The Black Technology Era of Xueba
Chapter 516 This cell is super fierce!
Gao Siqi said: "This time, we have adopted a similar approach to the treatment of cancer. In the treatment of cancer, we use gene-inducing drugs to prevent the gene expression of tumor cells. Now, we also use gene-inducing drugs, but to stimulate Generation and expression of NK cell populations in somatic tissues."
Gao Siqi described it as a group of NK cells, rather than a single NK cell, because NK cells must cooperate with other similar cells to play an immune effect, such as natural cytotoxic receptors such as NKp46, NKp30, and NKp44.
The totipotency of somatic cells is very low, and Pangu Technology used gene regulation and expression technology to overcome this problem two years ago. This time it is also based on this method to stimulate the production of NK cells, so that each somatic cell is compatible In the battlefield of Ebola, even if the Ebola virus has completely invaded the human immune system, humans can stimulate the vitality of the remaining cells through external treatment to fully strangle Ebola.
Gao Siqi said: "If this treatment method can be clinically successful, then we will achieve a major breakthrough in the war against viruses, and we will be able to successfully treat influenza viruses and even HIV in the future!"
"Also, our treatment has advantages over Maple Leaf's vaccine. Maple Leaf's vaccine can only be given beforehand and is ineffective against the Ebola branch virus and multi-generational Ebola. And our treatment is ineffective. After the infection, even if the disease reaches the middle and late stages, it can still be treated perfectly."
Xiao Ming expressed his concerns and said, "What about the side effects?"
Gao Siqi said: "Theoretically, after killing the Ebola-infected cells, the local NK cells will flow to the whole body with the blood of the cells. If it is a person of ordinary constitution, it will not cause any major harm. If it is a person with allergies, it may cause a series of immune diseases. If it is a woman who is pregnant with a baby, you may need to pay attention to the development of the fetus. As for the specific performance, only clinical experiments are carried out. "
"Have you started a clinical trial?"
"I reported to the relevant departments on the first day of the Spring Festival working day, but... Xia Guo does not have Ebola." Gao Siqi is having a headache.
Perhaps it was because her mind had been on the experiment during this period of time, Gao Siqi rubbed her temples and couldn't think of a better way, "It's a good way to do an experiment in Nan'anfei, but an experiment is always an experiment, and there are risks, if it fails In order to cause the death of patients, we can't do it. After all, the epidemic area is under the attention of the WHO and the Western media."
Zheng Xuanyu came up with the idea of medical experiment at this time and said: "This time our main method is to use the NK cell population in the human immune system, and the NK cell population is not only effective against Ebola virus, but also effective against ordinary influenza, Is it possible to experiment with ordinary flu first?"
In the methods of medical experiments, there is an experimental method that is an analogy experiment. Assuming that drug A is effective on both A and B, and the difficulty of A is lower than that of B, then the drug A can be used to conduct the experiment on A, and if it is successful, then the B experiment.
This experimental method is gradual, and it is also a means for many university laboratories to apply for funding.
XXX university laboratory will say to the relevant higher-level departments: "Look, our drugs are all effective for A, and it is fast for B, but there is still a little funding, please ask for support!"
Zheng Xuanyu completely came up with the idea of university laboratory medical experiments,
"If our treatment is effective against influenza, then a report WHO applies for direct entry into clinical trials in South Anfe," she said.
It is Zheng Xuanyu's request to skip the link of animal experiments and enter the clinical treatment link as soon as possible.
Xiao Ming immediately stated, "I agree, let's use influenza virus as a clinical experiment first. Volunteers should be easy to find."
At this time, Wu Qiwen, the little brother who was doing the virus isolation experiment in the laboratory, raised his hand and said, "What other volunteers are you looking for? It's me. I didn't pay attention when I went home during the Spring Festival, and I got the flu, and I was hanged in the hospital at home for three days. The needles haven't gotten any better, and it's just right now, free treatment."
Wearing a thick mask, Wu Qiwen asked for leave because of a cold a few days ago. Today, he is here to continue the leave and handover work because his condition is more serious.
Wu Qiwen complained: "In the small county hospital where our family is located, I saw a cold. First, I was prescribed more than 200 medicines, but it didn't improve after three days, and then I was prescribed drips and infusions for three days, before and after. It cost me more than 1,000 yuan, and no one will suffer! The basic medical care in my hometown is too problematic, and the medical center in our Pangu Science and Technology Park is better. Not to mention free medical care, people will suffer less."
Wu Qiwen has been fighting the virus throughout the Spring Festival, and he has never felt comfortable.
A cold costs more than 1,000 to 2,000, which is normal now.
Gao Siqi arranged it immediately, "Yes, let's analyze the diseased strain and antigen first."
Wu Qiwen's cold virus was analyzed, and it belongs to the common influenza A.
According to the conventional treatment, it must be anti-inflammatory and anti-viral, and then wait for the body's immune system to completely defeat the virus. The whole event takes two weeks or more.
If NK therapy is used, the virus will be eliminated quickly and the body will recover in a short time.
After one day of pathological analysis and dose determination, Wu Qiwen received the injection of the gene inducer.
The gene inducer will automatically find the cells attacked by the virus, and finally settle in the normal cells near the infected cells, activating the tissues here to continuously produce NK cell populations.
On the day of the injection, Wu Qiwen felt joint pain all over his body, and he also had a fever and a sore throat.
After using the NK gene induction preparation, the fever subsided in half an hour, and the pain was no longer in the evening session.
At noon the next day, the experimental team took Wu Qiwen's blood to test for blood and virus infection, and found that various immune indicators in the blood had increased significantly, including a large increase in the number of NK cells, while the number of viruses in the blood was only one-tenth of yesterday's.
On the third day, Wu Qiwen felt relieved, his nose was yellow, and his physical functions were recovering quickly.
On the fourth day, Wu Qiwen's flu virus completely disappeared from his body, and he also completely recovered.
In just four days, the flu virus that had been arrogant in Wu Qiwen's body for more than half a month was defeated, and he himself did not go through the process of ordinary treatment of flu pain after injecting the NK gene inducer.
Gao Siqi and Zheng Xuanyu completely recorded the entire clinical treatment process.
Xiao Ming said immediately after reading it: "The laboratory has done a good job! If it is written into a paper, it can guide the entire virus medicine community."
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