The Black Technology Era of Xueba

The idea proposed by Xiao Jianguo is actually not new. Someone is doing it in the Shanghai stock market. It's just that Xiao Jianguo and Xiao Jianying have already run an environmental protection company, so it will be easier to do this.

However, Xiao Ming is not optimistic about this idea, the reason is very simple - there is no technical content.

Your company can recruit garbage sorting and recyclers to collect garbage at your door, and other companies can also do garbage sorting and recycling, which is a thing without any technological content.

If there is more capital intervention, then it will burn money to grab the last chicken feathers in the market just like the shared bicycles and takeaway apps.

Xiao Ming said: "If you don't have the core technology, don't invest rashly. People in business are very smart, and what we think of today will be thought of by others tomorrow. Even if we occupy the waste sorting market, it will definitely be a big deal. A small return on investment can be replaced at any time.”

Xiao Ming's words are actually the true meaning of Pangu Technology's development to this day. If you have core technology, you will not be afraid of competition.

Xiao Ming painted a big cake for Xiao Jianguo and said, "Environmental protection companies can still do it, and garbage sorting must be done, but all of this can be handed over to machines instead of people. People are lazy. Study a detailed plan for garbage classification and disposal, and then you can share it with your uncle."

Xiao Jianguo is definitely willing to listen to Xiao Ming's advice. After all, Xiao Ming is much more experienced in the operation of the company than Xiao Jianguo, who has been a public official for decades.

In the afternoon, Xiao Jianguo and Liu Xiong continued to be students and listened to Xiao Ming's lectures.

Zheng Xuanyu and Lin Weiwei were also familiar with each other. After listening to Zheng Xuanyu talking about what happened in the medical laboratory, Lin Weiwei realized that the laboratory was not a monotonous life, but a rediscovery of the world.

After dinner, Xiao Ming sent Zheng Xuanyu downstairs to go home.

It's not New Year's Eve yet, but the night in Jiangcheng already has a New Year's atmosphere.

The bright fireworks in the night sky and the bright lights in the community all herald the arrival of the new year.

Jiangcheng is one of the few cities that allows citizens to set off fireworks on the streets. After the pollution has eased, the city still allows people to enjoy the happiness at the end of the year and the beginning of the spring.

"Just here, hurry up." Zheng Xuanyu walked to the parking lot.

"Remember what my mother just said?" Xiao Ming asked.

Zheng Xuanyu just covered her mouth and snickered, "Let me come to play often."

The fiery red fireworks reflected on Zheng Xuanyu's face, and her deep eyes also showed a gentle flame...

The citizens of Jiangcheng are still immersed in the atmosphere of the festival, but the Pangu Science and Technology Park is busy on the first working day after the festival.

As the supply of Nananfei C14 micronuclear materials becomes more and more abundant, Tianhe new energy vehicles will be mass-produced this year.

The most busy is the life science laboratory. During the Spring Festival, many experimental personnel actively work overtime in the laboratory, and the research on Ebola virus has made a decisive breakthrough.

Gao Siqi, who had been home for a Spring Festival, came to the laboratory early to take command. Zheng Xuanyu has also become Gao Siqi's most effective assistant. She will be fully responsible for the follow-up treatment, which is very important work.

"The Ebola virus is 970 nanometers in length and is a long filament. It is a single-stranded negative-strand RNA virus with 18,959 bases, an envelope, and a fiber on the surface. The pure virus particle is complexed by a helical ribose nucleocapsid. It consists of a negative-strand linear RNA molecule and four virion structural proteins."

Gao Siqi said: "We start with this envelope, which is the envelope. Its glycoprotein recognizes and binds to host surface receptors, then the viral envelope binds to the host cell membrane, and finally the viral capsid and viral genome enter the host to complete the infection. process."

"Whether it's the capsule or the glycoproteins on its surface,

It all belongs to the gene expression of base combination. That is to say, no matter how the virus replaces the glycoprotein that expresses it in the process of future replication and proliferation, it is actually the expression of genes. "

"The antibody of the human body cannot recognize the virus, and the envelope of the virus can quickly recognize the fusion of human cells. This is the biggest contradiction."

Xiao Ming knew that the laboratory already had the perfect solution and said, "So what?"

"Ebola's glycoproteins will change after repeated replication, so I would like to thank Super Xiaochu, who used the most perfect mathematical thinking and biological logic to find the only commonality of these different glycoproteins, and this small to Molecular-level commonality, we also localized it.

Our method is to tell the human immune system the characteristics of glycoproteins on the surface of Ebola's capsule, and increase the number of human NK cells by means of drugs, relying on NK cells to defeat Ebola by themselves. "

"The way to make the immune system remember is similar to that of traditional virus vaccines, except that traditional vaccines only use an inactivated virus shell, and we use the common molecular point of various forms of Ebola as an antigen."

"Xiaochu, open the video screen!"

A microscopic video of the laboratory research results appeared on the video screen.

Gao Siqi said: "In fact, telling the immune system to let it recognize the Ebola virus is the same as injecting a vaccine. This is not difficult. The more difficult thing is to artificially increase the content of NK cells."

NK cells, also known as natural killer cells, are important immune cells in the human body. At present, in the life science community, the source of this kind is not very clear. Generally, it is derived from the bone marrow, and its development and growth also depend on mature bone marrow cells.

In previous studies, NK cells can be induced by culturing thymocytes in vitro in the presence of cytokines such as IL-2 under laboratory conditions, but this induction cost is extremely high and the cell death rate is extremely high.

How to improve the body's NK cells?

The traditional way is to take Ge-132, or use in vitro culture and then transport it into the human body.

However, both of these methods have drawbacks. The premise of taking Ge-132 to increase NK cells is that the body's immune system is not attacked and not controlled by Ebola, then the signal to generate NK cells can be released.

If you are attacked by Ebola, no matter how much Ge-132 you take, the instruction issued by the immune system is to prevent the production of NK cells.

It is also very unreliable to generate NK cells in vitro and transport them in vivo. First, the cost is high and the technology is difficult. Second, under the interference of the virus, a large number of NK cells from the outside world enter the body to cause a complete disorder of the body's immune system, which not only will not destroy the cells infected by Ebola, but will also cause new diseases. Trouble.

Gao Siqi said: "So there is only one way. When the immune system receives Ebola and enters the body in the first step, it sends an instruction to make every cell in the body produce a large number of NK cells to eliminate Ebola and be infected by it at the first time. cells."