The Godfather of Surgery

Yang Ping's choice of stem cells to cultivate muscle was not a whim, but a deliberate one.

If successful, it will be easier to overproduce other organs in the future, such as skin, tendons, ligaments, cartilage, bone, and even joints.

In the long run, it can also develop towards cultivating the heart, liver, kidney, etc.

This subject organization technology and equipment will be relatively convenient, such as nano-micro-scaffolds, which are relatively easy to obtain through Takahashi.

Nano-micro-scaffolds have very high requirements for 3D printing technology, and their three-dimensional structure arrangement is at the level of cell clusters, which must be able to guide muscle fibers to perform spatial configuration.

This level of 3D printing technology is currently not available in China, and the core technology is monopolized by German and Japanese companies.

This is also the reason why Yang Ping seeks international cooperation. It is impossible for one person to break through all industrial technologies, and he can only work hard in medical technology.

The obstacle that the United States and Japan cannot overcome now is the collapse of cells. The collapse stems from the instability of certain cell structures. There are many unstable factors, such as unstable cell membranes and unstable organelles.

Many papers now assume that everything is said, these collapse factors, any one of which acts as a trigger, causes the cell to collapse, causing other structures to collapse. When researchers are observing, it is not surprising that they focus on one side for various reasons.

This is the inevitable result of artificially induced stem cell differentiation. In the case of immature induction technology, it will inevitably cause some structural instability, which is the potential cause of collapse.

In fact, stem cells are in full swing in organ cultivation.

The University of Tokyo also cultivated the world's first heart, 1 mm in diameter, with complete ventricular and atrial vascular structures, about the size of a mouse fetal heart.

The same is the National Center for Adult Medicine in Japan to cultivate the liver; the University of Edinburgh in the United Kingdom cultivated the kidney; Harvard University in the United States cultivated the skin.

These technologies all face a common problem - maturity and stability.

If this problem is solved, these technologies can move from the laboratory to the clinic.

Muscle cultures are by far the most mature and can be transplanted into animals for weeks of survival.

Those internal organs, such as the heart, are small hearts with a diameter of only one millimeter. If they are cultivated further up, they will face the problem of collapse and cannot allow the small hearts to grow up smoothly.

Yang Ping wants to start with muscles and solve the problems of maturity and stability.

It is then extended to skin, tendons, cartilage, etc., which are widely used in orthopaedics.

With the skin, there is no need to dismantle the east wall to make up the west wall and make skin grafts or skin flaps.

With tendons, those patients who have ligament reconstructions have better surgical outcomes.

With cartilage, cartilage degenerative diseases, such as senile knee osteoarthritis, can be solved.

Even grow a joint for joint replacement.

Stem cells are the most promising field of surgery in the future, and it will change the history of surgery.

Maybe one day, a patient like Yu Shuilian can grow a complete lower body with her own cells, and then perform a transplant operation to connect the upper and lower bodies to restore a complete body.

After get off work in the afternoon, the young doctors from the Department of General Orthopedics, whenever they are free, go to Mr. Guo's dinner.

Mr. Guo was generous and set up several tables in the Hakka restaurant next to the hospital. He was so happy that he was willing to bleed so much.

After eating and resting for a while, Xiao Su said that Fujiwara Miyuki asked her to play ball with her and asked Yang Ping to go with her.

They seem to have made an appointment a long time ago, with tennis suits under their jackets, and racket backpacks.

Xiao Su is usually in the comprehensive orthopaedic operating room, and only interacts with Meixue during the operation. I didn't expect them to chat very well, and Tang Fei, the three of them are like old friends.

Everyone rests for half an hour, and then goes to the stadium, etc., and can almost do vigorous exercise.

Song Zimo, Tang Fei and Xu Zhiliang went back to the department, the fat man went for a run, Xiao Wu wanted to go home to accompany his wife, Zhang Lin's wife was on duty, he made a few bags, all of which his wife liked to eat, he had to deliver them in time.

Yang Ping, Takahashi, Xiao Su, and Miyuki went to play tennis, but Yang Ping and Takahashi did not change their clothes.

Xiao Su pulled Yang Ping: "Me and Miyue have a good fight, you just need to be the audience."

Miyuki held Xiao Su's hand again: "China-Japan women's tennis friendly match."

Takahashi felt as if he had become redundant, so he followed behind, keeping a certain distance.

However, watching two tall beauties play tennis is actually quite eye-catching.

The two of them even booked the venue for the hospital gymnasium in advance. Yang Ping and Takahashi simply sat down beside them and discussed the cooperation on the subject.

The two stunning beauties were playing tennis, attracting a lot of attention from the side, and people looked at them from time to time.

The two of them are very good, very fierce, the game is tied, and the score is very tight. It seems that Xiao Su has met an evenly matched opponent.

Takahashi took the initiative to propose: "Dr. Yang, premature cell collapse is a problem faced by all stem cell culture organs at present. If it can be solved, it will be an epoch-making progress. If Dr. Yang decides to set up this project, Takahashi asks for cooperation, and the University of Tokyo's For the research group, I am the main person in charge and have enough say."

"Cooperation can save us a lot of time. I don't want to repeat the wheel, I just want to tackle the most critical difficulties." Yang Ping stated his plan.

