The Godfather of Surgery

According to Sisi's current condition, it is unlikely that she can go to school normally. Yang Ping had a long talk with Sisi's parents, hoping that Sisi can temporarily take a leave of absence for hospitalization.

Although a suitable treatment plan has not yet been found, hospitalization can provide symptomatic treatment, monitor the development of the disease, and provide timely rescue when life is in danger.

In terms of medical treatment plans, it can be divided into causal treatment and symptomatic treatment. Causal treatment is treatment for the cause of the disease, and symptomatic treatment is treatment for the symptoms. It can be simply understood as the difference between treating the root cause and treating the symptoms.

Unfortunately, at present, most of our treatment plans for diseases are symptomatic treatment, and only a very small number of diseases are causal treatment.

That is, most diseases cannot be cured, only a very small number of diseases can be cured, and those diseases that seem to be cured actually rely on the body's own immunity to recover, and medicine is only an auxiliary.

The most successful causal treatment is bacterial infection treatment. Before the emergence of penicillin, the mortality rate of bacterial infection was astonishing, and any infectious disease could kill people. Since the emergence of antibiotics such as penicillin, bacterial infectious diseases can be said to have been conquered by humans.

Antibiotics are used to treat pathogenic bacteria and eliminate them, so after the bacteria are eliminated, the disease will naturally recover.

Therefore, there are only a few diseases that can be cured, and there are a lot of diseases that can be cured. The most common disease for humans is acute upper respiratory tract infection, which we commonly call "cold". The most common cold is a viral infection. At present, except for a very small number of viruses, there are effective antiviral drugs, and most viruses have no effective antiviral drugs.

In fact, all the drugs and methods for treating colds in our modern medicine are to relieve the symptoms caused by the disease, and cannot change the course of the disease itself. It just makes the patient feel more comfortable during the illness, and the recovery of colds depends entirely on the body's own immune ability, which has nothing to do with the treatment of cold medicine. Even many drugs only play a psychological comfort role and have no real effect.

For example, hypertension, diabetes, etc., are all symptomatic treatments, using drugs to control blood pressure and blood sugar, but they cannot eliminate the causes of abnormal blood pressure and blood sugar. Even why blood pressure and blood sugar are abnormal, the mechanism is not very clear at present.

Professor Zhang Zongshun admitted Sisi to the hospital for the first time, so Professor Zhang has always been concerned about her condition and came to talk to Yang Ping from time to time to understand her situation. Professor Zhang heard that Sisi's condition had worsened, the tumor had metastasized throughout the body, and metastases were found in the brain stem, and they were diffusely growing, so Professor Zhang was very worried about Sisi.

Professor Zhang is already in his eighties, and it can be said that he has seen through many things and has long passed the age of being happy and sad about things.

In Yang Ping's office, he stared at Sisi's MRI images for a long time, and after thinking for a long time, he said: "It can't be removed now?"

"No, tumors on the lungs, liver, and peritoneum can be removed, but it is meaningless to only remove tumors in these parts. It is purely for surgery. The metastasis in the brain is the key. If the brain cannot be treated, it is meaningless to only treat other parts. It is just a waste of surgery, which is counterproductive." Yang Ping always speaks directly to Professor Zhang.

"The tumor in this area is difficult to deal with. What will happen if it continues to develop?" Professor Zhang knew the consequences, but he still asked one more question.

Yang Ping pointed to the intracranial tumor on the image with a pencil and said: "Whether it is a ruptured and bleeding tumor, impending compression, or damage to brain cells, once it breaks through the critical point, the consequence is respiratory and heartbeat arrest, and there is no way to rescue it."

"It's difficult!"

"So I keep her in the hospital now. If this child is not in the hospital, she may die one day."

"We went around in circles, but we didn't get around it after all."

"Yes."

"Are there any new drugs in the field of targeted therapy for this type of tumor? Internationally?"

Professor Zhang is an old expert in orthopedics and has a certain reserve of knowledge about tumors. He also keeps reading the latest literature every day, but his grasp of the latest knowledge is definitely not as good as that of young people.

