Rebirth of the God-level Xueba

Intense and continuous scientific research competitions do not actually exist. It seems that no matter how strong the troops are, they cannot continue to participate in siege battles. They must be given a chance to recuperate.

The same is true for laboratories participating in the world's top scientific research competitions. Although high-level laboratories have multiple groups, they can rotate, but make slight adjustments between competitions, or slow down slightly when they occupy the leading position. Take it easy, it's normal.

Of course, the most common rest mode belongs to a slightly backward laboratory. There is usually only one winner in a scientific research competition. Therefore, laboratories that have fallen behind a lot, when there is no hope of pursuing them, will often make groundbreaking experiments into repetitive experiments, thereby reducing costs, temporarily doing self-cultivation, and waiting for the next battle.

However, the risk of doing so is also obvious. If you lag behind in autonomy, you will reduce competition, and the initiative of the competition will be in the hands of other laboratories.

If the leading laboratories postpone the release of information and publish papers, then they may lose the second round of the scientific research competition without knowing it, or even the third round or the fourth round. Such things have not happened Pass.

This is exactly what Yang Rui hopes to do.

Nowadays, the scientific research competition on g-protein coupled proteins is in the ascendant, and all laboratories are still warming up. Yang Rui does not want to startle the snake.

Now is also the time when the ion channel laboratory has the only advantage.

If those well-known laboratories actually have a certain understanding of each other, it is not so easy to postpone the release of information or to postpone the publication of papers. At the very least, the other party can guess your progress. In addition, you can also Get informed by the instruments and equipment you buy.

The most direct information comes from the funder, whether it is a government-invested project, a company consortium, a foundation, or even an individual-funded project, it is always necessary to publish some information, especially in developed countries, there are considerable systems to ensure this. point.

In this way, there are traces to start projects that exceed the original project schedule requirements, whether it is additional funds or the use of remaining funds.

However, these usually belong to foreign labs, belong to first-class laboratories in developed countries, not third world labs.

Even if the ion channel laboratory has to report any information to the research management department, foreign laboratories do not care.

To this day, no "foreign friends" know that Yang Rui is going to release the G-protein coupled receptor as a big satellite.

Moreover,

Satellites are not something you can release if you want. Before proving himself, Yang Rui deliberately ran to release satellites, and it might not have any effect.

However, the researchers in the ion channel laboratory did not have the slightest doubt.

At least in the domestic environment, Yang Rui is the most qualified candidate to be a GPCR.

And if it is said that no one in China can make g-protein coupled receptors, no one is willing to listen to it, and no one believes it.

In order to prove similar negative propositions, the Chinese people do not know how much effort and sweat they have put in.

In the spring of 1986, the researchers of the ion channel laboratory once again felt a sense of urgent mission.

"Put the lid on the centrifuge."

"The 50ml test tube doesn't have weights? Don't you want to kill yourself? Do you know how powerful this thing is when it is thrown?"

"These are ultracentrifuges. If you slam a test tube out, it can smash through the wall and kill the two people next door."

Su Xiankai walked in small steps in the laboratory, tirelessly checking every step.

The first step in G protein-coupled receptors is the production of large amounts of the bovine rhodopsin protein. The production and large quantities here are relative to the normal laboratory scale, but in terms of steps, it is not much less than the factory.

The most troublesome part here is that the production of bovine rhodopsin protein requires a low-temperature ultracentrifuge before it can be used.

As for the low-temperature ultracentrifuge... Before Yang Rui's ion channel laboratory purchased it, there was only one in Peking University.

As for now, in order to make G protein-coupled receptors, Yang Rui bought 6 sets at one go, and the price of each set exceeded 80,000 US dollars. The most expensive one was 150,000 US dollars, which was more than the net worth of many laboratories.

If it is not your own money, or the Ion Channel Laboratory’s own funds, Peking University will not necessarily approve it, not to mention forced organization, forced talks and delays are all possible. The value of the existence of superior leaders lies in the fact that your three views are not in harmony. When the time comes, use force to suppress you.

But a cryogenic ultracentrifuge is indeed needed.

Bovine rhodopsin protein is used for comparative research, it is equivalent to the basic resource of the whole experiment, the more quantity the better.

Without a large amount of bovine rhodopsin protein, it is impossible to talk about Yang Rui's current project.

In fact, it was because foreign laboratories had discovered the connection between bovine rhodopsin and g protein-coupled receptors that Yang Rui decided to carry out this project.

This makes bovine rhodopsin protein a basic material, and the more the better, the basic material will be consumed as much as you make. Unfortunately, the processing of bovine rhodopsin protein is not a basic processing...

Su Xiankai's initial task was to understand the bovine rhodopsin protein and produce as much of it as possible as quickly as possible.

This is boring but necessary work.

A bit like the production of uranium during the development of the atomic bomb.

Both research and production of atomic bombs require a large amount of uranium. It is not a problem to say that atomic bombs are based on the production of uranium. The heavy water reactors that are often mentioned in the North Korean nuclear issue refer to uranium production equipment.

However, the important thing is that this job is not easy.

Unlike standardized factory production, Su Xiankai needs to constantly adjust the parameters of various reagents, and even experimental methods, just like doing real exams for the college entrance examination every day, keep doing it, keep doing it, and try his best That gets high marks.

He seems to be doing similar problems forever, but he always makes unexpected mistakes, which makes Su Xiankai very anxious.

"How's it going?" Yang Rui has been showing great concern for Su Xiankai's work in recent days.

Su Xiankai knew why, shook his head lightly, and said: "I still need a while, the concentration of the solution is too low recently, I want to increase it a little bit, and then increase the speed of the centrifuge, and shorten the time..."

"It's been a while." Yang Rui patted Su Xiankai on the shoulder and said, "Let's start sending materials to Fan Zhenlong's group today."

"No, how can I do it!" Su Xiankai quickly shook his head, and said: "We have very little stock now. Fan Zhenlong just started to make mistakes. It is a waste of time for materials. Wait for me to improve and accumulate more. stock……"

"Old Su." Yang Rui shook his head and said, "Scientific research competition is a battlefield, and it is never possible to be fully prepared."

"I..." Su Xiankai opened his mouth and said, "What if the back is broken?"

"I believe in you." Yang Rui gave such a sentence.

Because, to be honest, Yang Rui doesn't know how to increase the amount of bovine rhodopsin protein that meets the requirements.

He has a way to point out the direction, but what Su Xiankai needs now is not the direction, but the specific experimental values, not even the numerical values, but the accumulated experience from more experiments.

This is something that Yang Rui can't give. What you give him is only requirements and funds.

Su Xiankai's eyes turned red, he looked sideways at Fan Zhenlong, and said, "You better not waste my hard work, kid."

"I will try my best." Fan Zhenlong's honest answer made people's teeth itch.

...