"If Dr. Yang is willing to cooperate with us, we can share all the previous technologies, which will save Dr. Yang's time, and we will be win-win." Takahashi also thought so.

At present, the University of Tokyo is at the forefront of this technology, but it has encountered difficulties. Yang Ping analyzed all the current papers.

It was found that recent papers from the University of Tokyo all focus on the survival period of cells implanted in animals, and the increase in time, one day, two days, is very slow.

This shows that they have no technological breakthroughs for the time being, but only continuously improve the original technology.

Working with them will get twice the result with half the effort.

Scientific research is similar to sailing. The development of a new route requires countless trials and errors, constant corrections, and accumulation of data.

If you obtain the artifact of the system space laboratory in the future, you will also need a real laboratory to complete the test.

The data obtained in the system space laboratory can make oneself take less detours in reality, and even achieve it in one step, but the entire experiment needs to be repeated in the laboratory in reality.

So, there is no harm in cooperating with these top international universities or hospitals.

The key is how to use and control these resources, and be the leader among them. While insisting on self-renewing scientific research, we must also open up cooperation, Yang Ping thought.

Takahashi has seen Yang Ping's surgical technique and thinking ability with his own eyes, and is convinced of Yang Ping's ability.

Now I have established a friendship with Yang Ping because of my advanced studies, so I have the honor to cooperate with him.

In the future, when Yang Ping's scientific research becomes popular, it is estimated that the team cooperating with Yang Ping will have to queue up, and it will be even more difficult for Gaoqiao to squeeze in.

Yang Ping pondered while watching the beauties play: "Takahashi, let's cooperate and share the results."

"No problem, I will send an official email to contact the University of Tokyo in the evening to obtain authorization to negotiate and sign the contract. We will definitely not be worse than Duke University. Although we cultivated muscles with stem cells later than them, we also completed it independently. , but the paper was published a little later, compared to them, we are more advanced in induction technology and micro-scaffolding, their animal survival time is three weeks, ours is six weeks."

Since Gaoqiao knew Yang Ping, he has seen Yang Ping create miracles constantly. He firmly believes that if Yang Ping focuses on the field of stem cells, he will definitely be able to create miracles.

Selfishly, Gao Qiao wanted to get on this boat. As for the conditions of the laboratory, the existing technology may be very precious to others, but for a person like Yang Ping, even if you don't talk to him With cooperation, he himself can catch up, just a little longer.

If he proposed cooperation at that time, it is estimated that Yang Ping had no interest at all. Now that he proposed cooperation, at least he could use the existing technology to help him save time.

After a few rounds, the two beauties were drinking water, chatting and laughing across the net.

After five rounds, Xiao Su was still stronger, winning three rounds.

Everyone packed up, Xiao Su and Meixue went back to the dormitory to take a shower and change their clothes, Yang Ping and Gao Qiao went to occupy a seat, and a few people wanted to find a barbecue stall for supper.

Yang Ping also called out Song Zimo, Xu Zhiliang, Zhang Lin, Xiaowu, and Fatty.

Zhang Lin is still in the pediatrics department and accompanies his wife on night shifts. Xiao Wu's home is near the hospital, and the two will be there soon.

Song Zimo and Xu Zhiliang were peeling grapes under the microscope, and they came out without hesitation when they heard that there was a late-night snack.

Everyone gathered around, Zhang Lin asked for a few cases of beer, except Yang Ping and Song Zimo who didn't drink it, all the other men drank it.

Several big men kept their mouths open and continued the topic of the topic just now. Song Zimo and Xu Zhiliang also joined.

The three girls were chatting together. Fujiwara Miyuki was very good at Chinese. From time to time, she used interesting Internet terms, which made everyone laugh.

Takahashi drinks very refreshingly. As soon as he touches the glass, he immediately kills it. In strict accordance with Teacher Tang's instructions, no matter who he clinks with, the glass must be lowered by one centimeter.

"Go to Japan, I'll treat you to Wakayama's Seaside Beer!"

Takahashi thinks that these Chinese friends are very good. He wants to learn from Abe Nakamaro and write an article on this training. The best book is to let the Japanese also gain insight.

Those girls didn't know what they were talking about, they were so happy, they seemed to be talking about interesting places in China, and Meixue had found a good sister in China.

They don't care what the men here are talking about. They are clinking a few glasses of juice. They are going to go horseback riding on the grasslands of Inner Mongolia, go to Tibet to see the snow-capped mountains, and go to Hangzhou West Lake to wear Hanfu to take pictures.

It's fucking cool to have a skewer with beer!

Gaoqiao, Xu Zhiliang, Zhang Lin, Xiaowu, Fatty, you have a cup, I have a cup, plus two vinegar drinkers, the atmosphere is very warm.

"Xiao Gao, let's do it, let's do it!" Zhang Lin filled Gao Qiao immediately.

"Do it first as a respect!" Takahashi didn't hesitate, flipped the cup over, it was dry, and he would not refuse anyone who came.

After drinking, Takahashi got up and pointed to the direction of the bathroom: "Old irons! Wait for me, relax, come back and continue the fight."

Who taught him this, the old iron called it?

Zhang Lin, Xiao Wu and Fatty were stunned for a while, this kid.