Targeted therapy drugs are actually developing well now. Some tumors can be controlled by targeted therapy alone, and a few tumors can be cured by targeted therapy.

Yang Ping shook his head: "There is no effective targeted drug for this tumor. There are several clinically used targeted drugs with poor therapeutic effects, but it is better than nothing."

"What about CAR-T cell therapy? Is there any progress in this regard?" Professor Zhang was very persistent and had to ask to the end.

CAR-T cell therapy, which costs 1.2 million per injection, can cure non-Hodgkin's lymphoma and completely eliminate tumor cells. This effect can be described as amazing in tumor treatment.

"The excellent effect of CAR-T cell therapy only stays in the treatment of non-Hodgkin's lymphoma. There is no effective treatment for other tumors." Yang Ping denied it again.

"Immunotherapy? Biological therapy? Isn't there a feasible solution?" Professor Zhang raised his voice.

Yang Ping still shook his head. If there was a way, he would not have sat here and talked with him for so long, and went straight to the topic.

Professor Zhang did not speak again. He just quietly looked at the MRI picture on the electronic screen, squinting his eyes.

In his decades of medical practice, he has encountered such helpless situations countless times. This is not the first time, and it will not be the last time.

"Try your best, try your best to improve the quality of life, and let the child die with less pain. This can be done."

Professor Zhang stood up, stretched his waist, and then walked out of the doctor's office with his hands behind his back. Yang Ping watched his back, and felt a little uncomfortable.

In fact, every doctor wants to cure his patients, but often they can't do it.

After walking a few steps, Professor Zhang turned his head and looked into the doctor's office, and saw Zhang Lin instructing the interns on how to write good medical records.

"Xiao Zhang, gather everyone and come to the duty room to work overtime!" Professor Zhang shouted.

Zhang Lin is busy now, and he hasn't finished explaining the medical records to the interns, so he replied: "Today is busy, how about tomorrow."

"What are you busy with? Hurry up, pull the team over, and let's have a good time today." Professor Zhang said in an unquestionable tone.

Zhang Lin immediately put down what he was doing and started calling people on his phone. What happened to the old man today? Why did he seem a little angry and talk wrong?

Sisi herself was very relaxed. She didn't care what her condition would become, so Yang Ping didn't explain her condition to her this time. She didn't ask, nor did she ask her parents about her condition. Maybe she had gotten used to these things because of the repeated changes.

At this time, Yang Ping couldn't help but think of Luo Jin, who is now playing football in Europe. He heard that he could only save his life and couldn't play football after the operation. He gave up the operation and would rather spend the remaining time on the green field than have the operation.

Luo Jin has experienced too many hardships since he was a child. Perhaps he has seen the true meaning of life, and his thoughts are different from those of ordinary people.

From some of the examination images sent back by Luo Jin, it seems that he doesn't have much time left, but he doesn't care.

Sisi's mood is the same now. This time, she is calm and calm, without any anxiety or impatience, as if nothing has happened.

——

When Yang Ping was worried, Professor He brought good news. The AI ​​primary simple model designed by their team for the laboratory was ready for use.

This model is just a small and lightweight model, and they are also preparing to develop a large AI model.

Before the large model is developed, the laboratory of Sanbo Hospital can temporarily use this small model for transition.

This is good news. Yang Ping decided to use this AI model to screen and transform the virus immediately. If it relies on manpower to screen and transform, it will take at least several years to find a suitable virus carrier. Now with the assistance of AI models, this time can be greatly shortened.

Even if Professor He has only launched a rough and simple model, it is thousands of times stronger than manpower.

In the past, because of the assistance of system space, Yang Ping could put the entire test screening process in the system space, which can greatly save time. Now that the system space is temporarily on strike, Yang Ping can only think of a way by himself. The best way is to use computers, especially AI.

However, AI models cannot be developed just by development. It takes a certain amount of time to accumulate technology.

