Military Technology

Hearing Yang Fan's words, everyone couldn't help but nodded.

What Yang Fan said is correct. Indeed, this is a very important issue, and it is also a key to measure the value of this project.

Otherwise, even if the research has made progress and they have successfully bred viruses or bacteria specifically targeting Helicobacter pylori in the stomach, they cannot be put into clinical treatment, let alone marketed.

So everyone couldn't help turning their heads to look at Fang Renzheng, waiting for his answer.

Fang Renzheng nodded with a smile and said: "You are right to worry, this is indeed an important problem we have faced in the entire project research process.

In this project, we actually faced many difficulties.

For example, choose the kind of phage, there are many types of phage, from T1, T2, to T3, T4, T5 and so on. We have to find an ideal phage out of it.

Then, in the targeted culture, it changes the target of attack, from the original bacteria to induction of Helicobacter pylori in the stomach.

This is just the first step, and then we need to stabilize the super phage that we have cultivated against Helicobacter pylori in the stomach so that it has stable DNA.

Thereby variation is not easy to produce in many breeding processes, even put an end to variation. Even if it is mutated, its variant will not cause harm to the human body.

In layman's terms, that is, we want to breed a new type of super phage that specifically targets Helicobacter pylori in the stomach.

If the Helicobacter pylori in the stomach is completely eliminated, the Helicobacter pylori in the stomach will also die quickly after losing the target of attacking the parasite, and will be excreted through human metabolism.

And this new type of super phage is safe enough, it will only attack Helicobacter pylori in the stomach, not other bacteria, let alone human cells and tissues.

In the overshoot of reproduction, there will be no mutation, or it is not easy to produce mutation, even if it is mutation, it will not cause harm to the human body. "

After hearing Fang Renzheng's introduction, everyone nodded involuntarily, as they agreed with his statement.

Seeing this situation, Fang Renzheng smiled slightly, and then continued: "At present, we have found a suitable phage, and after cultivating and inducing it, we have successfully changed its attack target, and then attacked Helicobacter pylori in the stomach.

Please take a look, this is our related experiment screen. "

Under Fang Renzheng's guidance, everyone looked at the big screen in front of them. Immediately, relevant experimental images were played on the big screen, some of which were electron microscope images, and some were demonstration videos.

Through the electron microscope screen, it can be seen that in the petri dish, a dropper dripped a drop of light blue liquid into the petri dish, and then the electron microscope magnified. I saw some strange-looking, even a little scary viruses in these blue liquids, or the bacteriophages were very active and rapidly spreading.

These phages spread out in the petri dish and quickly attacked the gastric H. pylori bacteria in the petri dish. I saw these new super bacteriophages bred, after contacting gastric Helicobacter pylori, they quickly grabbed the gastric Helicobacter pylori cells, and then the very sharp needles pierced into the cells.

Then after a while, the H. pylori in the stomach burst, and many new, smaller superphages emerged from it. These phages are wandering around, looking for new H. pylori bacteria in the stomach.

Fang Renzheng showed a smug look at everyone, and then introduced with a smile: "This is the new type of super phage we have cultivated, and what you see is the electron of this new type of super phage attacking Helicobacter pylori in the stomach in a petri dish." Microscope picture.

For the convenience of watching, we fast-forward the video screen, which is not so fast under normal circumstances.

As you can see, with the passage of time, these new super phages have completely attacked and wiped out all the gastric Helicobacter pylori in the entire petri dish.

In addition to gastric Helicobacter pylori, we also placed other bacteria in the petri dish, such as Escherichia coli, Lactobacillus, Bifidobacterium, Bacteroides, Peptostreptococcus, Weirongococcus and so on.

As you can see, most of these other bacteria are alive. In other words, our new super phage did not attack other bacteria while attacking Helicobacter pylori in the stomach.

Even after all gastric Helicobacter pylori were wiped out, these massively multiplied new super phages lost their attack targets and began to die quickly without attacking other bacteria. "

Hearing Fang Renzheng's introduction, everyone nodded involuntarily, and Wu Hao and Yang Fan also smiled.

Well done, it's amazing what you've been able to achieve in such a short period of time. Wu Hao praised.

Thank you for the compliment. Fang Renzheng thanked him with a smile, and then smiled at Wu Hao: "In fact, this experiment is not perfect. During the monitoring process, we also found that there are new types of super phages attacking other bacteria, but the proportion is relatively small.

In addition, we also found that the new super phages mutated during the reproduction process.

Therefore, for us, this is only the first step of the Long March, and it is still far from being put into clinical trials. "

Wu Hao waved his hands with a smile when he heard the words: "No hurry, no hurry, take your time, I believe you will be able to complete it, and this is already a very remarkable achievement in itself.

How about it, have you written the thesis? "

Fang Renzheng smiled and shook his head: "I've been busy with experiments these days, and I don't have the mind to write papers at all."

Wu Hao shook his head with a smile when he heard the words: "This is not okay. I am busy with the experiment, so I can't forget to write a thesis, and the thesis itself is also a kind of work. This is also your academic achievement. It should be recognized by the entire academic community." Know.

Hurry up and write it, and then publish it early, so that the whole world can learn about our great achievements in this field. "

Speaking of this, Wu Hao said in a calm tone: "And you have to understand that this kind of major achievement should be sooner rather than later. If it is leaked, it will be published by others first. It is important to you, to your entire project team, and to the company. loss."

I understand, I must start writing the paper as soon as possible, and strive to publish it as soon as possible. Fang Renzheng nodded and said.

Hearing Fang Renzheng's words, Qin Yongchuan showed a gratified smile: "That's right, I asked you to do it before, but you didn't do it, saying it would affect the research work.

Now that Mr. Wu has told you, you have to pay attention to it.

This is not only about your personal gains and losses, but also about the interests of your entire team and even the entire company.

So you must take it seriously, and you must not be sloppy. "

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