it can even directly replace the original laboratory methods and improve the efficiency of the experiment.
Yang Ping's current research on tumors will definitely apply knowledge in immunology, because the M13 phage must not provoke the immune system after being modified, otherwise all previous efforts will be wasted, and when marking tumor cells, a lot of knowledge in immunology is also involved, such as knowledge of antigens. Research on tumor treatment cannot avoid immunology. Now that there is such a big cow here, Yang Ping will definitely squeeze his knowledge hard.
The transformation of the M13 phage includes several parts. The K factor is transplanted onto the M13 phage, and then a molecule that can be paired with a certain marker substance on the surface of the tumor cell is found, and the pair of molecules is used for positioning, identification and coupling. Equivalent to the navigation of a missile, the modified M13 phage must also have its own navigation system to identify and connect to the tumor system.
The whole process is very complicated and involves knowledge of targeted therapy, but these difficulties are not difficult for Yang Ping. Not to mention the system, even if there is no system, Yang Ping will face the challenge.
Yang Ping took this time to enter the system and prepare for the experiment, but after entering, there was everything in the system space, empty. What's going on? Why is there only a pure space? The previous system panel, equipment, and experimental subjects are all gone.
When Yang Ping was wondering, a series of words appeared in the air: the system entered a dormant period, and the dormant time is unlimited to test the real knowledge and skills mastered by the host.
What's going on?
Yang Ping had read a lot of online novels before. Although he was not very knowledgeable, he knew a thing or two. He had never heard of the system going on strike, and it was called a test to see whether the host had learned real knowledge and skills by using the system.
Is this a test for the time when he was implanted in the system? To see if he had made good use of the system?
"The countdown for the system space contraction begins, 10-9-8-"
Before Yang Ping could react, the system space began to contract, getting smaller and smaller, until it was completely contracted into a point, and Yang Ping was forced to come out of the system space.
Damn, the system still did this, which meant that now he had no system to use, and he didn't know how long this would last. Fortunately, he was still diligent. Since he had the system, he had been immersed in the system almost day and night, reading all the books in it many times, and using all the functions of the system that should be used. He was almost always squeezing the value of the system. I don't know if it was overdeveloped, which made the system overwhelmed. Now he needs to take a break.
Although the system's dormancy was somewhat unexpected, Yang Ping was not too sad, because from the first day he got the system, he had already made plans for the system's departure, so the system's temporary vacation did not have much impact on him, at least not psychologically. He had always regarded the system as a tool and did not absolutely rely on it.
Although there was no system available for the time being, Yang Ping's work was still going on normally.
He first started to study the transformation plan of the M13 bacteriophage with paper and pen in his office. He drew an image of the M13 bacteriophage, then expressed its structure clearly and marked all the parts that could be disassembled and assembled biologically. Then facing this picture, Yang Ping thought about where to assemble the K factor and the navigation factor.
Yang Ping found that the training in the system during this period of time has made him very powerful in terms of thinking, memory and concentration. In fact, the system space not only allows him to learn knowledge, but also allows him to hone his abilities. He tried several solutions to assemble the K factor and the navigation factor on the M13 bacteriophage.
This step is not difficult for Yang Ping. K factor, that is, tumor killing factor, is already available, and the effect of in vitro experiments is very good. However, there is no suitable substance for navigation factor at present, which is the difficulty this time.
In order to make this missile accurately attack tumor cells, Yang Ping needs to obtain a lot of information about the target of tumor cells. Lu Xiaolu has been studying this topic in the laboratory and has collected some information in this regard.
After finding out the target of tumor cells, then contact the target to study the navigation factor, because they are a pair that must interact. The navigation factor must rely on the target to identify tumor cells. Once the recognition is completed, the M13 phage combines with the tumor cell, injects the K factor into the tumor cell, starts the apoptosis program of the tumor cell, and completes the hunting of tumor cells.
Without the trial and error opportunity of the system space, Yang Ping can only start to conduct in-depth research on the target by himself, hoping to summarize a set of theories to screen the target, which can save a lot of time and reduce the number of trial and error.
Yang Ping is used to closing his eyes and resting his mind. He closed his eyes and leaned back on the chair, immersed in his own thinking, and gave full play to his wild imagination.
How to make the modified M13 phage find tumor cells? Different tumor cells have both similarities and obvious differences. Therefore, the future M13 phage should be personalized for different tumor cells to make it have affinity for one or a class of tumor cells.
Just like the hepatitis B virus has strong selectivity for stem cells, how can the modified M13 phage recognize the current experimental tumor cells - Sisi's tumor cells.
Someone knocked on the door, and Yang Ping came back to his senses from thinking: "Come in!"
It was Song Zimo who came in: "I heard that Mr. Zhang has severe body aches. Do you want to go see him?"
"Are the symptoms serious?" Yang Ping was worried.
Song Zimo said: "It should be quite serious. I heard that he can't hold on. Just now, Fatty Liang, Zhang Lin, Xiaowu and several others went to Mr. Zhang's house. They were in a hurry when they went."
"How did these guys go to see Mr. Zhang alone without telling us?" Song Zimo felt strange.
''Yes, why don't I have any news at all. "Yang Ping looked at his cell phone, it still had power.
Outside the door, a graduate student was walking hurriedly with a bag on his back, and Song Zimo stopped him: "Where are you going?"
"I'm going to Mr. Zhang's house?" the graduate student said.
"What's wrong with Mr. Zhang? I heard Zhang Lin on the phone say he couldn't hold on any longer, what's going on?" Song Zimo asked.
The graduate student immediately said: "Oh, he hasn't played the game of PUBG for several days, he couldn't hold on any longer, so he asked a few buddies to go to his house to play a big game together today-——"
Yang Ping and Song Zimo were immediately confused.
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