However, money makes things easier. In order to develop this artificial intelligence model, Ruixing Group has spent a huge amount of money to acquire several excellent start-ups in the world, which can save time and is much better than starting from scratch.

As Yang Ping's partner, Professor He can share the technologies acquired by Ruixing Group. Professor He's current team uses the acquired technologies to reorganize and improve, and soon made an artificial intelligence model that can be used immediately.

Later, they will learn from each other's strengths and weaknesses, integrate these models, and then build their own new large model.

After hearing the news, Lu Xiaolu immediately took people to Professor He's Digital Medicine Laboratory at Nandu Medical University to use their models to screen and transform viruses.

In about two hours, it proposed hundreds of thousands of solutions for virus screening and transformation, and then sorted these solutions, and finally selected more than a dozen optimal solutions.

Yang Ping decided to immediately carry out laboratory cultivation after the virus screening and transformation was completed.

Yang Ping will use these cultivated special viruses directly on Sisi.

This is indeed too risky and unethical, but he has no better way, he must race against time.

When virologist Beata Harasi used oncolytic virus therapy to treat her own triple-negative breast cancer, she used her own body for the experiment. In history, many scientists have used their own bodies for experiments, which can save experimental time.

But Sisi is different. Once the clinical experiment is conducted directly on her, she and her family will definitely agree and will fully cooperate.

But society will definitely not agree. Yang Ping will face ethical torture, social doubts, and public opinion storms in the future.

Once it fails, if Sisi dies, he is likely to fall into the ethical condemnation of the whole society and eventually lose his reputation. In most cases, the torrent of social condemnation is not rational at all, let alone in-depth thinking.

Who cares, how much is reputation worth? Compared with human life, reputation is nothing!

Yang Ping sat in his office thinking about this. When he was still an ordinary young doctor, although he worked hard, he would not have achieved what he has today without the help of the system. He went through so much learning and training, wasn't it to cure diseases and save lives? If he was timid for his own reputation, he didn't deserve to have this system.

He couldn't care less. He needed speed. Sisi didn't have time to wait.

When Yang Ping proposed to use the special virus directly on Sisi, Dean Xia, Director Han, Song Zimo, Xu Zhiliang, etc., all looked at him in surprise.

"This is a brand new special virus. You used it directly on the human body without any ethical review. If it caused Sisi's death, the public opinion consequences would be very serious. You have to think clearly!" Dean Xia said.

"I have thought it through. I must do this." Yang Ping said firmly.

Dean Xia paced back and forth in the office. If this matter went wrong, social public opinion would be overwhelming. If it was used by certain forces, it would be like a flood.

Yang Ping would definitely be ruined by then!

"Do you want to consider it? Are there any other ways?"

"I have thought it through. There is no other way."

"Do you have to do this?"

"Definitely!"

"Okay, I will be the first to support you. If you are not afraid, why should I be afraid? I have been the dean for so many years and have never done anything crazy. Now I will accompany you. I will hold a meeting on this matter. If something goes wrong, I, Xia Changjiang, will take responsibility."

For this reason, Yang Ping called everyone together and began to implement his plan.

The virus transformation model demonstrated with 3D animation was suspended on the electronic screen. The K factor was embedded in the virus to form a complex protein structure. This is a brand new virus.

This is a magical virus that has been virtualized in the virtual environment of Professor He's digital medical laboratory. It can carry the K factor, reach the tumor through the blood circulation, and then infect those tumor cells, and then start the apoptosis program of the tumor cells. Finally, the tumor cells die, and normal cells are not affected at all.

According to normal procedures, the ethical approval of this experiment is extremely strict. After the sample is manufactured, the next step should be animal experiments. After the animal experiments are qualified, they can enter clinical trials after passing various approvals.

Yang Ping calculated that the whole process would take about 5-10 years. How could Sisi have ten years to wait? It was unknown whether she could survive tomorrow.

Now, regardless of whether this plan would work or not, it was the only possible method, and he could only try his best to save her.