Rebirth of the God-level Xueba

Neeson hunched over, found two pieces of toilet paper from his butt pocket, and then took out the pen that was always at hand, and wrote a few words on it with difficulty. Bayi??Chinese W?W?W. 81ZW. COM

"Drug Effects" and "Primary Cells" are written at the top by Nissen, followed by dynamic mass remeasurement.

Nissen originally had no plans to take notes today. He had worked in Astra Corporation for fifteen years. Before that, he was a visiting professor at several universities in Norway.

Because of his familiarity with the basic biology community, Nissen dismisses most biologists and will participate in today's lecture only because everyone else in the office has participated. As a Norwegian working in Sweden, Nissen does not want to appear to be a maverick, whatever the reason.

Now it seems that Neeson feels that he has come to the right place.

The only regret is that he did not bring a suitable notebook.

He looked to the left and right, and the people on both sides were carrying not-so-thin notebooks, and they were taking notes with their heads down. Their pens were fast and their handwriting was scribbled, but they almost wrote down everything Yang Rui said.

Neeson was a little envious.

He felt that everyone was lucky today. Yang Rui, who was born in China, obviously did not pay enough attention to his knowledge, so that he said such important things for no reason.

The drug effect of human cells is a topic that pharmaceutical companies desperately want to research.

How the drug changes in the human body, or the so-called pharmacokinetics, has killed many researchers.

Who would have thought that a Chinese scholar would actually research it in this way. Moreover, it turned out to be made during the spare time of working on g-protein coupled receptors.

Nissen believed Yang Rui's words. Those who can hold up the banner of g-protein coupled receptors can be said to be the top figures in biology. However, how can they easily conduct research on drug effects?

Neeson really wanted to say it was unbelievable, but hearing Yang Rui's open and detailed description, he didn't want to belittle the other party like this.

Any belittling, at this time, should not be in the hearts of researchers.

Neeson wrote two words on the toilet paper again, and looked at the handwriting in front of him, feeling a little annoyed.

He really didn't want to waste the opportunity in front of him.

"Hello, can you give me two pieces of paper?" Neeson asked with difficulty.

Asking for a favor is never easy for the Swedes, Norwegians and Danes.

On the other hand, helping others is an admirable quality. The researcher sitting next to Neeson tore off seven or eight pages from the notebook without hesitation, handed it to Neeson, and asked, "Is it enough?"

"enough."

"OK."

The conversation between the two was brief, but both were satisfied.

In Sweden, you can’t be too proactive in helping others. You have to make sure that the other person is willing to accept the help. Otherwise, people who see others push their carts and rush up to them, even if they are not reprimanded, will arouse complaints.

The researcher next to Neeson wanted to help him a long time ago, but he could only tear the paper to him after Neeson took the initiative to speak, lest Neeson just like to draw on toilet paper.

Many people regard Swedish customs as a legacy of the Vikings' pirate culture, but the Swedes themselves don't care what others think.

They care more about achieving their goals.

For example, the "dynamic quality re-measurement method" that Yang Rui is explaining has made many people feel closer to the goal.

"The dynamic mass reset method obtains an optical signal. This signal is the sum of all the signaling pathways activated by the G protein-coupled receptor. Only in this way, we cannot judge the cell's response to the G protein coupled receptor, Fortunately, I discovered another point." Yang Rui's lecture was not vivid, but the logic was clear and advanced layer by layer, and the researchers present nodded secretly.

This is the favorite mode of lectures for scientific researchers. It is not boring if there are dry goods, it is a bit like writing official documents.

The researchers were very tight on time, and this time they were willing to attend the lecture because of Yang Rui's fame. Naturally, they wanted to hear useful content.

Yang Rui is also very aware of this point. Occasionally, he will not waste everyone's time guessing, but he continued: "According to my observation, the optical signal is actually different according to different cells, because different cells, Different pathways are expressed depending on the stoichiometry of different signaling pathway components..."

Yang Rui made a brief explanation, then stopped, and said with a smile: "The research I did on ion channels in the first place was actually a little bit involved in this aspect, so when I saw the problem of the signal pathway, I immediately had an idea. .”

Neeson and the researchers around him nodded together, not because they appreciated Yang Rui's sensitivity, but because they hoped that Yang Rui would skip this topic quickly and continue talking.

It is true that Yang Rui did not talk about his own research history, but he still talked about ion channels.

Although several years have passed, Yang Rui's research on potassium ion channels is still world-leading.

This is also a characteristic of high-end scientific research. Unless the people behind you use corpses to pave the way for you, otherwise, the rugged mountain road will always hinder most people from climbing.

For researchers in the industry, whether it is ion channels, light channels or g-protein coupled receptors, it is a difficult problem to solve.

Under normal circumstances, they would not be chasing these complex issues. There is a lot of knowledge in the world, and no one can master it all.

However, the topic raised by Yang Rui is too tempting.

If the dynamic mass re-measurement method can play a role, even if it doesn’t need to be fully effective, as long as it can achieve the 60% to 70% utility described by Yang Rui, it will be the entire pharmaceutical industry that will be changed.

According to Yang Rui, more than 50% of new drug research involving g protein-coupled receptors in the future can be used to screen for active substances in this way.

Think about it, when an active substance is found, then various researches are carried out, and then various clinical tests are carried out, at least tens of millions of dollars will be used as a base. cost in dollars.

Although Yang Rui's dynamic mass re-measurement method cannot shorten this stage, it has the advantage that it can have a deeper understanding of an active substance and can screen out some unqualified active substances.

It is still only a part, but if you think about it, every active substance here used to cost tens of millions of dollars to sieve, and the value of this part is too great.

The researchers present, as long as they think of this point, there is no one who is not serious.

In fact, not only original drugs can use this method, but also generic drugs that are ten times or a hundred times the number can also use this method.

Generic drugs are not copied directly, you also have to follow several steps, and then simplify and simplify, the expense of several million is unavoidable.

If the total cost is counted, the method proposed by Yang Rui now can reduce the total cost even more.

A group of people looked at Yang Rui in admiration with the expression of looking at the silly hat.

Everyone thought it was great that Yang Rui could come up with this routine, but it would be silly to just say it like this.

"Chinese researchers are really pure." Neeson suddenly had the desire to confide, so he said it in Swedish.