Rebirth of the God-level Xueba

Chapter 1271 Drug Effects

Yang Rui arrived at Astra's office area half an hour earlier, and sat quietly in the lounge, reading his manuscript. ? Bayi Chinese??? W? W? W?. (A) 8? 1? ZW. COM

Giving lectures in a large company is very polarizing. Sometimes, certain professors will receive extra praise, and sometimes they will receive special ridicule.

With a good title, it's usually easier to get the former.

For example, a professor at Harvard University, a professor at Stanford University or a fellow of Trinity College in Cambridge, etc., are always more convincing, but not always.

A good example is a professor at Stanford University. Due to the distance, start-up companies in Silicon Valley often invite Stanford professors to give lectures, but those who go there may not necessarily be recognized by Silicon Valley people. Although many Silicon Valley people came from Stanford University's computer science department, they still ridiculed them very hard. After years or years of hard work, those well-paid Silicon Valley people are no longer what they look like in school, and they have their own understanding of the true strength of Stanford University professors.

At this time, the professors at Stanford University are not necessarily at the forefront of the industry.

Moreover, the so-called cutting-edge theories they put forward may not necessarily be recognized by the industry.

The founders of Cisco, Bosak and Reina, can be regarded as examples of the industry. They are masters in computer theory and have made first-class practices. The exhibition laid the initial foundation.

But after carefully examining the identities of the two, one can know that it was not easy for them to do all this. Bosak is the director of the Computer Center of the Stanford Department of Computer Science, and Sandy Lena is the director of the Computer Center of the Business School. In the era when Silicon Valley was underdeveloped, they were basically top-notch scholars in the theoretical field.

Giving lectures to Astra is also not an easy task.

For such a large pharmaceutical company, it cannot simply be regarded as the level of the industry. In a company of this level, there are also hidden dragons and crouching tigers.

Of course, the original researchers of pharmaceutical companies have no sense of existence in front of scholars like Yang Rui. They belong to the bottom of the chain of contempt for scientific research. Whether they are good students or poor students, whether they are undergraduates or doctoral students, they will enter the pharmaceutical industry after graduation. Companies will basically not make achievements at the frontier of science.

Even if there are some special cases, they are usually not scientists recognized by the mainstream.

The goal of pharmaceutical companies is to find compounds for known targets in the field of g protein-coupled receptors. The main work of scholars in pharmaceutical companies is after systematic research by frontier scientists.

Taking a certain target in the systematic research as the research object, it can be said that the researchers in the industry are not even the second-line scientists, but can only be called the third-line, the so-called achievement converters.

However, for a company like Astra, in addition to the researchers from the original pharmaceutical company, there will inevitably be researchers transferred from the first and second tiers. Some powerful companies can even recruit Nobel Prize winners.

The 2oo8 Nobel Prize in Biology was awarded to Lald Howson, who was awarded for his research on the human neoplasia virus that causes cervical cancer. He has a close relationship with AstraZeneca, which can be regarded as one-third An AstraZeneca guy.

This time the Nobel Prize is also the most suspected Nobel Prize fraud case known to Yang Rui - although there is no conclusive evidence, AstraZeneca did play a key role in this Nobel Prize. One of AstraZeneca's directors is a Nobel Prize committee member, and before winning the award, he acquired a company that developed the key components of the hpV vaccine and will charge huge patent fees for this.

In addition, the chairman of the five-member committee responsible for selecting candidates for the Nobel Prize served as a fee-paying consultant for AstraZeneca in 2006, and one of the members of the fifty-member committee responsible for voting also took AstraZeneca in the name of a consultant Likon's money.

AstraZeneca also sponsored two institutions and promotional departments of the Nobel Prize Committee in the past few years. In addition, several members of the Nobel Prize Committee admitted that they were invited to travel to China at the expense of the Chinese side. Introduce to Chinese officials how the candidates are selected - that happened after 2005, which shows that China at that time already had a peeping heart for the Nobel Prize, or it was just that AstraZeneca took advantage of China's platform .

All in all, large pharmaceutical companies are like large military industrial enterprises or large energy enterprises, they are all organisms with huge energy, and their role in world affairs is stronger than that of most small governments in Asia, Africa and Latin America .

However, large pharmaceutical companies are also complex complexes of contradictions. They all have a history of tens or hundreds of years. The founder has gone, and the remaining professional managers and shareholders have difficulty finding a dominant player. Only one director or the chairman of the board can definitely decide on a major event.

Yang Rui needs to prove his strength even more, so that he can get a ride.

Before the Nobel Prize, everyone is equal, except Sweden.

"Mr. Yang Rui, it's time." Pulitzer came to the lounge and said in a peaceful voice.

Yang Rui stood up steadily, smiled, and asked, "Are there many people here?"

"There are about 60 people." Pulitzer said and explained: "Sweden is a country with a relatively small population. It is rare for a large number of people to gather at once like China."

Yang Rui froze for a moment, and couldn't help laughing.

Pulitzer knew that he had said the wrong thing, and couldn't help being a little embarrassed.

Yang Rui coughed and said, "The 6o people are very satisfying."

He is going to explain academic issues to the researchers, and there are quite a few people who can make up a class. To put it bluntly, there is probably not even 30 scholars who can understand what he is talking about at a symposium on g-protein coupled receptors being held in China, or even worse, maybe 15 reluctantly.

Although Wang Qi can be seen by looking up, it takes courage and luck to walk under Wang Qi with knee-high blood.

More than 60 people sat neatly in a classroom-like meeting room. Everyone had a chair, which was also neatly arranged.

It's really neat.

Standing on the podium, Yang Rui could see these chairs, like a military parade, with horizontal screens and vertical screens.

Moreover, unlike domestic lectures, everyone will deliberately sit a little farther away, or prefer to sit in the back.

The Swedes sit one by one from front to back, from left to right, and each chair is tensely next to each other.

The chairs are folding chairs, so there are no handles, which makes the large square chair array a little crowded, but everyone in Sweden sits upright, with their chests upright, neither making their positions different, And try not to have physical contact with other people.

If he didn't know that this was a temporary request, Yang Rui would have thought they had rehearsed.

Of course, it can also be said that they have been rehearsed. The Swedes have been managed collectively in this way since childhood.

In addition to the employees of Astra, several members of the Chinese delegation also came to attend the class, and there was only one row in total.

Yang Rui plans to teach in English, so if he doesn't understand, he won't use it.

In fact, you don’t have to come to listen if you can understand English. The content of Yang Rui’s lectures does not overlap with the research direction of most people.

"Today I want to talk about g-protein coupled receptors and g-protein." Yang Rui spread out the handout on the desk, without looking at it, he said: "I want to make a prediction first, in 30 years In the future, drugs targeting g protein-coupled receptors will account for 50% of the total number of modern drugs. In other words, when pharmaceutical companies develop new drugs in the future, at least one of every two new drugs will be based on g protein Coupled receptors are prescribed for the target..."

The Swedes, who were originally very quiet, suddenly became not so quiet.

As a very disciplined nation, the Swedes are very similar to the Japanese, and they both pay attention not to cause trouble to others. However, at this time, some people still couldn't help but shouted: "How is that possible."

This is not a question, and Yang Rui didn't have any desire to answer, but continued: "One of the two new drugs targets g protein-coupled receptors, which is actually not enough, because the 50% I said is 50% of the total number of modern drugs... But let’s not talk about the future today, let’s talk about the present, what can we do with g-protein coupled receptors now.”

After Yang Rui said this, everyone fell silent.

For researchers in pharmaceutical companies, "what can be done" is indeed dry goods.

At this time, Yang Rui seemed like a butcher. Pharmaceutical companies are in the business of catering. They need to understand how the pig is segmented and what is the most suitable part for each part?

In the end, whether the pork ribs are used for soup or sweet and sour, and whether the fat meat is used for oil refining or re-cooked also depends on the quality of the meat.

Of course, only pharmaceutical companies at the lower level of Astra are so particular about it. After that, it's normal to just pull a piece and do it.

Yang Rui looked down at his handout, and said again: "My ion channel laboratory has done in-depth research on g protein-coupled receptors, but the content of this aspect is not what I want to talk about today. I want to start from a new angle, and I named it the dynamic quality re-measurement method. This method is considered in my spare time. It is a small problem, but it is very useful. At present, the most appropriate place, lies in its ability to analyze drug effects on G protein-coupled receptors in primary human cells."

As soon as the word "drug effect" was uttered, the neat big squares immediately undulated left and right like waves.

That was the movement of the researchers whispering to each other.

...

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